RW Schrier, V Arroyo, M Bernardi, M Epstein, JH … - Hepatology, 1988 - interscience.wiley.com In this present article, the Peripheral Arterial Vasodilation Hypothesis is proposed as the initiator
of sodium and water retention in cirrhosis. Peripheral arterial vasodilation is one of the earliest
observations in the cirrhotic patient and experimental animals with cirrhosis. Arterial ... Cited by 843 - Related articles - All 3 versions
PY Martin, P Gines, RW Schrier - New England Journal of Medicine, 1998 - content.nejm.org A decade ago, it was proposed that peripheral arterial vasodilation was an important event in
the pathophysiology of ascites formation in patients with cirrhosis. 1 At the same time, nitric oxide
was demonstrated to be a potent vasodilator with a major role in the regulation of ... Cited by 242 - Related articles - BL Direct - All 5 versions
J Clària, W Jiménez, J Ros, M Asbert, A Castro, V … - Hepatology, 1992 - interscience.wiley.com Nitric oxide is a vasodilator tonically secreted by endothelial cells that is involved in the regulation
of arteriolar tone. This study, which includes two protocols, was performed to investigate whether
nitric oxide plays a role in the pathogenesis of arterial hypotension in cirrhosis with ... Cited by 176 - Related articles - All 4 versions
HM Chung, R Kluge, RW Schrier, RJ … - Archives of Internal …, 1986 - archinte.highwire.org \s=b\In the present study, we found that at least 4.4% of 1,088 prospectively studied patients
developed postoperative hypo- natremia (plasma sodium concentration <130 mEq/L). Most patients
(42%) were normovolemic. Edematous states (21%), hyperglycemia (21%), volume ... Cited by 144 - Related articles - All 5 versions
KA Somberg, JR Lake, SJ Tomlanovich, JM … - Hepatology, 1995 - interscience.wiley.com Cirrhosis is frequently complicated by ascites that may become resistant to diuretic therapy. Transjugular
intrahepatic portosystemic shunts (TIPS) represent a new treatment for this debilitating
condition. The aim of this study was to ascertain the clinical efficacy of TIPS, as well as its ... Cited by 134 - Related articles - BL Direct - All 4 versions
RW Schrier - Ann Intern Med, 1990 - smjr.org In studies in experimental animals and in edematous patients, the nonosmotic release of vasopressin
has been found to be consistently associated with activation of the sympathetic nervous and
renin- angiotensin-aldosterone systems. Moreover, the sympathetic ner- vous system is ... Cited by 140 - Related articles - View as HTML - All 3 versions
V Arroyo, J Colmenero - Journal of Hepatology, 2003 - Elsevier Ascites is the most common complication of cirrhosis [1 and 2]. It develops late during the course
of the disease, when there is severe portal hypertension and hepatic insufficiency. Not
surprisingly, it is associated with a poor survival [3] (50% mortality rate within 3 years, Fig. ... Cited by 111 - Related articles - All 4 versions
- ►aspetjournals.org Y Yamamura, S Nakamura, S Itoh, T Hirano, T … - Journal of Pharmacology …, 1998 - ASPET The pharmacological profile and the acute and chronic aquaretic effects of OPC-41061, a novel
nonpeptide human arginine vasopressin (AVP) V 2 -receptor antagonist, were respectively characterized
in HeLa cells expressing cloned human AVP receptors and in conscious male rats. OPC- ... Cited by 102 - Related articles - BL Direct - All 4 versions
- ►ualberta.ca [PDF] V Arroyo, M Guevara, P Ginès - Gastroenterology, 2002 - Elsevier HRS is a major clinical event during the course of decompensated cirrhosis. Although the most
characteristic feature of the syndrome is a functional renal failure caused by an intense renal
vasoconstriction, it is a more generalized process affecting the heart, brain, and the ... Cited by 98 - Related articles - BL Direct - All 17 versions
RM Pérez-Ayuso, V Arroyo, J Camps, A Rimola, J Gaya … - Kidney Int, 1984 - nature.com Evidence that renal prostaglandins are involved in renal water metabolism in cirrhosis. Plasma
antidiuretic hormone (ADH) and urinary prostaglandin E 2 excretion (UPGE 2 V) were measured
in basal conditions, after water restriction, and after water-loading in 10 normal subjects ... Cited by 99 - Related articles - All 2 versions
