- ►ahajournals.org KH Hong, YJ Lee, E Lee, SO Park, C Han, H … - Circulation, 2008 - Am Heart Assoc From the Department of Physiology and Functional Genomics, Shands Cancer Center,
University of Florida College of Medicine, Gainesville (K.-HH, YJL, EL, SOP, CH,
MKR, SPO); Lee Gil Ya Cancer and Diabetes Institute, Gachon University of ... Cited by 12 - Related articles - All 9 versions
HW Farber - Circulation, 2008 - Am Heart Assoc This meta-analysis reviewed 16 randomized clinical trials of the 3 approved
classes of therapies through December 2005. A statistically significant increase
in 6-minute walk (6MW) of 42.8 meters was observed, as well as a ... Cited by 11 - Related articles - All 5 versions
R Hamid, JD Cogan, LK Hedges, E Austin, JA … - Hum Mutat, 2009 - interscience.wiley.com Familial pulmonary arterial hypertension (FPAH) is a progressive, fatal disease
caused by mutations in the bone morphogenetic protein receptor type 2 gene
(BMPR2). FPAH is inherited as an autosomal dominant trait, and shows ... Cited by 4 - Related articles - All 2 versions
J West, J Cogan, M Geraci, L Robinson, J … - BMC Medical Genomics, 2008 - biomedcentral.com While BMPR2 mutation strongly predisposes to pulmonary arterial hypertension
(PAH), only 20% of mutation carriers develop clinical disease. This finding
suggests that modifier genes contribute to FPAH clinical expression. Since ... Cited by 3 - Related articles - Cached - All 7 versions
R Souza, C Jardim - European Respiratory Review, 2009 - Eur Respiratory Soc Past decades have witnessed an increasing interest in the field of pulmonary
arterial hypertension (PAH). The large number of publications related to PAH
reflects this interest. As a result, in contrast to 15 yrs ago, there are ... Cited by 2 - Related articles - All 2 versions
L Long, A Crosby, X Yang, M Southwood, PD … - Circulation, 2009 - Am Heart Assoc Methods and Results— We studied BMP/TGF-β signaling in 2 rat models of PAH
due to chronic hypoxia and monocrotaline. In both models, there was a
significant reduction in lung BMP type IA receptor and BMP type II receptor ... Cited by 1 - Related articles - All 5 versions
GD Lewis - Journal of the American College of Cardiology, 2009 - Elsevier In this issue of the Journal, Lam et al. (10) provide the first population-based
report of the prevalence, severity, and prognostic implications of PH in heart
failure (HF) with preserved left ventricular ejection fraction (HFpEF). The ... Cited by 1 - Related articles - All 28 versions
A Hypertension - pathogenesis - pt.wkhealth.com Background—Pulmonary arterial hypertension (PAH) is a rare but fatal lung
disease of diverse origins. PAH is now further subclassified as idiopathic PAH,
familial PAH, and associated PAH varieties. Heterozygous mutations in BMPR2 ...
S Ulrich, J Szamalek-Hoegel, M Hersberger, M … - Respiration, 2009 - content.karger.com Background: Idiopathic pulmonary arterial hypertension (IPAH) and chronic
thromboembolic pulmonary hypertension (CTEPH) share important pathogenic and
clinical features. BMPR2 mutations are important in the pathogenesis of ... Related articles - All 3 versions
RI Fox, CM Fox, G Hughes, M Khamashta, L … - medscape.com The centerpiece of "Ten Topics" has always been APS, with topics including its
pathogenesis, clinical manifestations, and therapy. Clinical reviews,
therapeutic "pearls (of wisdom)," and challenging cases were presented. ... Related articles
