- ►pnas.org [PDF] O Iliopoulos, AP Levy, C Jiang, WG Kaelin, … - Proceedings of the National Academy of Sciences, 1996 - National Acad Sciences Proc. Natl. Acad. Sci. USA Vol. 93, pp. 10595-10599, October 1996 Biochemistry ... OTHON ILIOPOULOS*, ANDREW P. LEVYt, CHIAN JIANGt, WILLiAM G. KAELIN, JR.*t,
AND MARK A. GOLDBERGt ... *Dana-Farber Cancer Institute and tHematology- ... Cited by 515 - Related articles - BL Direct - All 10 versions
- ►nih.gov [PDF] ER Maher, AT Moore - CURRENT MOLECULAR MEDICINE-NETHERLANDS …, 2004 - bjo.bmj.com Von Hippel-Lindau (VHL) disease is a dominantly inherited familial cancer
syndrome with variable expression. Themost frequent complications are retinal
angiomatosis, cerebellar and spinal haemangioblastomas, and renal cell ... Cited by 415 - Related articles - BL Direct - All 15 versions
O Iliopoulos, A Kibel, S Gray, WG Kaelin - Nature medicine, 1995 - nature.com A partial cDNA sequence for the gene linked to the von Hippel−Lindau (VHL)
syndrome was reported in 1993. Mutation or loss of both VHL alleles has been
documented in sporadic renal cell carcinomas and in the neoplasms that ... Cited by 405 - Related articles - All 4 versions
- ►bloodjournal.org JL Spivak - Blood, 2002 - Am Soc Hematology Polycythemia vera is a clonal disorder arising in a multipotent hematopoietic
progenitor cell that causes the accumulation of morphologically normal red
cells, white cells, platelets, and their progenitors in the absence of a ... Cited by 223 - Related articles - BL Direct - All 7 versions
K Kondo, WG Kaelin - Experimental cell research, 2001 - Elsevier Germline mutations of the von Hippel–Lindau tumor suppressor gene (VHL) in
humans causes a hereditary cancer syndrome characterized by the development of
retinal and central nervous system hemangioblastomas. Other tumors ... Cited by 152 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] AD D'andrea, LI Zon - Journal of Clinical Investigation, 1990 - pubmedcentral.nih.gov Physiologic role oferythropoietin in erythroid differentiation Erythropoietin
(EPO)' is a 34-kD glycoprotein hormone which is the primary regulator of human
erythropoiesis. A cDNA encoding EPO has been isolated (1), and recombinant ... Cited by 115 - Related articles - All 8 versions
- ►ahajournals.org [PDF] JK Perloff, AJ Marelli, PD Miner - Circulation, 1993 - Am Heart Assoc Joseph K. Perloff, MD; Ariane J. Marelli, MD; and Pamela ... Background. Adults
with cyanotic congenital heart disease and elevated hematocrit levels are often ... UCLA Adult Congenital Heart Disease Center Registry were selected for ... Cited by 87 - Related articles - BL Direct - All 6 versions
WG Kaelin - Biochemical and biophysical research communications, 2005 - Elsevier The heterodimeric transcription factor HIF (hypoxia-inducible factor),
consisting of a labile α-subunit and a stable β-subunit, is a master regulator
of genes involved in acute or chronic adaptation to low oxygen. Studies ... Cited by 71 - Related articles - All 6 versions
- ►asnjournals.org WG Kaelin Jr - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Approximately 100 yr ago, the British surgeon Treacher Collins described two
siblings with retinal blood vessel tumors (1). Shortly thereafter, the German
ophthalmologist Eugen von Hippel also described the familial occurrence of ... Cited by 54 - Related articles - BL Direct - All 9 versions
PA Pioli, WFC Rigby - Journal of Biological Chemistry, 2001 - ASBMB The product of the von Hippel-Lindau (VHL) tumor suppressor gene, pVHL,
functions as a ubiquitin-protein isopeptide ligase in regulating HIF-1 protein
turnover, thus accounting for the increased transcription of ... Cited by 48 - Related articles - BL Direct - All 4 versions
