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Scholar Results 1 - 10 of about 101 related to Tulley: The relation between c-myc expression and interferon sensitivity in uveal melanoma. (0.11 sec) 

The relation between c-myc expression and interferon sensitivity in uveal melanoma

- nih.gov - Free from Publisher
PN Tulley, M Neale, D Jackson, JS Chana, R … - British Journal of Ophthalmology, 2004 - bjo.bmj.com
Background/aim: Interferons (IFN) are currently being used to treat melanoma,
including some patients with uveal melanoma. IFN is thought to inhibit tumour
growth through downregulation of the c-myc oncogene; the overexpression of ...
Cited by 10 - Related articles - BL Direct - All 10 versions

Posttranscriptional regulation of c-myc proto-oncogene expression and growth inhibition by …


D Chatterjee, TM Savarese - Cancer Chemotherapy and Pharmacology, 1992 - Springer
Summary. Recombinant human interferon-~ ser 17 (IFN-~ ser17), a cytokine that
exhibits both antiviral and anti- proliferative activity against a wide variety
of cell types, causes a time- and dose-dependent inhibition of monolayer ...
Cited by 8 - Related articles - All 3 versions

Transfection of fibroblasts with activated c-myc confers resistance to antigrowth effects of …


M Einat, A Kimchi - Oncogene, 1988 - ncbi.nlm.nih.gov
The Go/G1 to S transition in growth factor-stimulated Balb/c 3T3 fibroblasts is
efficiently blocked by interferons (IFNs). In the present communication we
studied whether deregulated expression of exogenously introduced c-myc ...
Cited by 10 - Related articles

Interferon beta increases c-Myc proteolysis in mouse monocyte/macrophage leukemia cells


X Hu, J Bies, L Wolff - Leukemia research, 2005 - Elsevier
Growth inhibitory activity of interferons (IFNs) has been attributed to several
events. These include rapid induction of cyclin-dependent kinase inhibitors,
such as those in the Cip/Kip and Ink4 families and down-regulation of c-myc ...
Cited by 6 - Related articles - All 8 versions

Measurement of c-myc oncoprotein provides an independent prognostic marker for …


R Grover, DA Ross, GD Wilson, R Sanders - British journal of plastic surgery, 1997 - Elsevier
Patients with melanoma who develop nodal metastatic disease represent a group
with heterogeneous clinical outcome. Nodal positivity remains the most accurate
prognostic marker for regional melanoma although it fails to predict ...
Cited by 32 - Related articles - BL Direct - All 8 versions

Effects of interferon alfa and gamma on human uveal melanoma cells in vitro.

- bmj.com [PDF] 
I de Waard-Siebinga, WM Creyghton, J Kool, … - British Medical Journal, 1995 - bjo.bmj.com
Page 1. doi:10.1136/bjo.79.9.847 1995;79;847-855 Br. J. Ophthalmol. I de Waard-Siebinga,
WM Creyghton, J Kool and MJ Jager uveal melanoma cells in vitro. ...
Cited by 17 - Related articles - BL Direct - All 7 versions

Expression of c-myc oncoprotein represents a new prognostic marker in cutaneous …


R DA, W GD - British Journal of Surgery, 1998 - ingentaconnect.com
Background Overexpression of the c-myc oncoprotein has been observed to be of
prognostic significance in several human cancers. This study was undertaken to
establish whether c-myc has any prognostic significance in melanoma. ...
Cited by 36 - Related articles - BL Direct - All 4 versions

The prognostic importance of c-myc oncogene expression in head and neck melanoma


JS Chana, R Grover, GD Wilson, DA Hudson, … - Annals of plastic surgery, 2001 - journals.lww.com
Melanomas of the head and neck have a poorer prognosis than melanomas arising at
other cutaneous sites. To study the biology of this disease, the expression of
the c-myc oncogene was studied in tumors from 97 patients with head and ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Combined immunologic and anti-angiogenic therapy reduces hepatic micrometastases in a …


H Yang, HE Grossniklaus - Current Eye Research, 2006 - informahealthcare.com
Purpose: To evaluate the combined effect of neoadjuvant intracameral interferon
α -2b and adjuvant low-dose angiostatin in reducing the number of hepatic
micrometastases in a murine model of ocular melanoma. Methods: The ...
Cited by 10 - Related articles - BL Direct - All 6 versions

Neoadjuvant interferon alfa-2b treatment in a murine model for metastatic ocular melanoma: …


S Dithmar, D Rusciano, MJ Lynn, DH Lawson, … - Archives of Ophthalmology, 2000 - Am Med Assoc
Methods The B16-LS9 tissue culture melanoma cells were inoculated into the
posterior intraocular compartment of 3 groups of C57BL/6 mice. The inoculated
eyes were enucleated at 9 days and the mice were euthanized at 26 days ...
Cited by 19 - Related articles - BL Direct - All 4 versions


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