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Scholar Results 1 - 10 of about 20 citing Goodman: Stopping at nothing? Some dilemmas of data monitoring in clinical trials. (0.11 sec) 

Why most discovered true associations are inflated

- prsjournal.net
J Ioannidis - Epidemiology, 2008 - journals.lww.com
From the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine,
Ioannina, Greece; and Department of Medicine, Tufts University School of Medicine, Boston,
Massachusetts.
Cited by 48 - Related articles - All 7 versions

Highly active antiretroviral therapy and the incidence of non-AIDS-defining cancers …

- ascopubs.org [PDF] 
T Powles, D Robinson, J Stebbing, J … - Journal of Clinical …, 2008 - jco.ascopubs.org
Eray Goekkurt, Salah-Eddin Al-Batran, Jörg T. Hartmann, Ulrike Mogck, Gunter Schuch, Michael
Kramer, Elke Jaeger, Carsten Bokemeyer, Gerhard Ehninger, and Jan Stoehlmacher From the Department
of Internal Medi- cine I, ...
Cited by 13 - Related articles - All 4 versions

Stopping or reporting early for positive results in randomized clinical trials: The …

- ascopubs.org [PDF] 
EL Korn, B Freidlin, M Mooney - Journal of Clinical Oncology, 2009 - jco.ascopubs.org
Edward L. Korn, Boris Freidlin, and Margaret Mooney From the Biometric Research Branch and the
Clinical Investigations Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and
Diag- nosis, National Cancer ...
Cited by 6 - Related articles - All 6 versions

The JUPITER Trial: Results, Controversies, and Implications for Prevention


PM Ridker - Circulation: Cardiovascular Quality and Outcomes, 2009 - Am Heart Assoc
Statin therapy is effective at reducing cardiovascular event rates among those with prior myocardial
infraction, stroke, diabetes, or overt hyperlipidemia, and current guidelines strongly recommend
lipid-lowering therapy among these ...
Cited by 7 - Related articles

Stopping clinical trials early for benefit: Impact on estimation


B Freidlin, EL Korn - Clinical Trials, 2009 - ctj.sagepub.com
Background It has been suggested in the literature that the well-known bias of treatment-effect
estimators due to the possibility of early stopping for positive results is a major concern with
interim monitoring. Purpose To ...
Cited by 4 - Related articles - All 2 versions

Systematic reviews are not biased by results from trials stopped early for benefit


SN Goodman - Journal of Clinical Epidemiology, 2008 - Elsevier
This comment is made based on simulations where 100% of trials used in a meta-analysis use a
stopping rule (the same rule) that would maximally amplify any effect of such trials. What they mean
by “approximate unbiasedness” ...
Cited by 5 - Related articles - All 6 versions

Valuing and evaluating evidence in medicine

- utoronto.ca [PDF] 
K Borgerson - 2008 - tspace.library.utoronto.ca
Page 1. Valuing and Evaluating Evidence in Medicine by Kirstin Borgerson A thesis submitted in conformity
with the requirements for the degree of Doctor of Philosophy Graduate Department of Philosophy University
of Toronto © Copyright by Kirstin Borgerson (2008) Page 2. ii Abstract ...
Cited by 2 - Related articles - View as HTML - All 2 versions

How Should Adverse Events Be Reported in US Clinical Trials?: Ethical …


AE Shamoo, LI Katzel - Clinical Pharmacology & Therapeutics, 2008 - nature.com
Research with human subjects, including clinical trials, forms the cornerstone of the development of
knowledge on the safety and efficacy of potential drugs and devices. During the conduct of clinical
trials, human subjects may ...
Cited by 1 - Related articles - All 4 versions

A study to sustain the hypothesis of the multiple genesis of …

- biolreprod.org [PDF] 
G Cavallini, A Crippa, MC Magli, N Cavallini, … - Biology of …, 2008 - Soc Study Reprod
Page 1. 1 TITLE. A study to sustain the hypothesis of the multiple genesis of
oligoasthenoteratospermia in 1 human idiopathic infertile males. 2 3 Running Title.
Idiopathic oligoasthenoteratospermia: a mosaic? 4 5 Giorgio Cavallini 1 , Andor ...
Cited by 1 - Related articles - All 4 versions

Rosuvastatin in Patients with Elevated C-Reactive Protein


RJ Gibbons, A Fugh-Berman, PS Chan, BK … - New England Journal …, 2009 - content.nejm.org
To the Editor: Ridker et al. (Nov. 20 issue) re- port the results of Justification for the Use of
Stat- ins in Prevention: an Intervention Trial Evaluat- ing Rosuvastatin (JUPITER), 1 which showed
that rosuvastatin significantly ...
Cited by 1 - Related articles - All 3 versions


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