- ►hypertension.org.za [PDF] JFE Mann, RE Schmieder, M McQueen, L Dyal, … - The Lancet, 2008 - Elsevier 784 patients permanently discontinued randomised therapy during the trial
because of hypotensive symptoms (406 on combination therapy, 149 on ramipril,
and 229 on telmisartan). The number of events for the composite primary ... Cited by 141 - Related articles - All 62 versions
- ►bice.ch [PDF] R Kunz, M Wolbers, T Glass, JFE Mann - The Lancet, 2008 - Elsevier In this single-centre trial, the researchers investigated the role of
angiotensin-converting enzyme (ACE) inhibitors versus angiotensin-II receptor
blockers versus combination therapy on time to doubling of serum creatinine ... Cited by 48 - Related articles - All 16 versions
PA Sarafidis, GL Bakris - The Lancet, 2008 - Elsevier Blockade of the renin-angiotensin system is the main aim of therapy to slow
progression of chronic kidney disease. Reduction of blood pressure with drugs
that block the renin-angiotensin system (ie, angiotensin-converting-enzyme ... Cited by 19 - Related articles - All 31 versions
M Azizi - Journal of molecular medicine, 2008 - Springer Abstract Initial attempts to inhibit renin in humans have faced numerous
difficulties. Molecular modeling and X-ray crystallography of the active site of
renin have led to the development of new orally active renin inhibitors ... Cited by 11 - Related articles - BL Direct - All 4 versions
M Arıcı, Y Erdem - American Journal of Kidney Diseases, 2009 - Elsevier The renin-angiotensin system (RAS) has an important role in hypertension and the
continuum of cardiovascular and kidney disease. The inhibition of this system,
either with an angiotensin-converting enzyme (ACE) inhibitor or an ... Cited by 10 - Related articles - All 4 versions
- ►pcommed.com [PDF] FH Messerli - Journal of the American College of Cardiology, 2009 - Am Coll Cardio Found Physicians have embraced the concept of dual renin-angiotensin system (RAS)
blockade hoping that it would translate into better blood pressure control as
well as incremental nephroprotective and cardioprotective effects. With ... Cited by 10 - Related articles - All 16 versions
GL Bakris, JR Sowers - The Journal of Clinical Hypertension, 2008 - ingentaconnect.com This report updates concepts on hypertension management in patients with
diabetes. It focuses on clinical outcomes literature published within the last 3
years and incorporates these observations into modifications of established ... Cited by 8 - Related articles - All 2 versions
- ►annals.org PS Parfrey - Annals of Internal Medicine, 2008 - Am Coll Physicians Drugs that affect the renin–angiotensin–aldosterone system are effective in
several important diseases. Using them safely and effectively is a basic
clinical skill for physicians who treat chronic disease in adults. ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org NM Kaplan - Hypertension, 2008 - Am Heart Assoc Fortunately, Treatment of Hypertension in Patients 80 Years of Age or Older
turned out very well, so well that it was stopped prematurely after an average
of 1.8 years of treatment because of the strong evidence of benefit with an ... Cited by 6 - Related articles - All 5 versions
