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Scholar Results 1 - 10 of about 101 related to Shanmuganathan: The efficacy of sirolimus in the treatment of patients with refractory uveitis. (0.16 sec) 

The efficacy of sirolimus in the treatment of patients with refractory uveitis


VA Shanmuganathan, EM Casely, D Raj, RJ … - British Journal of Ophthalmology, 2005 - bjo.bmj.com
Methods: Eight patients with severe non-infectious uveitis were recruited to an
open study. Inclusion criteria were limited to patients whose disease was not
controlled with at least two or more separate steroid sparing ...
Cited by 11 - Related articles - All 8 versions

Topical cyclosporine for treatment of ocular surface disease

- duanesolution.com
GN Foulks - International ophthalmology clinics, 2006 - journals.lww.com
Since its introduction to prevent rejection of solid organ transplants in 1983,
there has been widespread use for protection of kidney, heart, liver, and lung
allografts. 1,2 Systemic dosage of 5 to 15 mg/kg (depending upon the ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Uses and safety profile of ciclosporin in ophthalmology


S Kashani, AA Mearza - Expert Opin. Drug Saf., 2008 - informahealthcare.com
Ciclosporin is a calcineurin inhibitor that acts by primarily inhibiting the
action of T cells. Clinical trials in the early 1980s demonstrated that systemic
ciclosporin was a promising steroid-sparing agent and was also effective in ...
Cited by 6 - Related articles - BL Direct - All 5 versions

The evolving role of sirolimus in renal transplantation

- oxfordjournals.org
P Dupont, AN Warrens - Qjm, 2003 - Oxford Univ Press
Sirolimus (rapamycin) is a macrolide antibiotic isolated from the fungus
Streptomyces hygroscopicus 1 first identified in soil samples from Easter
Island. Structurally similar to the calcineurin inhibitor (CNI) tacrolimus ( ...
Cited by 12 - Related articles - BL Direct - All 4 versions

[PDF] Tacrolimus-rapamycin combination therapy for experimental autoimmune uveoretinitis


E Ikeda, N Hikita, K Eto, M Mochizuki - Japanese journal of ophthalmology, 1997 - nichigan.or.jp
Abstract: Tacrolimus and rapamycin both belong to a new family of
immunosuppressants, immunophilin ligands, but the mechanisms by which they
inhibit T cell activation are differ- ent. Therefore, we tested the ...
Cited by 23 - Related articles - BL Direct - All 5 versions

Methotrexate as a first-line corticosteroid-sparing therapy in a cohort of uveitis and scleritis


A Kaplan-Messas, Y Barkana, I Avni, R … - Ocular Immunology and Inflammation, 2003 - informahealthcare.com
Abstract Purpose: To evaluate the clinical experience with methotrexate as a
first-line corticosteroid-sparing drug in patients with resistant ocular
inflammation. Methods: We retrospectively studied 39 consecutive patients ...
Cited by 18 - Related articles - BL Direct - All 4 versions

Long-term efficacy and tolerance of tacrolimus for the treatment of uveitis


AC Hogan, CE McAvoy, AD Dick, RWJ Lee - Ophthalmology, 2007 - Elsevier
Cited by 10 - Related articles - All 21 versions

The effect of in vivo retinal cooling on the electroretinogram of the rabbit


P Lachapelle, J Benoit, P Guité - Vision Research, 1996 - Elsevier
Purpose. Studies reporting the effect of retinal cooling on the
electroretinogram of mammals have, in most cases, made use of an in vitro
approach where the temperature of the retina was lowered by reducing the ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Ophthalmic cyclosporine use in ocular GVHD

- duanesolution.com
GJ Lelli Jr, DC Musch, A Gupta, QA Farjo, TM … - Cornea, 2006 - journals.lww.com
Results: Thirty-two eyes of 16 patients were included with a mean follow-up of
90 days. Dry eye symptoms improved in 10 patients (62.5%), and corneal
fluorescein staining improved in all eyes (P = 0.0039). Global physician ...
Cited by 12 - Related articles - BL Direct - All 4 versions

New developments in the management of juvenile idiopathic arthritis-related uveitis


ME Zannin, F Zulian - Future Rheumatol., 2008 - Future Medicine
Chronic anterior uveitis is the most important extra-articular complication of
juvenile idiopathic arthritis. It is more frequent in the early-onset forms,
with a higher prevalence in the oligoarticular subtype, and bilateral in ...
Related articles - All 8 versions


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