SA Fisher, A Rivera, LG Fritsche, G … - British Medical Journal, 2007 - bjo.bmj.com Results: The frequency of the Tyr402His C allele was significantly higher in
patients with AMD compared with controls (p M–H = 0.0035). The increased risk
observed in patients homozygous for the C allele (OR HOM = 2.71, 95% CI ... Cited by 16 - Related articles - BL Direct - All 6 versions
- ►nih.gov F Simonelli, G Frisso, F Testa, R di Fiore, DF … - British Journal of Ophthalmology, 2006 - bjo.bmj.com Results: The frequency of c.1277C allele was higher in AMD patients than in
controls (57.2% v 39.3%; p<0.001). The odds ratio (OR; logistic regression
analysis) for AMD was 3.9 (95% confidence interval (CI): 1.9 to 8.2) for CC ... Cited by 32 - Related articles - BL Direct - All 7 versions
S Seitsonen, S Lemmela, J Holopainen, P … - Mol Vis, 2006 - molvis.org Purpose: A strong association of a Tyr402His polymorphism in the complement
factor H (CFH) gene and a Met299Val polymorphism in the elongation of very long
chain fatty acids-like 4 (ELOVL4) gene with age-related macular ... Cited by 29 - Related articles - Cached - All 5 versions
- ►iovs.org RJ Ross, CM Bojanowski, JJ Wang, EY Chew, E … - Investigative ophthalmology & visual science, 2007 - ARVO PURPOSE. Age-related macular degeneration (AMD) is a multifactorial blinding
disease in the elderly. LOC387715 harbors a single-nucleotide polymorphism that
has an association with AMD. This study was conducted to confirm the ... Cited by 30 - Related articles - BL Direct - All 5 versions
S Tanimoto, H Tamura, T Ue, K Yamane, H … - Neuroscience letters, 2007 - Elsevier Age-related macular degeneration (AMD) is one of the leading causes of blindness
among older adults in developed countries and also in Japan. Previous research
suggests that AMD is etiologically a complex disease, caused by multiple ... Cited by 20 - Related articles - All 3 versions
- ►iovs.org PN Baird, FM Islam, AJ Richardson, M Cain, … - Investigative ophthalmology & visual science, 2006 - ARVO RESULTS. Individuals with AMD who had at least one copy of the C allele of Y402H
had an increased risk of disease (odds ratio [OR] 2.98; 95% confidence interval
[CI] 1.81–4.93) compared with cases with the T allele. On subgroup ... Cited by 44 - Related articles - BL Direct - All 4 versions
- ►iovs.org I Kaur, A Hussain, N Hussain, T Das, A … - Investigative ophthalmology & visual science, 2006 - ARVO RESULTS. Significant association was noted with the CFH variant (Tyr402His)
among AMD cases (P = 1.19 x 10 –7 ). Individuals homozygous for the mutant
genotype CC had a significantly higher risk (P < 0.0001) of AMD (OR = ... Cited by 34 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org YP Conley, J Jakobsdottir, T Mah, DE Weeks, R … - Human molecular genetics, 2006 - Oxford Univ Press Age-related maculopathy (ARM) is an important cause of visual impairment in the
elderly population. It is of crucial importance to identify genetic factors and
their interactions with environmental exposures for this disorder. This ... Cited by 64 - Related articles - BL Direct - All 25 versions
PJFSG Dennis, WSBRS Hamond, J Ott, RGWML … - Hum Hered, 2007 - content.karger.com Age-related macular degeneration (AMD) is the lead- ing cause of blindness in
the developed world [1, 2] . It is now undisputed that both genetic [3–5] and
environmen- tal factors [2] contribute to its development. Keys to estab- ... Cited by 28 - Related articles - BL Direct - All 4 versions
J Uka, H Tamura, T Kobayashi, K Yamane, H … - Retina, 2006 - pdfs.journals.lww.com From *Department of Ophthalmology and Visual Science, Grad- uate School of
Biomedical Sciences, and †Department of Epide- miology, Research Institute for
Radiation Biology and Medicine, Hiroshima University, ‡Minamoto Eye ... Cited by 32 - Related articles - BL Direct - All 3 versions
