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Scholar Results 1 - 10 of about 123 citing Desai: Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. (0.16 sec) 

Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib

- oxfordjournals.org
BI Rini, I Tamaskar, P Shaheen, R Salas, J … - JNCI Journal of the National Cancer Institute, 2007 - jnci.oxfordjournals.org
Sunitinib is an inhibitor of the vascular endothelial growth factor and
platelet-derived growth factor receptors, and it has antitumor activity in
metastatic renal cell carcinoma and gastrointestinal stromal tumors. To ...
Cited by 127 - Related articles - BL Direct - All 6 versions

Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib

- nih.gov
TF Chu, MA Rupnick, R Kerkela, SM … - The Lancet, 2007 - Elsevier
Eight of 75 (11%) patients given repeating cycles of sunitinib in the phase I/II
trial had a cardiovascular event, with congestive heart failure recorded in six
of 75 (8%). Ten of 36 (28%) patients treated at the approved sunitinib dose ...
Cited by 127 - Related articles - All 44 versions

The clinical significance of subclinical thyroid dysfunction

- endojournals.org
B Biondi, DS Cooper - Endocrine Reviews, 2008 - Endocrine Soc
Subclinical thyroid disease (SCTD) is defined as serum free T 4 and free T 3
levels within their respective reference ranges in the presence of abnormal
serum TSH levels. SCTD is being diagnosed more frequently in clinical ...
Cited by 64 - Related articles - BL Direct - All 7 versions

Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and …

- urosource.com [PDF] 
N Bhojani, C Jeldres, JJ Patard, P Perrotte, N … - European Urology, 2008 - Elsevier
Side effects range from <1% to 72%. Grade 3/4 side effects are less common and
range from <1% to 13% for sorafenib, <1% to 16% for sunitinib, and 1% to 20% for
temsirolimus. Overall, sunitinib causes the most grade 3/4 side effects and ...
Cited by 60 - Related articles - All 26 versions

Phase II trial of sorafenib in advanced thyroid cancer

- jcojournal.org
V Gupta-Abramson, AB Troxel, A Nellore, K … - Journal of Clinical Oncology, 2008 - jcojournal.org
Purpose Given the molecular pathophysiology of thyroid cancer and the spectrum
of kinases inhibited by sorafenib, including Raf kinase, vascular endothelial
growth factor receptors, platelet-derived growth factor receptor, and RET ...
Cited by 54 - Related articles - All 7 versions

Renal cell carcinoma: new developments in molecular biology and potential for targeted …

- alphamedpress.org
LJ Costa, HA Drabkin - The oncologist, 2007 - AlphaMed Press
Disclosure: HAD served on the advisory board for sorafenib and for Wyeth. No
other potential conflicts of interest were reported by the authors, planners,
reviewers, or staff managers of this article. ... List the most frequent ...
Cited by 46 - Related articles - BL Direct - All 8 versions

Motesanib diphosphate in progressive differentiated thyroid cancer

- geyseco.info [PDF] 
SI Sherman, LJ Wirth, JP Droz, M Hofmann, L … - The New England journal of medicine, 2008 - nejm.highwire.org
From the University of Texas MD Ander- son Cancer Center, Houston (SIS);
Dana−Farber Cancer Institute, Boston (LJW); Centre Léon Bérard, Lyon, France
(J.-PD); Medical School Bern, Bern, Swit- zerland (MH); Odense University ...
Cited by 37 - Related articles - All 9 versions

A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by …

- endojournals.org
D Mannavola, P Coco, G Vannucchi, R … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Context: Sunitinib (sunitinib malate; SU11248; Sutent; Pfizer Inc., New York,
NY) is a multitarget inhibitor of tyrosine kinases for the treatment of some
human cancers. A myxedematous coma in a patient treated with sunitinib for ...
Cited by 32 - Related articles - BL Direct - All 6 versions

Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid …


E Wong, LS Rosen, M Mulay, A VanVugt, M … - Thyroid, 2007 - liebertonline.com
Objective: Sunitinib is a novel tyrosine kinase inhibitor with antitumor and
antiangiogenic effects. An observed higher than expected rate of hypothyroidism
in sunitinib-treated patients prompted assessment of the incidence of ...
Cited by 30 - Related articles - BL Direct - All 4 versions

Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated …

- oxfordjournals.org
I Tamaskar, R Bukowski, P Elson, AG … - Annals of Oncology, 2007 - Eur Soc Med Oncology
Background: Sorafenib is an orally bioavailable vascular endothelial growth
factor receptor (VEGFR) inhibitor with antitumor activity in metastatic renal
cell carcinoma (RCC). Sunitinib, also a VEGFR inhibitor, induces ...
Cited by 26 - Related articles - BL Direct - All 5 versions


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