JB Ewaschuk, LA Dieleman - World Journal of Gastroenterology, 2006 - wjg.wjgnet.com The prokaryotic and eukaryotic cells of the colon exist in a highly complex, but harmonious
relationship. Disturbances in this remarkable symbiosis can result in the development of inflammatory
bowel diseases (IBD). Although the etiology of IBD is not entirely understood, it is known ... Cited by 70 - Related articles - Cached - BL Direct - All 7 versions
SJ Brown, L Mayer - American Journal of Gastroenterology, 2007 - sovegastro.com Ulcerative colitis (UC) and Crohn's disease (CD), collectively referred to as inflammatory bowel
disease (IBD), present with differing histologic and cytokine profiles. While the precise mechanisms
underlying the development of IBD are not known, sufficient data have been collected to ... Cited by 42 - Related articles - View as HTML - BL Direct - All 5 versions
JT Chang, GR Lichtenstein - Nature Clinical Practice Gastroenterology & …, 2006 - nature.com Gary R Lichtenstein earned his MD from the Mount Sinai School of Medicine in New York
City. He then completed his internship and residency in internal medicine at Duke University
Medical Center in Durham, North Carolina. He completed his fellowship in ... Cited by 29 - Related articles - BL Direct - All 3 versions
G Bamias, F Cominelli - Current opinion in gastroenterology, 2007 - journals.lww.com Purpose of review According to the current paradigm, ulcerative colitis and Crohn's disease occur
in genetically predisposed individuals because of dysregulated immune responses against intraluminal
bacterial antigens. Data have recently accumulated supporting alternative hypotheses for ... Cited by 21 - Related articles - BL Direct - All 4 versions
K Mitsuyama, M Sata, S Rose-John - Cytokine and Growth Factor Reviews, 2006 - Elsevier The pathogenesis of inflammatory bowel disease (IBD) is complex, involving a wide range of
molecules including cytokines. Recent investigations support the important role of an
interleukin-6 (IL-6) signaling pathway in the development of IBD. However, the molecular ... Cited by 19 - Related articles - All 7 versions
L Peyrin-Biroulet, P Desreumaux, WJ Sandborn, JF … - The Lancet, 2008 - Elsevier In the past few years, antagonists of tumour necrosis factor have resulted in unforetold therapeutic
benefits in Crohn's disease, but the magnitude and duration of responses are variable. New
agents are therefore needed. Their development has benefited from advances in the ... Cited by 19 - Related articles - All 40 versions
H Black, M Mendoza, S Murin - Chest, 2007 - chestjournal.chestpubs.org Results: Screening studies using respiratory symptoms, high-resolution CT, and pulmonary function
testing support a high prevalence of respiratory abnormalities among patients with IBD. Case
reports and series document a spectrum of respiratory system involvement that spans ... Cited by 16 - Related articles - BL Direct - All 7 versions
- ►physiology.org RS Dise, MR Frey, RH Whitehead, DB … - American Journal of …, 2008 - Am Physiological Soc Regulated intestinal epithelial cell migration plays a key role in wound healing and maintenance
of a healthy gastrointestinal tract. Epidermal growth factor (EGF) stimulates cell migration and
wound closure in intestinal epithelial cells through incompletely understood mechanisms. ... Cited by 14 - Related articles - BL Direct - All 3 versions
MN Ince, DE Elliott - Surgical Clinics of North America, 2007 - Elsevier Molecular and immunologic mechanisms underlying inflammation in inflammatory bowel disease
(IBD) are largely unknown. Recent studies have helped better characterize genetic and environmental
factors associated with colitis. Discoveries of genetic variants have confirmed that IBD is a ... Cited by 11 - Related articles - All 24 versions
- ►jimmunol.org T Tomita, T Kanai, Y Nemoto, T Totsuka, R … - The Journal of …, 2008 - Am Assoc Immnol We previously demonstrated that IL-7 is produced by intestinal goblet cells and is essential for
the persistence of colitis. It is well known, however, that goblet cells are decreased or depleted
in the chronically inflamed mucosa of animal colitis models or human inflammatory bowel ... Cited by 10 - Related articles - All 2 versions
