- ►nih.gov K Uno, IA Bhutto, DS McLeod, C Merges, GA … - British Journal of Ophthalmology, 2006 - bjo.bmj.com Results: In the macular region, TSP-1 expression was observed intensely in
Bruch's membrane and weakly in RPE basement membrane, choriocapillaris, and the
wall of large choroidal blood vessels in the aged control eyes. In eyes ... Cited by 11 - Related articles - BL Direct - All 7 versions
- ►nih.gov Q Huang, S Wang, CM Sorenson, N Sheibani - Experimental eye research, 2008 - Elsevier Pigment epithelium derived factor (PEDF) is an endogenous inhibitor of
angiogenesis. However, its physiological role during vascular development and
neovascularization remains elusive. Here we investigated the role of PEDF ... Cited by 3 - Related articles - All 3 versions
IA Bhutto, K Uno, C Merges, L Zhang, DS … - Archives of Ophthalmology, 2008 - Am Med Assoc Methods Immunohistochemical analysis with antibodies against endostatin, pigment
epithelium–derived factor, and thrombospondin 1 was performed on the macular
region of aged control donor eyes (n = 8; mean age, 79.8 years) and eyes ... Cited by 3 - Related articles - BL Direct - All 4 versions
H Uchida, H Hayashi, M Kuroki, K Uno, H … - Experimental eye research, 2005 - Elsevier Vitamin A is essential for the visual system. It is metabolized in the retina
and the resulting product, retinoic acid (RA), greatly affects the structure and
functions of retinal pigment epithelial (RPE) cells. RPE cells produce a ... Cited by 12 - Related articles - All 3 versions
E Scheef, S Wang, CM Sorenson, N Sheibani - Mol Vis, 2005 - molvis.org Methods: Astrocytes were isolated from wild-type and transgenic Immortomice by
collagenase digestion of the retina. Affinity purification using magnetic beads
coated with anti-platelet endothelial cell adhesion molecule-1 (PECAM-1) ... Cited by 7 - Related articles - Cached - All 3 versions
Z Wu, S Wang, CM Sorenson, N Sheibani - Developmental Dynamics, 2006 - interscience.wiley.com Thrombospondin-1 (TSP1) is an endogenous inhibitor of angiogenesis and induces
endothelial cell (EC) apoptosis. To study the role TSP1 plays during vascular
development and neovascularization, we assessed the effects of ectopic TSP1 ... Cited by 9 - Related articles - BL Direct - All 4 versions
IA Bhutto, DS McLeod, T Hasegawa, SY Kim, … - Experimental eye research, 2006 - Elsevier Ocular tissues were obtained from eight aged control donors (age range, 75–86
years; mean age, 79.8 years) with no evidence or history of chorioretinal
disease and from 12 donors diagnosed with AMD (age range, 61–105 years; ... Cited by 42 - Related articles - All 3 versions
S Wang, JL Gottlieb, CM Sorenson, N … - Archives of Ophthalmology, 2009 - Am Med Assoc Results We observed significant amounts of TSP-1 and PEDF in the vitreous
samples of control eyes. The TSP-1 levels varied in samples from patients with
diabetes. In contrast, PEDF levels showed little or no change in vitreous ... Related articles - All 2 versions
Y Wang, 2009 - ohiolink.edu Page 1. GENE DISCOVERY FOR AGE-RELATED MACULAR DEGENERATION by YANG WANG
Submitted in partial fulfillment of the requirements For ... Related articles - View as HTML - All 6 versions
