- ►nih.gov [PDF] DJR Blom, L Schurmans, I De Waard- … - British Journal of Ophthalmology, 1997 - bjo.bmj.com RESULTS Primary and metastatic lesions, as well as the cell line showed high
levels of expression of the monomorphic determinants of HLA class I. Expression
of the polymorphic HLA-A2 and HLA-A3 antigens was decreased on metastases ... Cited by 20 - Related articles - BL Direct - All 7 versions
I de Waard-siebinga, JGA Houbiers, CGJM … - Ocular Immunology and Inflammation, 1996 - informahealthcare.com Abstract HLA molecules play an important role in the presentation of antigens to
the immune system, including tumor-specific antigens. Uveal melanomas vary in
the level of expression of monomorphic HLA molecules. However, since the ... Cited by 11 - Related articles - BL Direct - All 2 versions
HMH Hurks, JAW Metzelaar-Blok, A Mulder, … - International Journal of Cancer, 2000 - interscience.wiley.com Uveal melanoma is the most common primary intra-ocular tumor in adults and has a
high mortality rate due to liver metastases, for which no effective treatment is
available. To investigate whether immunotherapy might be feasible in uveal ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►iovs.org [PDF] DJ Blom, GP Luyten, C Mooy, S Kerkvliet, AH … - Investigative ophthalmology & visual science, 1997 - ARVO Purpose. Because the expression of human leukocyte antigen (HLA) antigens is
important for immunologic recognition of tumor cells, we determined expression
of locus-specific HLA class I antigens in uveal melanoma and tested whether ... Cited by 49 - Related articles - BL Direct - All 4 versions
- ►iovs.org C Ericsson, S Seregard, A Bartolazzi, E … - Investigative ophthalmology & visual science, 2001 - ARVO PURPOSE. Malignant transformation of cells is frequently associated with
abnormalities in human leukocyte antigen (HLA) expression. These abnormalities
may play a role in the clinical course of the disease, because HLA antigens ... Cited by 45 - Related articles - BL Direct - All 3 versions
- ►iovs.org [PDF] D Ma, GP Luyten, TM Luider, JY Niederkorn - Investigative ophthalmology & visual science, 1995 - ARVO Purpose. The purpose of this study was to determine the susceptibility of human
uveal mela- noma cells to in vitro and in vivo natural killer (NK) cell-mediated
cytolysis and to determine if NK cells influence metastasis from the eye. ... Cited by 36 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] D Ma, JY Niederkorn - Immunology, 1995 - pubmedcentral.nih.gov SUMMARY Intraocular melanomas, especially those of the anteriorsegment, reside
within an immunologically privileged milieu. Aqueous humour contains a variety
of immunomodulatory factors that are believed to contribute to ocular ... Cited by 38 - Related articles - BL Direct - All 4 versions
MJ Jager, HM Hurks, J Levitskaya, R … - Human immunology, 2002 - Elsevier A decrease in the expression of HLA antigens is considered a characteristic of
tumor progression and is considered an important tumor-escape mechanism. In
general, HLA Class I expression is even further decreased on metastases. ... Cited by 38 - Related articles - All 5 versions
I Waard-Siebinga, CGJM Hilders, BE Hansen, … - Graefe's Archive for Clinical and Experimental …, 1996 - Springer I. de Waard-Siebinga (~) JL van Delft - MJ Jager Department of Ophthalmology,
University Hospital Leiden, RO. Box 9600, 2300 RC Leiden, The Netherlands Fax
+31-71-248222 CGJM Hilders Department of Pathology, University Hospital ... Cited by 24 - Related articles - BL Direct - All 3 versions
S Dithmar, J Crowder, MJ Jager, N … - Der Ophthalmologe, 2002 - Springer V erschiedene Risikofaktoren für das uveale Melanom wurden beschrieben. Ein
wesentlicher Risikofaktor ist der his- tologische Zelltyp des Melanoms. Spin-
del- und Epitheloidzelltypen kommen vor (Abb. 1), Letzterer geht mit einer ... Cited by 2 - Related articles - All 2 versions
