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Scholar Results 1 - 10 of about 101 related to Arden: Spare the rod and spoil the eye. (0.08 sec) 

Spare the rod and spoil the eye


GB Arden, RL Sidman, W Arap, RO … - British Journal of Ophthalmology, 2005 - bjo.bmj.com
This review presents a new unified view of the pathogenesis of three common
causes of acquired retinal degenerative disease—diabetic retinopathy, age
related macular degeneration, and retinopathy of prematurity. In these ...
Cited by 33 - Related articles - All 13 versions

Functional loss in early age-related maculopathy: the ischaemia postreceptoral hypothesis


B Feigl, B Brown, J Lovie-Kitchin, P Swann - Eye, 2006 - nature.com
We review proposed models and psychophysical and electrophysiological tests
performed in many studies for early age-related maculopathy (ARM). We suggest
that ischaemia is the trigger for impaired retinal pigment epithelium ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Postreceptoral adaptation abnormalities in early age-related maculopathy

- qut.edu.au [PDF] 
B Feigl, B Brown, J Lovie-Kitchin, P Swann - Visual Neuroscience, 2007 - Cambridge Univ Press
Abstract Age-related maculopathyARM! has become the major cause of blindness in
the Western World. Currently its pathogenesis and primary site of functional
damage is not fully understood but ischemia is believed to play a major ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Experimental hypoxia in human eyes: Implications for ischaemic disease


B Feigl, I Stewart, B Brown - Clinical Neurophysiology, 2007 - Elsevier
We used two mfERG paradigms, the fast flicker and slow flash stimulation modes,
to measure neuroretinal activity in five healthy participants who breathed room
air and a reduced oxygen mixture (14% oxygen, balance nitrogen). We ...
Cited by 5 - Related articles - All 20 versions

Effect of darkness on inner retinal hypoxia in diabetes


N Drasdo, Z Chiti, DR Owens, RV North - The Lancet, 2002 - Elsevier
It has been postulated that diabetic retinopathy might be initiated by hypoxia
during the hours of darkness. Oscillatory potentials, which reflect inner
retinal function, are reduced in diabetic patients. We tested the effect of ...
Cited by 15 - Related articles - All 9 versions

An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration


… R Pasqualini, RO Schlingemann, M Hagedorn … - Proceedings of the National Academy of Sciences of …, 2001 - National Acad Sciences
Abnormal angiogenesis accompanies many pathological conditions including cancer,
inflammation, and eye diseases. Proliferative retinopathy because of retinal
neovascularization is a leading cause of blindness in developed countries. ...
Cited by 29 - Related articles - BL Direct - All 10 versions

The retinal vasculature and function of the neural retina in a rat model of retinopathy of …

- iovs.org
K Liu, JD Akula, C Falk, RM Hansen, AB … - Investigative ophthalmology & visual science, 2006 - ARVO
METHODS. Retinopathy was induced by exposing newborn rats to alternating 50% and
10% oxygen until age 14 days. To evaluate the function of the neural retina,
electroretinographic (ERG) responses to full-field stimuli were recorded ...
Cited by 24 - Related articles - BL Direct - All 5 versions

Assessment of multifocal electroretinogram abnormalities and their relation to morphologic …

- nih.gov
C Gerth, D Hauser, PB Delahunt, LS Morse, … - Archives of ophthalmology, 2003 - archopht.highwire.org
Methods Thirty-one eyes from 20 patients ages 58 to 84 years with large drusen (
5 drusen 63 µm diameter) were studied. The mfERGs were recorded with a stimulus
of 103 hexagons and a flash intensity of 2.67 candela (cd) · s -1 · m -2 ...
Cited by 23 - Related articles - BL Direct - All 6 versions

Correlating retinal function and amino acid immunocytochemistry following post-mortem …


BV Bui, AJ Vingrys, M Kalloniatis - Experimental eye research, 2003 - Elsevier
We wanted to determine the characteristics associated with electrophysiological
and neurochemical changes secondary to ischemic insult as well as correlate
these electrophysiological and neurochemical changes. A Ganzfeld source was ...
Cited by 13 - Related articles - All 4 versions

Rod photoreceptor function predicts blood vessel abnormality in retinopathy of prematurity

- iovs.org
JD Akula, RM Hansen, ME Martinez-Perez, AB … - Investigative Ophthalmology & Visual Science, 2007 - ARVO
RESULTS. In both ROP models, rod sensitivity was low at P20. Sensitivity
improved by P60 in the 50/10 model, but remained low in the 75 model. Integrated
curvature was high at P20 in both ROP models, decreased nearly to normal by ...
Cited by 16 - Related articles - BL Direct - All 5 versions


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