- ►nih.gov [PDF] ES Siris - Journal of Bone and Mineral Research, 1998 - Am Soc Bone Min Res Paget's disease of bone is a localized disorder of bone remodeling. Increased numbers of larger than
normal osteoclasts initiate the process at affected skeletal sites, and the increase in bone
resorption is followed by an ... Cited by 114 - Related articles - BL Direct - All 13 versions
BJ Kennedy - The American Journal of Medicine, 1970 - Elsevier Mithramycin, an inhibitor of the synthesis of ribonucleic acid (RNA), was administered to
fifty-eight patients with a variety of advanced carcinomas. Striking objective improvement occurred
in embryonal cell cancer of the ... Cited by 74 - Related articles - All 2 versions
JA KANIS, RES GRAY - Clinical Orthopaedics and Related Research, 1987 - journals.lww.com Long-Term Follow-up Observations on Treatment in Paget's Disease of Bone John A. Kanis, MD, FRCP,
MRCPath.,* and Richard ES Gray, MRCP** The development of specific inhibitors of bone re- sorption
has revolutionized the treatment of ... Cited by 51 - Related articles - All 3 versions
BJ Kennedy - CA A Cancer Journal for Clinicians - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets. In
this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the ... Cited by 46 - Related articles - All 2 versions
- ►endojournals.org FR Singer, TL Clemens, RA Eusebio, PJ … - Journal of Clinical …, 1998 - Endocrine Soc Thirteen patients with severe Paget's disease of bone [mean serum alkaline phosphatase (SAP) level
17 times the upper limit of normal] were treated with 30 mg oral risedronate daily for 8 weeks.
Patients were followed for 16 weeks ... Cited by 39 - Related articles - BL Direct - All 5 versions
RD Tiegs - Clinical therapeutics, 1997 - Elsevier Paget's disease of bone is a common disorder of unknown etiology characterized by increased bone
remodeling and abnormal bone architecture. The pathologic process is initiated by an increase in
osteoclast-mediated bone ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] JR Condon, SBM Reith, JR Nassim, FJC … - British Medical …, 1971 - pubmedcentral.nih.gov Summary We report data from three patients with severe Pagetes disease of bone who were treated with
mithramycin. Mithramycin infusion resulted in a fail in plasma cal, phosphate, akaline phosphatase,
and uninary hydroxyoline excretion. ... Cited by 29 - Related articles - All 5 versions
MRA Khairi, CC Johnston Jr, RD Altman, HN Wellman, … - JAMA, 1974 - Am Med Assoc A double-blind crossover study was performed in which 50 symptomatic patients with Paget disease
were treated with sodium etidronate (EHDP) doses of 1, 2.5, 5, 10, or 20 mg/kg or were given
placebo. After six months, the ... Cited by 25 - Related articles - All 2 versions
BC Lentle, AS Russell, PG Heslip, JS Percy - Clinical Radiology, 1976 - Elsevier Bone scans and radiographic skeletal surveys have been done in 41 patients who had Paget's disease.
The scintigraphic findings are consistent with what is known of the pathophysiology of Paget's
disease. Diseased bone demonstrates ... Cited by 20 - Related articles - All 3 versions
