N Wang, DL Silver, P Costet, AR Tall - Journal of Biological Chemistry, 2000 - ASBMB Mutations of the ABC1 transporter have been identified as the defect in Tangier disease, characterized
by low HDL and cholesterol ester accumulation in macrophages. A full-length mouse ABC1 cDNA
was used to investigate the mechanisms of lipid efflux to apoA-I or HDL in transfected 293 ... Cited by 349 - Related articles - BL Direct - All 5 versions
- ►jlr.org JF Oram, RM Lawn - The Journal of Lipid Research, 2001 - ASBMB It is widely believed that HDL functions to transport cholesterol from peripheral cells to the liver
by reverse cholesterol transport, a pathway that may protect against atherosclerosis by clearing
excess cholesterol from arterial cells. A cellular ATP-binding cassette transporter (ABC) ... Cited by 233 - Related articles - BL Direct - All 4 versions
- ►nih.gov SM Clee, JJP Kastelein, M van Dam, M … - Journal of Clinical …, 2000 - Am Soc Clin Investig We and others have recently identified mutations in the ABCA1 gene as the underlying cause
of Tangier disease (TD) and of a dominantly inherited form of familial hypoalphalipoproteinemia
(FHA) associated with reduced cholesterol efflux. We have now identified 13 ABCA1 ... Cited by 207 - Related articles - BL Direct - All 10 versions
- ►jlr.org AD Attie, JP Kastelein, MR Hayden - The Journal of Lipid Research, 2001 - ASBMB The identification of mutations in ABCA1 in patients with Tangier disease and familial HDL deficiency
demonstrated that inadequate transport of phospholipid and cholesterol to the extracellular space
results in the hypercatabolism of lipid-poor nascent HDL particles. However, the ... Cited by 193 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org [PDF] JT Salonen, R Salonen, K Seppanen, R Rauramaa, J … - Circulation, 1991 - Am Heart Assoc HDL, HDL2, and HDL3 Subfractions, and the ... A Prospective Population Study in Eastern Finnish
Men ... Jukka T. Salonen, MD, PhD, MPH; Riitta Salonen, MD; Kari Seppanen, MPh; Rainer
Rauramaa, MD, PhD; and Jaakko Tuomilehto, MD, PhD ... Background. We investigated ... Cited by 196 - Related articles - All 5 versions
- ►ahajournals.org RR Singaraja, LR Brunham, H Visscher, JJP … - … , and vascular biology, 2003 - Am Heart Assoc •Yancy PG, Bortnick AE, Kellner-Weibel G, de la Llera-Moya M, Phillips MC, Rothblat GH. Importance
of different pathways of cellular cholesterol efflux. 2003;23:712–719. •Oram JF. HDL Apolipoproteins
and ABCA1: partner in the removal of excess cellular cholesterol. 2003;23:720–727. ... Cited by 177 - Related articles - BL Direct - All 7 versions
C Serfaty-Lacrosniere, F Civeira, A Lanzberg, P Isaia, J … - Atherosclerosis, 1994 - Elsevier Decreased levels of plasma high density lipoprotein (HDL) cholesterol have been associated
with premature cardiovascular disease (CVD). Tangier disease is an autosomal co-dominant
disorder in which homozygotes have a marked deficiency of HDL cholesterol and ... Cited by 159 - Related articles - All 4 versions
LA Carlson - Eur J Clin Invest, 1982 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 142 - Related articles - All 5 versions
- ►ahajournals.org [PDF] EJ Schaefer, WH Heaton, MG Wetzel, HB … - … , and Vascular Biology, 1982 - Am Heart Assoc Human lymph chylomicrons contain significant quantities of apo Al and A-ll, which can serve
as precursors for these constituents within plasma HDL. 42 This conversion process appears
to be defective in Tangier homozygotes, 43 resulting in rapid and altered apo Al and A-ll ... Cited by 136 - Related articles - All 3 versions
