- ►nih.gov [PDF] JA Carlson, BB Rogers, RN Sifers, MJ … - Journal of Clinical …, 1989 - pubmedcentral.nih.gov Circulating a,-antitrypsin is synthesized primarily in the liver and secreted into the bloodstream,
where it serves as the major protease inhibitor. The PiZ variant of a1-antitrypsin is asso- ciated
with decreased levels of the ... Cited by 139 - Related articles - All 6 versions
S Eriksson, T Moestrup, I Hägerstrand - Acta Med Scand, 1975 - interscience.wiley.com Abstract. The occurrence of PAS-positive, diastase-resistant, inclusion bodies in hepatocytes has
been used as a marker of heterozygous (Pi MZ) α 1 -antitrypsin deficiency in order to study the
frequency of lung, liver and ... Cited by 56 - Related articles - All 2 versions
[CITATION] Primary liver carcinoma and liver cirrhosis
PE Palmer, AA Ucci, HJ Wolfe - CA A Cancer Journal for Clinicians - interscience.wiley.com Using light microscopic, ultrastructural, histochemical, and immunocytochemical tissue methods, a
comparative study was done on distinctive alpha-1-antitrypsin containing tumor tissue inclusions in
hepatoma, and alpha-1-antitrypsin ... Cited by 33 - Related articles - All 2 versions
- ►nih.gov [PDF] WK Blenkinsopp, GP Haffenden - British Medical Journal, 1977 - jcp.bmj.com Alpha-1-antitrypsin deficiency is associated with chronic liver disease in both children and adults,
and with emphysema in adults. The deficiency can be identified by estimation of serum antitryptic
activity, although antitrypsin is ... Cited by 32 - Related articles - All 4 versions
S Govindarajan, M Ashcavai, RL Peters - Hepatology (Baltimore, Md.) - ncbi.nlm.nih.gov 1: Hepatology. 1981 Nov-Dec;1(6):628-31. alpha-1-Antitrypsin phenotypes in hepatocellular
carcinoma. Govindarajan S, Ashcavai M, Peters RL. alpha-1-Antitrypsin deficiency due to
homozygous Pi ZZ state is reported to be associated with cirrhosis ... Cited by 27 - Related articles
CR Abramowsky, M Cebelin, A Choudhury, … - CA A Cancer Journal … - interscience.wiley.com Periodic acid-Schiff-positive diastase-resistant globules are described in an undifferentiated
(embryonal) sarcoma of the liver in a 14-year-old boy. These globules were shown to contain
alpha-1-antitrypsin (A-1-AT) ... Cited by 27 - Related articles - All 2 versions
- ►oxfordjournals.org SF Thai, JW Allen, AB DeAngelo, MH George, JC … - Carcinogenesis, 2001 - Oxford Univ Press Dichloroacetic acid (DCA) is a major by-product of water disinfection by chlorination. Several
studies have demonstrated the hepatocarcinogenicity of DCA in mice when administered in drinking
water. The mechanism of DCA ... Cited by 20 - Related articles - BL Direct - All 4 versions
M Fried, J Kalra, CF Ilardi, A Sawitsky - CA A Cancer Journal for … - interscience.wiley.com Hepatocellular carcinoma (HCC) occurred in a 28-year-old woman treated for acute lymphocytic
leukemia (ALL) with methotrexate (MTX) and 6-mercaptopurine (6-MP), off all therapy for 15 years,
who was also heterozygous for ... Cited by 17 - Related articles - All 3 versions
