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Scholar Results 1 - 10 of about 37 citing Morris: Coagulopathy associated with hematin treatment for acute intermittent porphyria. (0.11 sec) 

Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of …


HL Bonkovsky, JF Healey, AN Lourie, GG … - Am J Gastroenterol, 1991 - interscience.wiley.com
The purpose of this study was to assess effects of heme administered
intravenously, complexed to human serum albumin, on activities of the hepatic
hemoproteins, cytochrome(s) P-450, and tryptophan pyrrolase, and on the ...
Cited by 52 - Related articles - All 5 versions

Ferriporphyrins and endothelium: a 2-edged sword---promotion of oxidation and induction of …

- hematologylibrary.org
J Balla, G Balla, V Jeney, G Kakuk, HS Jacob, … - Blood, 2000 - bloodjournal.hematologylibrary.org
Medium 199, fetal calf serum (FCS) and Hank's balanced salt solution (HBSS) were
purchased from Life Technology (Rockville, MD); dispase II was from Gibco (Grand
Island, NY); and hydroxyethyl starch was from Du Pont (Wilmington, DE). 51 ...
Cited by 40 - Related articles - BL Direct - All 5 versions

Porphyrias

- oxfordjournals.org
MFM James, RJ Hift - British Journal of Anaesthesia, 2000 - British Jrnl Anaesthesia
The porphyrins play a critical role in biology, being involved in a wide range
of reactions related to oxygen utilization, transport, storage or formation. The
synthetic pathway involved in the production of the porphyrins is complex ...
Cited by 37 - Related articles - BL Direct - All 4 versions

Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on …


RA Galbraith, A Kappas - Hepatology, 1989 - interscience.wiley.com
Tin-mesoporphyrin shares many of the properties of its parent compound,
tin-protoporphyrin. These include competitive inhibition of heme oxygenase,
amelioration of jaundice and suppression of chemically induced hepatic ...
Cited by 33 - Related articles - All 3 versions

Hematin: unique effects of hemostasis

- hematologylibrary.org [PDF] 
R Glueck, D Green, I Cohen, CH Ts' ao - Blood, 1983 - bloodjournal.hematologylibrary.org
. Hematology; all rights reserved Copyright 2007 by The American Society of DC
20036. by the American Society of Hematology, 1900 M St, NW, Suite 200,
Washington Blood (print ISSN 0006-4971, online ISSN 1528-0020), is ...
Cited by 29 - Related articles - All 3 versions

Controlled trial of haem arginate in acute hepatic porphyria


AL Herrick, MR Moore, KEL Mccoll, A Cook, A … - The Lancet, 1989 - Elsevier
A double-blind study comparing placebo and haem arginate was conducted in 12
patients with acute intermittent porphyria. 2 days after admission in attack
patients were randomised to receive intravenous haem arginate 3 mg/kg per ...
Cited by 29 - Related articles - All 6 versions

Thrombophlebitis and disturbed hemostasis following administration of intravenous hematin …


CS Simionatto, R Cabal, RL Jones, RA … - The American Journal of Medicine, 1988 - Elsevier
Acute porphyria episodes are routinely treated with hematin, but side effects,
including disturbances of hemostasis and peripheral thrombophlebitis, are
associated with the compound's use. Thrombophlebitis is particularly ...
Cited by 28 - Related articles - All 3 versions

Induction of heme oxygenase in intestinal epithelial cells: studies in Caco-2 cell cultures


JW Cable, EE Cable, HL Bonkovsky - Molecular and cellular biochemistry, 1993 - Springer
Enterally administered, heme is a good source of iron in humans and other
animals, but the metabolism of heme by enterocytes has not been fully
characterized. Caco-2 cells in culture provide a useful model for studying ...
Cited by 28 - Related articles - BL Direct - All 5 versions

Repression of hepatic &-aminolevulinate synthase by heme and metalloporphyrins: …


EE Cable, JW Cable, HL Bonkovsky - Hepatology, 1993 - interscience.wiley.com
Heme- and tin-chelated metalloporphyrins are known to decrease the activity of
hepatic -aminolevulinate synthase, the rate-controlling enzyme of heme
synthesis. We performed experiments in primary chick embryo liver cells ...
Cited by 27 - Related articles - BL Direct - All 6 versions

An analysis of 112 acute porphyric attacks in Cape Town, South Africa: Evidence that acute …


RJ Hift, PN Meissner - Medicine, 2005 - journals.lww.com
Skip Navigation Links Home > January 2005 - Volume 84 - Issue 1 > An Analysis of
112 Acute Porphyric Attacks in Cape Town, Sou... ... From Lennox Eales
Porphyria Laboratories, Department of Medicine and South African Medical ...
Cited by 27 - Related articles - All 4 versions


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