DS Alberts, PY Liu, EV Hannigan, R O'Toole, … - The New England journal of medicine, 1996 - nejm.highwire.org Results Of 654 randomized patients, 546 were eligible for the study. The
estimated median survival was significantly longer in the group receiving
intraperitoneal cisplatin (49 months; 95 percent confidence interval, 42 to ... Cited by 601 - Related articles - BL Direct - All 7 versions
- ►aacrjournals.org [PDF] G Los, PHA Mutsaers, WJF van der Vijgh, GS … - Cancer Research, 1989 - AACR Chemotherapy ip is increasingly being tested as a treatment modality for cancer
limited to the peritoneal cavity. We have developed a rat tumor model in which
penetration and distribution of m-diamminedichloropla- tinum(II) into ... Cited by 157 - Related articles - All 3 versions
- ►pmpawareness.org [PDF] M Markman - Critical Reviews in Oncology and Hematology, 1999 - Elsevier The basic aim of intraperitoneal chemotherapy is to expose cancer present within
the peritoneal cavity to higher concentrations of drug for more prolonged time
periods than possible with systemic drug delivery [2 and 3]. In theory, ... Cited by 150 - Related articles - BL Direct - All 9 versions
- ►adisonline.com [PDF] PE Kintzel - Drug Safety, 2001 - ingentaconnect.com Abstract Nephrotoxicity is an inherent adverse effect of certain anticancer
drugs. Renal dysfunction can be categorised as prerenal uraemia, intrinsic
damage or postrenal uraemia according to the underlying pathophysiological ... Cited by 138 - Related articles - BL Direct - All 8 versions
- ►ascopubs.org [PDF] M Markman, B Reichman, T Hakes, W Jones, … - Journal of Clinical Oncology, 1991 - jco.ascopubs.org OVER THE PAST decade, investigators at a ... From the Breast/Gynecology
Service, Department of Medi- cine, and the Gynecology Service, Department of
Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY. Submitted ... Cited by 133 - Related articles - All 7 versions
PC Dedon, RF Borch - Biochemical pharmacology, 1987 - Elsevier Substitution reactions with biologic nucleophiles appear to govern the antitumor
and toxic properties of platinum complexes. In this paper we have characterized
the reactions of several platinum antitumor agents with sulfur-containing ... Cited by 128 - Related articles - All 3 versions
LP Rybak, R Ravi, SM Somani - Toxicological Sciences, 1995 - Soc Toxicology This investigation was undertaken to explain the possible mech- anism(s) of
protection by diethyldithiocarbamate (DDTC) against cisplatin ototoxicity. Male
Wistar rats (250-275 g) underwent pre- treatment auditory brain stem-evoked ... Cited by 120 - Related articles - BL Direct - All 5 versions
PA Andrews, MP Murphy, SB Howell - Cancer Res, 1985 - AACR We have determined the effect of glutathione (GSH) depletion on the cytotoxicity
of three nitrogen mustards, six platinum complexes, and mitomycin C in a human
ovarian carcinoma cell line. GSH levels in COLO 316 cells were depleted by ... Cited by 110 - Related articles - All 4 versions
- ►ascopubs.org AL Feldman, SK Libutti, JF Pingpank, DL … - Journal of Clinical Oncology, 2003 - jco.ascopubs.org Patients and Methods: Forty-nine patients (28 males, 21 females; median age, 47
years; range, 16 to 76 years) with MM underwent laparotomy, tumor resection,
continuous hyperthermic peritoneal perfusion with cisplatin (median dose ... Cited by 106 - Related articles - BL Direct - All 6 versions
- ►ascopubs.org [PDF] T Sautner, F Hofbauer, D Depisch, R … - Journal of Clinical Oncology, 1994 - jco.ascopubs.org Pur ose: The long-term survival probability of pa- tients who undergo surgery
for stage 3 and 4 gastric cancer is poor, predominantly due to metastatic spread
of the tumor. Depending on the type of tumor histology, the pathway of ... Cited by 106 - Related articles - BL Direct - All 6 versions
