SV Goverdhan, S Ennis, SR Hannan, KC … - British Journal of …, 2008 - bjo.bmj.com Methods: DNA from 478 cases with AMD and 555 normal controls was genotyped for the
pro-inflammatory IL1β −511C/T, IL6 −174C/G, IL8 −251A/T and anti-inflammatory IL10
−1082G/A cytokine polymorphisms using the 5′ nuclease TaqMan® assay for allelic ... Cited by 7 - Related articles - BL Direct - All 6 versions
- ►iovs.org CL Nordgaard, PP Karunadharma, X Feng, TW Olsen … - … Ophthalmology & Visual …, 2008 - ARVO PURPOSE. Age-related macular degeneration (AMD) is the leading cause of vision loss in individuals
over the age of 65. Histopathological changes become evident in the retinal pigment epithelium
(RPE), a monolayer that provides metabolic support for the overlying photoreceptors, ... Cited by 8 - Related articles - All 3 versions
- ►oxfordjournals.org PJ Francis, B Appukuttan, E Simmons, N … - Human Molecular …, 2008 - Oxford Univ Press Age-related macular degeneration (AMD), a complex multigenic disorder and the most common
cause of vision loss in the elderly, is associated with polymorphisms in the LOC387715/ARMS2
and HTRA1 genes on 10q26. Like humans, macaque monkeys possess a macula and ... Cited by 4 - Related articles - All 4 versions
KH Park, E Ryu, N Tosakulwong, Y Wu, AO … - Molecular …, 2009 - pubmedcentral.nih.gov Seven single nucleotide polymorphisms (SNPs) tagging common haplotypes across SERPING1
were genotyped on 786 (The Mayo Clinic) subjects and the association with AMD studied using
single SNP and haplotype association analyses. The SNP in intron 6 (rs2511989) ... Cited by 5 - Related articles - All 6 versions
[CITATION] Interleukin 8 promoter polymorphism 2251A/T is a risk factor for age related …
- ►nih.gov JD Ding, J Lin, BE Mace, R Herrmann, P Sullivan, C … - Vision research, 2008 - Elsevier Age-related macular degeneration (AMD) is a late-onset, neurodegenerative retinal disease
that shares several clinical and pathological features with Alzheimer's disease (AD) including
extracellular deposits containing amyloid-β (Aβ) peptides. Immunotherapy targeting the ... Cited by 5 - Related articles - All 5 versions
JA Fagerness, JB Maller, BM Neale, RC … - European Journal of …, 2008 - nature.com A case–control association study for advanced age-related macular degeneration was conducted
to explore several regions of interest identified by linkage. This analysis identified a single nucleotide
polymorphism just 3' of complement factor I on chromosome 4 showing significant ... Cited by 13 - Related articles - All 3 versions
- ►iovs.org DDG Despriet, AAB Bergen, JE Merriam, J Zernant, … - … ophthalmology & visual …, 2008 - ARVO 1 From the Department of Clinical and Molecular Ophthalmogenetics, Netherlands Institute for
Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), Amsterdam, The
Netherlands; the 2 Departments of Ophthalmology and 3 Epidemiology and Biostatistics, ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►iovs.org AO Edwards, D Chen, BL Fridley, KM James, Y Wu, G … - … Ophthalmology & Visual …, 2008 - ARVO 1 From the Department of Ophthalmology, the 2 Division of Biostatistics, and the 3 Advanced
Genomics Technology Center, Mayo Clinic, Rochester, Minnesota; the 4 Departments of
Biostatistics, 5 Ophthalmology and Visual Sciences, and 6 Human Genetics, University of ... Cited by 13 - Related articles - BL Direct - All 2 versions
- ►pnas.org JL Haines, KM Spencer, MA Pericak- … - Proceedings of the …, 2007 - National Acad Sciences Age-related macular degeneration (AMD) is an etiologically complex human disease of late
life. Although environmental risk factors have been studied extensively (1), underlying genetic
risk factors stubbornly resisted attempts at discovery until 2005. Since then, several ... Cited by 6 - Related articles - BL Direct - All 6 versions
