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Scholar Results 1 - 10 of about 209 citing Feinstein: An additional basic science for clinical medicine: II. The limitations of randomized.... (0.10 sec) 

Equipoise and the ethics of clinical research

- uwo.ca [PDF] 
B Freedman - Bioethics: An Anthology, 1999 - books.google.com
Equipoise and the Ethics of Clinical Research Benjamin Freedman Abstract The ethics of clinical
research requires equipoise- a state of genuine uncertainty on the part of the clinical investigator
regarding the comparative therapeutic merits of each arm in a trial. Should the ...
Cited by 879 - Related articles - All 6 versions

Severe functional declines, work, disability, and increased mortality in seventy-five …


T Pincus, LF Callahan, WG Sale, AL Brooks, … - Arthritis Care & … - interscience.wiley.com
Seventy-five patients with rheumatoid arthritis (RA) were reviewed 9 years after an extensive
evaluation which included quantitative measures of functional capacity. These patients had received
multiple intraarticular injections of thiotepa with corticosteroids early in their course, but ...
Cited by 422 - Related articles - All 3 versions

Gastrointestinal Quality of Life Index development, validation and application of a …


E Eypasch, JI Williams, S Wood- … - British Journal of …, 1995 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 398 - Related articles - BL Direct - All 4 versions

Initial antidepressant choice in primary care. Effectiveness and cost of fluoxetine vs …


GE Simon, M VonKorff, JH Heiligenstein, DA Revicki, L … - Jama, 1996 - Am Med Assoc
OBJECTIVE: To compare the clinical, functional, and economic outcomes of initially prescribing
fluoxetine with outcomes of initially selecting imipramine or desipramine. DESIGN: Randomized
controlled trial. SETTING: Primary care clinics of a Seattle, Wash, area staff-model health ...
Cited by 264 - Related articles - BL Direct - All 5 versions

Methodology and overt and hidden bias in reports of 196 double-blind trials of …


PC Gøtzsche - Controlled clinical trials, 1989 - Elsevier
Statistically significant results appeared in 93 reports (47%). In 73 trials they favored only the
new drug, and in 8 only the active control. All 39 trials with a significant difference in side effects
favored the new drug. Choice of dose, multiple comparisons, wrong calculation, subgroup ...
Cited by 220 - Related articles - All 3 versions

Meta-analysis: statistical alchemy for the 21st century


AR Feinstein - Journal of Clinical Epidemiology, 1995 - Elsevier
Pergamon J din Epidemiol Vol. 48, No. 1, pp. 7179, 1995 Copyright 1995 Elsevicr Science Ltd
Printed in Great Britain. All rights reserved 08954356 95 9.50 + 0.00 METAANALYSIS: STATISTICAL
ALCHEMY FOR THE 21st CENTURY ALVAN R. FEINSTEIN* Yale University School of ...
Cited by 196 - Related articles - BL Direct - All 4 versions

The construction of lay expertise: AIDS activism and the forging of credibility in the …


S Epstein - Science, Technology & Human Values, 1995 - sth.sagepub.com
In an unusual instance of lay participation in biomedical research, US AIDS treatment ... It considers
the inwlications of such interventions for the conduct of medical research; ... One of the most
striking aspects of the conduct of AIDS research in the United States is the diversity of the ...
Cited by 197 - Related articles - BL Direct - All 4 versions

The effectiveness of intensive training for residents in interviewing: a randomized, …

- annals.org
RC Smith, JS Lyles, J Mettler, BE … - Annals of Internal …, 1998 - Am Coll Physicians
Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg Add to Facebook
Add to Reddit Add to Technorati Add to Twitter What's this? ... Background: Interviewing and
the physician-patient relationship are crucial elements of medical care, but residencies ...
Cited by 154 - Related articles - BL Direct - All 5 versions

A framework for clinical evaluation of diagnostic technologies.

- nih.gov [PDF] 
GH Guyatt, PX Tugwell, DH Feeny, RB … - CMAJ: Canadian …, 1986 - pubmedcentral.nih.gov
Most new diagnostic technologies have not been adequately assessedto determine whether
their application improves health. Comprehensive evalu- ation of diagnostic technologies includes
establish- ing technologic capability and determining the range of possible uses, ...
Cited by 132 - Related articles - All 11 versions

Clinical judgment revisited: the distraction of quantitative models


AR Feinstein - Annals of internal medicine, 1994 - Am Coll Physicians
More than 25 years ago, in a book called Clinical Judgment, each act of patient care was described
as having an experimental structure.The “experiments” needed substantial scientific
improvement, however, in quality of basic data, taxonomic classification of phenomena, ...
Cited by 133 - Related articles - BL Direct - All 4 versions


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