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Scholar Results 1 - 10 of about 81 citing BORDEN: Interferons: rationale for clinical trials in neoplastic disease. (0.06 sec) 

[PDF] Interferon therapy in cancer: from imaginon to interferon


D Goldstein, J Laszlo - Cancer Res, 1986 - AACR
Isaacs and Lindemann first characterized UN in England in 1957; they coined the term to signify a
protein elaborated by virally infected cells that functions to prevent their infection by a second
virus (1). However, difficulties ...
Cited by 144 - Related articles - All 3 versions

Photocarcinogenesis, skin cancer, and aging*


JH Epstein - Journal of the American Academy of Dermatology, 1983 - Elsevier
Nonmelanoma skin cancers, like most malignancies, increase in incidence with increasing age.
However, in general they are not due to the aging process but are primarily due to solar radiation.
Clinically, squamous cell ...
Cited by 130 - Related articles - All 5 versions

Intrathecal interferon in multiple sclerosis


L Jacobs, J O'Malley, A Freeman, J Murawski … - Archives of …, 1982 - archneur.highwire.org
\s=b\Human fibroblast interferon (IFN-\g=b\) was administered by serial lumbar punc- ture to ten
patients with multiple sclerosis (MS). Their clinical courses were com- pared with those of ten MS
control patients who did not ...
Cited by 114 - Related articles - All 7 versions

A multiple-dose phase I trial of recombinant leukocyte A interferon in cancer …


SA Sherwin, JA Knost, S Fein, PG Abrams, KA Foon, JJ … - Jama, 1982 - Am Med Assoc
Eighty-one patients with a variety of refractory disseminated malignant neoplasms have been treated
in the first multiple fixed-dose phase I trial of recombinant leukocyte A interferon (IFL-rA). Each
patient received IFL-rA by ...
Cited by 116 - Related articles - All 3 versions

The role of recombinant interferon alfa-2a in the therapy of cutaneous T-cell …


PA Bunn Jr, DC Ihde, KA Foon - CA A Cancer Journal for Clinicians - interscience.wiley.com
Maximally tolerated doses of interferon alfa-2a, 50 × 10 6 U/m 2 administered intramuscularly (IM)
3 times weeklywere given to 20 patients with advanced stages of cutaneous T-cell lymphoma (CTCL) to
determine the efficacy and toxicity ...
Cited by 95 - Related articles - All 2 versions

Clinical trial of recombinant leukocyte A interferon as initial therapy for favorable …

- ascopubs.org [PDF] 
MJ O'Connell, JP Colgan, MM Oken, RE Ritts … - Journal of Clinical …, 1986 - jco.ascopubs.org
T HE INTERFERONS are a family of low ... From the Division of Medical Oncology, Division of Hema-
tology, and Microbiology Research Laboratory, Mayo Clinic, Rochester, Minn, The Minneapolis Veterans
Administration Hospital, ...
Cited by 88 - Related articles - All 5 versions

Photochemotherapy alone or combined with interferon alpha-2a in the treatment of …


HH Roenigk, TM Kuzel, AP Skoutelis, E Springer, … - Journal of Investigative …, 1990 - nature.com
Eighty-two patients with either mycosis fungoides (MF) or parapsoriasis en plaques were treated with
psoralens ultraviolet A light (PUVA). Clinical and histologic parameters were followed for a period
from 6 months to 10 years. Complete ...
Cited by 81 - Related articles - All 2 versions

Effect of fibroblast, lymphoid, and myeloid interferons on human tumor colony …

- aacrjournals.org [PDF] 
EC Bradley, FW Ruscetti - Cancer Research, 1981 - AACR
A variety of solid and hematological human tumors and normal human bone marrow specimens were
assayed for col ony formation in a short-term soft-agar culture system. The effect of human
fibroblast, lymphoid, and myeloid ...
Cited by 49 - Related articles - All 3 versions

The toxicity of recombinant human interleukin-2 in rats following intravenous …

- nih.gov [PDF] 
YL Matory, AE Chang, EH Lipford III, R … - Journal of the …, 1987 - pubmedcentral.nih.gov
Interleukin-2 (IL-2) is a lymphokine produced by helper T cells that has a variety of
immunomodulating properties in vitro and in vivo in murine models.1-5 The authors have demonstrated
in the laboratory that recombinant ...
Cited by 39 - Related articles - All 5 versions

Effects of alpha and beta interferons on cultured human keratinocytes


M Yaar, RL Karassik, LE Schnipper, BA … - Journal of Investigative …, 1985 - nature.com
Interferons (IF) are a family of glycoproteins known for their antiviral activity and the ability to
inhibit growth and alter behavior of various normal and transformed cell types, both in vivo and in
vitro. Because cultured human ...
Cited by 37 - Related articles - All 3 versions


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