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Scholar Results 1 - 10 of about 101 related to Heinz: Mycophenolate mofetil inhibits human Tenon fibroblast proliferation by guanosine depletion. (0.09 sec) 

Mycophenolate mofetil inhibits human Tenon fibroblast proliferation by guanosine depletion

- nih.gov
C Heinz, K Heise, T Hudde, KP Steuhl - British Journal of Ophthalmology, 2003 - bjo.bmj.com
Backgroundaim: Mycophenolate mofetil could be a useful antiproliferative drug in
glaucoma filtering surgery. In this study the authors set out to investigate
whether growth inhibition of mycophenolate mofetil on human Tenon ...
Cited by 2 - Related articles - BL Direct - All 8 versions

The effects of single doses of β radiation on the wound healing behaviour of human Tenon's …

- nih.gov - Free from Publisher
PH Constable, JG Crowston, NL Occleston, … - British Journal of Ophthalmology, 2004 - bjo.bmj.com
Conclusions: Growth arresting doses of β radiation have unique effects on the
wound healing behaviour of human Tenon's capsule fibroblasts. There was no
significant effect on cellular migration or contraction, but ECM production ...
Cited by 6 - Related articles - BL Direct - All 7 versions

Antiproliferative effect of mycophenolate mofetil on cultured human Tenon fibroblasts


C Heinz, T Hudde, K Heise, KP Steuhl - Graefe's Archive for Clinical and Experimental …, 2002 - Springer
Abstract Background: Wound heal- ing after glaucoma filtering surgery is often
complicated by exaggerated scarring of the subconjunctival Ten- on's layer.
Therefore, antiprolifera- tives are commonly employed. The ...
Cited by 11 - Related articles - BL Direct - All 4 versions

T lymphocyte mediated lysis of mitomycin C treated Tenon's capsule fibroblasts

- nih.gov - Free from Publisher
JG Crowston, LH Chang, JT Daniels, PT Khaw … - British Journal of Ophthalmology, 2004 - bjo.bmj.com
Methods: IL-2 dependent allogeneic T cells were incubated over a monolayer of
mitomycin C treated or control fibroblasts. Fibroblast numbers were evaluated by
direct counts using phase contrast microscopy. To determine whether T cell ...
Cited by 8 - Related articles - BL Direct - All 8 versions

A new delivery system for 5-fluorouracil using prodrug and converting enzyme

- nih.gov
M Akimoto, T Miyahara, J Arai, A Akimoto, H … - British Journal of Ophthalmology, 2002 - bjo.bmj.com
Methods: Fibroblastic cells from rabbit Tenon's capsule were cultured. The cells
were exposed to 5-FU and 5-FC with or without cytosine deaminase induced by
recombinant adenovirus. In the in vitro study, cell proliferation and DNA ...
Cited by 12 - Related articles - BL Direct - All 8 versions

Gene therapy using p21WAF-1/Cip-1 to modulate wound healing after glaucoma …


G Heatley, J Kiland, B Faha, J Seeman, CL … - Gene Therapy, 2004 - nature.com
Glaucoma is a common eye disease associated with elevated intraocular pressure
(IOP). Lowering IOP is the only acceptable therapy for glaucoma and slows
progression of the disease. Filtration surgery, which introduces a guarded ...
Cited by 14 - Related articles - BL Direct - All 3 versions

Long term growth arrest of human Tenon's fibroblasts following single applications of β …

- nih.gov [PDF]  - Free from Publisher
PH Constable, JG Crowston, NL Occleston, … - British Journal of Ophthalmology, 1998 - bjo.bmj.com
AIMS/BACKGROUND Antimetabolites are increasingly used to manipulate the healing
response after filtration surgery, but problems with thin cystic blebs have been
encountered with the liquid agents commonly used such as 5-fluorouracil and ...
Cited by 14 - Related articles - BL Direct - All 8 versions

Adenoviral p53 gene transfer inhibits human Tenon's capsule fibroblast proliferation

- nih.gov - Free from Publisher
KTM Johnson, F Rödicker, K Heise, C Heinz, … - British Journal of Ophthalmology, 2005 - bjo.bmj.com
Background/aim: Although antiproliferative drugs have been used successfully to
prevent scarring after filtration surgery in patients with glaucoma,
complications associated with their use (such as hypotony or ...
Cited by 8 - Related articles - All 8 versions

Adenoviral p53 gene transfer inhibits human Tenon $# x02019; s capsule fibroblast …


KTM Johnson… - The British Journal of Ophthalmology, 2005 - ukpmc.ac.uk
Background/aim: Although antiproliferative drugs have been used successfully to
prevent scarring after filtration surgery in patients with glaucoma,
complications associated with their use (such as hypotony or ...
Related articles

Growth inhibition of cultured human Tenon's fibroblastic cells by targeting the E2F …


M AKIMOTO, M HANGAI, K OKAZAKI, J … - Experimental eye research, 1998 - Elsevier
The transcription factor E2F regulates the expression of several genes concerned
with cell growth. The ability to inhibit transcription by blocking E2F
expression has great potential in the treatment of proliferative disorders. ...
Cited by 22 - Related articles - BL Direct - All 5 versions


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