- ►chestpubs.org J Ansell, J Hirsh, E Hylek, A Jacobson, M … - Chest, 2008 - chestjournal.chestpubs.org This article concerning the pharmacokinetics and pharmacodynamics of vitamin K
antagonists (VKAs) is part of the American College of Chest Physicians
Evidence-Based Clinical Practice Guidelines (8th Edition). It describes the ... Cited by 888 - Related articles - BL Direct - All 21 versions
KM Giacomini, CM Brett, RB Altman, NL … - Clinical Pharmacology & Therapeutics, 2007 - nature.com The NIH Pharmacogenetics Research Network (PGRN) is a collaborative group of
investigators with a wide range of research interests, but all attempting to
correlate drug response with genetic variation. Several research groups ... Cited by 85 - Related articles - All 5 versions
JA Wessels, SM van der Kooij, S le Cessie, W … - Arthritis Rheum, 2007 - interscience.wiley.com ISRCTN no. 32675862. Dr. Allaart has received speaking fees (less than $10,000)
from Schering-Plough. Professors Huizinga and Guchelaar hold a patent for the
methotrexate-responsive predictive model. § Members of the ... Cited by 39 - Related articles - BL Direct - All 4 versions
KM Giacomini, RM Krauss, DM Roden, M … - Nature, 2007 - adsabs.harvard.edu AA(Kathleen M. Giacomini is in the Department of Biopharmaceutical Sciences,
University of California, San Francisco), AB(Ronald M. Krauss is at the
Childrens Hospital Oakland Research Institute), AC(Dan M. Roden is at the ... Cited by 34 - Related articles - BL Direct - All 4 versions
- ►critcaremed.com JP Cobb, AF Suffredini, RL Danner - Critical Care Medicine, 2008 - journals.lww.com From the Center for Critical Illness and Health Engineering and the Departments
of Surgery and Genetics (JPC), Washington University in St. Louis, MO; and
Functional Genomics and Proteomics Facility, Critical Care Medicine ... Cited by 25 - Related articles - All 13 versions
- ►nih.gov DW Nebert, G Zhang, ES Vesell - Drug metabolism reviews, 2008 - informahealthcare.com A brief history of human genetics and genomics is provided, comparing recent
progress in those fields with that in pharmacogenetics and pharmacogenomics,
which are subsets of genetics and genomics, respectively. Sequencing of the ... Cited by 23 - Related articles - BL Direct - All 7 versions
N Huang, V Agrawal, KM Giacomini, WL Miller - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences P450 oxidoreductase (POR) is an electron-donating flavoprotein required for the
activity of all microsomal cytochrome P450 enzymes. We sequenced 5,655 bp of the
POR gene in a representative population of 842 healthy unrelated ... Cited by 16 - Related articles - BL Direct - All 8 versions
DC Crawford, MD Ritchie, MJ Rieder - Pharmacogenomics, 2007 - Future Medicine Genotype–phenotype studies in pharmacogenomics promise to identify the genetic
factors that contribute substantially to variation in individual drug response.
While most genetic association studies have failed to deliver this promise, ... Cited by 15 - Related articles - BL Direct - All 4 versions
- ►purdue.edu [PDF] DM Roden, JM Pulley, MA Basford, GR … - Clinical Pharmacology & Therapeutics, 2008 - nature.com Our objective was to develop a DNA biobank linked to phenotypic data derived
from an electronic medical record (EMR) system. An "opt-out" model was
implemented after significant review and revision. The plan included (i) ... Cited by 14 - Related articles - All 6 versions
T Geisler, E Schaeffeler, J Dippon, S Winter … - Pharmacogenomics, 2008 - Future Medicine Figure 1. Genotype distribution of the CYP2C19*2 polymorphism in patients with
high and low residual platelet aggregation receiving a loading dose of 600 mg
clopidogrel. ... An increasing incidence of carriers of at least one ... Cited by 12 - Related articles - All 4 versions
