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Scholar Results 1 - 10 of about 101 related to Chang: Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease. (0.12 sec) 

Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye …

- nih.gov
JH Chang, PJ McCluskey, D Wakefield - British Journal of Ophthalmology, 2006 - bjo.bmj.com
Microbial agents have an important role in the pathogenesis of various
inflammatory eye diseases, such as uveitis and keratitis. Microbial infections
of the eye such as microbial keratitis, ocular onchocerciasis, bacterial ...
Cited by 42 - Related articles - BL Direct - All 9 versions

Expression of toll-like receptor 4 and its associated lipopolysaccharide receptor complex by …

- iovs.org
JH Chang, P McCluskey, D Wakefield - Investigative ophthalmology & visual science, 2004 - ARVO
RESULTS. Normal human uvea, retina, sclera, and conjunctiva constitutively
expressed TLR4, MD-2, and CD14 mRNA. The protein expression of these molecules
was restricted, however, to resident antigen-presenting cells (APCs) in the ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Toll-like receptor 4 and CD14 expression in human ciliary body and TLR-4 in human iris …


BE Brito, DO Zamora, RA Bonnah, Y Pan, SR … - Experimental eye research, 2004 - Elsevier
We investigated the expression of the functional endotoxin receptor proteins
Toll-like receptor-4 and CD14 in human eyes. Toll-like receptor-4 and CD14
proteins were detected by immunohistochemical analysis of sections of whole ...
Cited by 27 - Related articles - All 3 versions

Toll-like receptors and corneal innate immunity


A Kumar, FSX Yu - Current molecular medicine, 2006 - pubmedcentral.nih.gov
The ocular surface is constantly exposed to a wide array of microorganisms. The
ability of the cornea to recognize pathogens as foreign and eliminate them is
critical to retain its transparency, hence preservation of sight. In the ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Changes in Toll-like receptor (TLR)-2 and TLR4 expression and function but not …

- iovs.org
JH Chang, T Hampartzoumian, B Everett, A … - Investigative Ophthalmology & Visual Science, 2007 - ARVO
RESULTS. A significant reduction in the levels of TLR2 expression was observed
on the neutrophils and monocytes of patients with active AAU compared with that
of healthy control subjects (P < 0.05). IL-6 and IFN- production stimulated ...
Cited by 15 - Related articles - BL Direct - All 2 versions

Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: role …

- iovs.org
A Kumar, J Zhang, FSX Yu - Investigative ophthalmology & visual science, 2004 - ARVO
METHODS. HUCL, a telomerase-immortalized HCEC line, and primary cultures of
HCECs were challenged with live or heat-killed S. aureus, its exoproducts, or
cell wall components lipoteichoic acid (LTA) and peptidoglycan (PGN). I B- ...
Cited by 46 - Related articles - BL Direct - All 4 versions

Uveitis secondary to bacterial products


JT Rosenbaum, HL Rosenzweig, JR Smith, TM … - Ophthalmic Res, 2008 - content.karger.com
Bacteria are suspected contributors to several forms of immune-mediated,
noninfectious forms of uveitis including that associated with ankylosing
spondylitis, sarcoidosis, Behçet's disease and inflammatory bowel disease. ...
Cited by 7 - Related articles - BL Direct - All 4 versions

NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis

- iovs.org
HL Rosenzweig, TM Martin, MM Jann, SR … - Investigative ophthalmology & visual science, 2008 - ARVO
RESULTS. MDP induced an acute, ocular inflammatory response, wherein rolling and
adhering leukocytes within the vasculature were significantly increased within 6
hours after MDP treatment. A minor increase in cellular infiltration ...
Cited by 7 - Related articles - BL Direct - All 3 versions

Triggering of TLR3 by polyI: C in human corneal epithelial cells to induce inflammatory …


M Ueta, J Hamuro, H Kiyono, S Kinoshita - Biochemical and Biophysical Research …, 2005 - Elsevier
Epithelial cells of the ocular surface are key in the first-line defense as a
part of the mucosal immune system against pathogens. We investigated whether
polyI:C induces the production by human corneal epithelial cells (HCEC) of ...
Cited by 46 - Related articles - All 6 versions

Regulation of endotoxin-induced keratitis by PECAM-1, MIP-2, and toll-like receptor 4

- iovs.org
S Khatri, JH Lass, FP Heinzel, WM Petroll, … - Investigative ophthalmology & visual science, 2002 - ARVO
1 From the Departments of Medicine and 2 Ophthalmology, Case Western Reserve
University and the Research Institute of University Hospitals of Cleveland,
Cleveland, Ohio; the 3 Department of Ophthalmology, Southwestern Medical ...
Cited by 48 - Related articles - BL Direct - All 4 versions


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