R Vigneri, ID Goldfine - Diabetes Care, 1987 - Am Diabetes Assoc Metformin, a biguanide antidiabetic agent that can be administered either alone or in combination
with sulfonylureas, has been extensively used in Europe and Canada. The mechanism of action
of metformin and other biguanides is not completely understood, but recent in vitro and in ... Cited by 28 - Related articles - All 4 versions
CJ Bailey, M Nattrass - Bailliè re's clinical endocrinology and …, 1988 - ncbi.nlm.nih.gov The hyperglycaemia of NIDDM is associated with insulin resistance due, in part, to reduced insulin
receptor binding and more especially postreceptor defects. Metformin is an antihyperglycaemic
agent which can be used to ameliorate insulin resistance. It appears to act directly on ... Cited by 41 - Related articles
A Melander, HE Lebovitz, OK Faber - Diabetes care, 1990 - ncbi.nlm.nih.gov Although controversies remain as to the usefulness of sulfonylureas, most evidence is in favor
of their use in many if not patients with non-insulin-dependent diabetes mellitus. When used
properly, sulfonylureas improve insulin secretion and action, and these effects may be ... Cited by 21 - Related articles - All 2 versions
[CITATION] Effects of metformin on lipoprotein composition in rabbits and man
- ►nih.gov [PDF] JM Lord, SI White, CJ Bailey, TW Atkins, RF Fletcher, … - British Medical Journal, 1983 - bmj.com Page 1. doi:10.1136/bmj.286.6368.830 1983;286;830-831 Br Med J (Clin Res Ed) JM Lord,
SI White, CJ Bailey, TW Atkins, RF Fletcher and KG Taylor and glycaemic control in type II
diabetes. Effect of metformin on insulin receptor binding These include: ... Cited by 26 - Related articles - All 5 versions
A Klip, LA Leiter - Diabetes Care, 1990 - Am Diabetes Assoc Metformin is a hypoglycemic drug effective in the treatment of non-insulin-dependent diabetes
mellitus and increasingly used in Canada and Europe. Effects on intestinal glucose
absorption, insulin secretion, and hepatic glucose production are insufficient to explain its ... Cited by 113 - Related articles - All 4 versions
LS Hermann - Diabète & métabolisme, 1979 - ncbi.nlm.nih.gov In a survey, the pharmacological and clinical documentation of metformin is presented and
discussed, and the present state of knowledge relating to metformin-associated lactic acidosis
is reviewed. The use of metformin in the treatment of diabetes is based on clinical ... Cited by 99 - Related articles
F Féry, L Plat, EO Balasse - Metabolism, 1997 - Elsevier To analyze the effects of metformin (M) on the kinetics and pathways of glucose utilization after
glucose ingestion, nine non-insulin-dependent diabetes mellitus (NIDDM) patients underwent
two 5-hour oral glucose tolerance tests (OGTTs) preceded in random order by a 3-week ... Cited by 26 - Related articles - BL Direct - All 5 versions
