JA Winkelstein, MC Marino, RB Johnston Jr, J … - Medicine, 2000 - journals.lww.com From The Immune Deficiency Foundation (JAW, MCM, RBJ, JB, JC, JIG, HLM, SMH, HO,
PQ, RHB, CBF, SJC, HD), Baltimore, Maryland; Johns Hopkins University School of
Medicine (JAW), Baltimore, Maryland; Yale University School of Medicine ... Cited by 447 - Related articles - BL Direct - All 2 versions
JD Pollock, DA Williams, MAC Gifford, LL Li, … - Nature genetics, 1995 - nature.com Chronic granulomatous disease (CGD) is a recessive disorder characterized by a
defective phagocyte respiratory burst oxidase, life−threatening pyogenic
infections and inflammatory granulomas. Gene targeting was used to generate ... Cited by 416 - Related articles - All 3 versions
- ►nih.gov AW Segal, 2004 - Annual Reviews ▪ Abstract Neutrophils provide the first line of defense of the innate immune
system by phagocytosing, killing, and digesting bacteria and fungi. Killing was
previously believed to be accomplished by oxygen free radicals and other ... Cited by 304 - Related articles - BL Direct - All 11 versions
- ►rupress.org [PDF] SH Jackson, JI Gallin, SM Holland - Journal of Experimental Medicine, 1995 - jem.rupress.org Summary Chronic granulomatous disease (CGD) is caused by a congenital defect in
phagocyte reduced nicotinamide dinucleotide phosphate (NADPH) oxidase production
of superoxide and related species. It is characterized by recurrent life- ... Cited by 295 - Related articles - BL Direct - All 3 versions
RM Smith, JT Curnutte - Blood, 1991 - Am Soc Hematology . reserved Hematology; all rights Copyright 2007 by The American Society of
Suite 200, Washington DC 20036. semimonthly by the American Society of
Hematology, 1900 M St, NW, Blood (print ISSN 0006-4971, online ISSN ... Cited by 234 - Related articles - All 3 versions
CB Foster, T Lehrnbecher, F Mol, SM … - Journal of Clinical Investigation, 1998 - pubmedcentral.nih.gov Chronic granulomatous disease (CGD) is an inherited dis- order of phagocyte
function in which defective superoxide production results in deficient
microbicidal activity. CGD patients suffer from recurrent, life-threatening ... Cited by 171 - Related articles - BL Direct - All 8 versions
R Mouy, A Fischer, E Vilmer, R Seger, C … - The Journal of pediatrics, 1989 - Elsevier We retrospectively analyzed the frequency and nature of infections occurring in
48 patients with chronic granulomatous disease. The long-term use of
trimethoprim-sulfamethoxazole and ketoconazole as a preventive therapy for ... Cited by 172 - Related articles - All 5 versions
- ►rupress.org DE Morgenstern, MAC Gifford, LL Li, CM … - Journal of Experimental Medicine, 1997 - jem.rupress.org Mice with X-linked chronic granulomatous disease (CGD) generated by targeted
disruption of the gp91 phox subunit of the NADPH-oxidase complex (X-CGD mice)
were examined for their response to respiratory challenge with Aspergillus ... Cited by 165 - Related articles - BL Direct - All 5 versions
- ►nih.gov AR Cross, AW Segal - BBA-Bioenergetics, 2004 - Elsevier The NADPH oxidase is an electron transport chain in “professional”
phagocytic cells that transfers electrons from NADPH in the cytoplasm, across
the wall of the phagocytic vacuole, to form superoxide. The electron ... Cited by 154 - Related articles - All 5 versions
