- ►nih.gov - Free from Publisher PB Thomas, T Albini, RK Giri, RF See, M … - British Journal of Ophthalmology, 2005 - bjo.bmj.com Methods: 48 B10-RIII mice were immunised with human interphotoreceptor retinoid
binding protein (IRBP) peptide p161–180. They were divided into three groups
of 16 each and treated orally once daily for 14 days; group one received ... Cited by 12 - Related articles - All 9 versions
C Ulivieri, D Fanigliulo, D Benati, FL Pasini, … - European Journal of Immunology, 2008 - interscience.wiley.com Statins block the activity of HMG-CoA reductase, which catalyses the production
of mevalonate, an intermediate in cholesterol biosynthesis, which is also a
precursor of isoprenoids. In addition to lowering circulating cholesterol, ... Cited by 1 - Related articles - All 3 versions
KL Graham, LY Lee, JP Higgins, L Steinman, … - Arthritis Care & Research - interscience.wiley.com Dr. Steinman is a cofounder and consultant at Bayhill Therapeutics and owns
stock and/or stock options in Bayhill Therapeutics. Dr. Utz is a member of the
Scientific Advisory Board of Monogram Biosciences and XDx, and is a ... Cited by 4 - Related articles - All 3 versions
- ►oxfordjournals.org RW Azuma, J Suzuki, M Ogawa, H Futamatsu, … - Cardiovascular research, 2004 - cardiovascres.oxfordjournals.org Results: Fluvastatin reduced the pathophysiological severity of myocarditis.
Fluvastatin inhibited expression of NF B in the nuclei of myocardium in EAM.
Fluvastatin reduced production of Th1-type cytokines, including interferon ... Cited by 30 - Related articles - All 7 versions
- ►diabetesjournals.org B Lozanoska-Ochser, F Barone, C Pitzalis, … - Diabetes, 2006 - Am Diabetes Assoc Statins, the widely used inhibitors of cholesterol biosynthesis, also have
immunomodulatory properties. Statins have recently been shown to have beneficial
prophylactic and therapeutic effects in actively induced, short-term animal ... Cited by 13 - Related articles - BL Direct - All 4 versions
PT Brinkkoetter, U Gottmann, J Schulte, FJ … - Clinical and Experimental Immunology, 2006 - pubmedcentral.nih.gov Although a beneficial effect of hydroxy-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitors, ie statins, on cell-mediated immunity has been suggested
in vivo and in vitro, little is known about the molecular and biochemical ... Cited by 7 - Related articles - BL Direct - All 6 versions
W Coward, SC Chow - Atherosclerosis, 2006 - Elsevier Statins, which are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors,
are the most effective agents for the lowering of cholesterol in clinical
practice. In addition to their lipid-lowering properties, statins also have ... Cited by 9 - Related articles - All 20 versions
W Liu, WM Li, C Gao, NL Sun - Journal of Autoimmunity, 2005 - Elsevier Myocarditis was induced in 23 Lewis rats by injection of porcine cardiac myosin.
High-dose (10 mg/kg/day) or low-dose (1 mg/kg/day) atorvastatin or vehicle was
administered orally for 3 weeks to rats with EAM at the same time of ... Cited by 22 - Related articles - All 3 versions
- ►jimmunol.org ME Gegg, R Harry, D Hankey, H Zambarakji, … - The Journal of Immunology, 2005 - Am Assoc Immnol Intraocular inflammatory diseases are a common cause of severe visual impairment
and blindness. In an acute mouse model of autoimmune retinal disease, we
demonstrate that treatment with the 3-hydroxy-3-methylglutaryl coenzyme A ... Cited by 33 - Related articles - All 5 versions
- ►cardiovascres.org C Smith, B Halvorsen, K Otterdal, T Waehre, … - Cardiovascular Research, 2008 - cardiovascres.org Methods and results: We performed clinical studies in CAD patients as well as
experimental studies in cells with relevance to atherogenesis [ie endothelial
cells, vascular smooth muscle cells (SMC), and peripheral blood mononuclear ... Cited by 10 - Related articles - All 4 versions
