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Scholar Results 1 - 10 of about 101 related to Pena: Transforming growth factor β isoforms in human optic nerve heads. (0.12 sec) 

Transforming growth factor β isoforms in human optic nerve heads

- nih.gov [PDF]  - Free from Publisher
J Pena, AW Taylor, CS Ricard, I Vidal, MR … - British Journal of Ophthalmology, 1999 - bjo.bmj.com
RESULTS Immunohistochemistry of glaucomatous samples revealed the presence of
intense staining for TGF-β2 primarily in astrocytes, whereas TGF-β1 was
localised to blood vessels. No TGF-β3 immunoreactivity was observed. There ...
Cited by 48 - Related articles - BL Direct - All 8 versions

Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosa

- iovs.org
W Lambert, R Agarwal, W Howe, AF Clark, RJ … - Investigative ophthalmology & visual science, 2001 - ARVO
METHODS. Synthesis of cDNA and the reverse transcription–polymerase chain
reaction (RT-PCR) were conducted using total RNA obtained from
well-characterized cell lines from the human LC and human optic nerve head ...
Cited by 42 - Related articles - BL Direct - All 3 versions

Cell culture of the human lamina cribrosa

- iovs.org [PDF] 
MR Hernandez, F Igoe, AH Neufeld - Investigative ophthalmology & visual science, 1988 - ARVO
The extracellular matrix of the lamina cribrosa may be important in the changes
in the optic nerve head associated with glaucoma. To investigate the cell
biology of this tissue, human lamina cribrosa was explanted in tissue ...
Cited by 51 - Related articles - All 3 versions

Enhanced tenascin expression associated with reactive astrocytes in human optic nerve …


JDO PENA, HJ VARELA, CS RICARD, MR … - Experimental eye research, 1999 - Elsevier
Tenascin is a large extracellular matrix glycoprotein expressed in neural and
non-neural tissues. In the central nervous system, tenascin is synthesized by
astrocytes during development and wound healing, forming barriers and ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Cells of the human optic nerve head express glial cell line-derived neurotrophic factor ( …


RJ Wordinger, W Lambert, R Agarwal, X Liu, … - Mol Vis, 2003 - molvis.org
Methods: Lamina cribrosa (LC) cells and ONH astrocytes were used from normal
donors of various ages. Total RNA was isolated and subjected to reverse
transcriptase-polymerase chain reaction (RT-PCR) to examine mRNA expression ...
Cited by 19 - Related articles - Cached - All 5 versions

Astrocyte responses in human optic nerve head with primary open-angle glaucoma


HJ Varela, MR Hernandez - Journal of glaucoma, 1997 - journals.lww.com
304 HJ VARELA AND MR HERNANDEZ Astrocytes are the major glial cell type in the
optic nerve head, which is composed of three histologic re- gions: prelaminar,
lamina cribrosa, and postlaminar (7). In the prelaminar region, astrocytes ...
Cited by 78 - Related articles - BL Direct - All 4 versions

Transforming Growth Factor-{beta} 2 Modulated Extracellular Matrix Component Expression …

- iovs.org
R Fuchshofer, M Birke, U Welge-Lussen, D … - Investigative ophthalmology & visual science, 2005 - ARVO
METHODS. Astrocytes were isolated from eyes of five human donors, and cultured
monolayers were treated with 1.0 ng/mL TGF-ß2 for 24 and 48 hours. Expression
of Col1 1, Col3 1, Col4 2, FN, TGM2, CTGF, and TSP-1 was examined by ...
Cited by 39 - Related articles - All 3 versions

Expression of neural cell adhesion molecule (NCAM) characterizes a subpopulation of type …


S Kobayashi, I Vidal, JDO Pena, MR … - Glia, 1997 - interscience.wiley.com
The human optic nerve contains a heterogeneous population of astrocytes. In
situ, a specialized subpopulation of astrocytes was distinguished in the adult
optic nerve head by expression of neural cell adhesion molecule (NCAM). To ...
Cited by 46 - Related articles - BL Direct - All 5 versions

The optic nerve head in glaucomatous optic neuropathy


MR Hernandez, J Pena - Archives of ophthalmology, 1997 - Am Med Assoc
Primary open-angle glaucoma, the most common form of glaucoma, is characterized
by irreversible loss of axons from the optic nerve. Previous research in humans
and monkeys with glaucoma suggests that the site of damage to the axons is ...
Cited by 118 - Related articles - BL Direct - All 6 versions

Changes in the extracellular matrix of the human optic nerve head in primary open-angle …


MR Hernandez, WM Andrzejewska, AH … - American journal of ophthalmology, 1990 - cat.inist.fr
Changes in the extracellular matrix of the human optic nerve head in primary
open-angle glaucoma. MR HERNANDEZ, WM ANDRZEJEWSKA, AH ...
Cited by 109 - Related articles - All 2 versions


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