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Scholar Results 1 - 10 of about 101 related to Fajans: Scope and heterogeneous nature of MODY.. (0.12 sec) 

Scope and heterogeneous nature of MODY.


SS Fajans - Diabetes Care, 1990 - Am Diabetes Assoc
This review summarizes aspects of the phenotypic expression, natural history,
recognition, pathogenesis, and heterogeneous nature of maturity-onset diabetes
of the young (MODY), which is inherited in an autosomal-dominant pattern. ...
Cited by 125 - Related articles - All 4 versions

Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in …


G Velho, P Froguel, K Clement, ME Pueyo, B … - Lancet, 1992 - ncbi.nlm.nih.gov
Maturity-onset diabetes of the young (MODY), characterised by
non-insulin-dependent diabetes mellitus (NIDDM) with an early age of onset, is a
genetically heterogeneous disorder. In most MODY kindreds described in ...
Cited by 129 - Related articles - All 4 versions

Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: …


PJ Kaisaki, S Menzel, T Lindner, N Oda, I … - Diabetes, 1997 - Am Diabetes Assoc
We have recently shown that mutations in the gene encoding the transcription
factor hepatocyte nuclear factor (HNF)-1alpha are the cause of one form of
maturity-onset diabetes of the young (MODY3). Here, we report the ...
Cited by 113 - Related articles - BL Direct - All 4 versions

Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY …


WH Herman, SS Fajans, FJ Ortiz, MJ Smith, J … - Diabetes, 1994 - Am Diabetes Assoc
Cited by 73 - Related articles - BL Direct - All 4 versions

Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young …

- pnas.org [PDF] 
GI Bell, KS Xiang, MV Newman, SH Wu, LG … - Proceedings of the National Academy of Sciences, 1991 - National Acad Sciences
Page 1. Proc. Nati. Acad. Sci. USA Vol. 88, pp. 1484-1488, February 1991
Genetics Gene for non-insulin-dependent diabetes mellitus ...
Cited by 190 - Related articles - All 11 versions

Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have …

- pnas.org [PDF] 
M Gidh-Jain, J Takeda, LZ Xu, AJ Lange, N … - Proceedings of the National Academy of Sciences, 1993 - National Acad Sciences
Proc. Natl. Acad. Sci. USA Vol. 90, pp. 1932-1936, March 1993 Biochemustry ...
Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes
mellitus have decreased enzymatic activity: Implications for ...
Cited by 123 - Related articles - BL Direct - All 9 versions

Diabetes complications in NIDDM kindreds linked to the MODY3 locus on chromosome 12q.


G Velho, M Vaxillaire, V Boccio, G … - Diabetes Care, 1996 - Am Diabetes Assoc
OBJECTIVE: To assess the prevalence of diabetes complications and the severity
of diabetes in kindreds with NIDDM linked to the MODY3 locus (chromosome 12q)
and to compare these parameters with data obtained in glucokinase (GCK)- ...
Cited by 58 - Related articles - BL Direct - All 5 versions

Familial hyperglycemia due to mutations in glucokinase--definition of a subtype of diabetes …


P Froguel, H Zouali, N Vionnet, G Velho, M … - New England Journal of Medicine, 1993 - content.nejm.org
Background and Methods Non-insulin-dependent diabetes mellitus (NIDDM) is a
genetically heterogeneous disorder. Maturity-onset diabetes of the young, a form
of NIDDM with an early age of onset and autosomal dominant inheritance, can ...
Cited by 476 - Related articles - BL Direct - All 6 versions

[PDF] A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q


M VaxiHaire, AP Valérie Boccio, C Vigouroux, … - linkage.cpmc.columbia.edu
Page 1. article A gene for maturity onset diabetes of the young (MODY)
maps to chromosome 12q 'CNRS ЕРЮ, Institut Pasteur de Ше ...
Cited by 135 - Related articles - All 4 versions

Maturity-onset diabetes of the young


SS Fajans - Current Opinion in Endocrinology, Diabetes and …, 1995 - journals.lww.com
Maturity-onset diabetes of the young (MODY) is a subtype of
non-insulin-dependent diabetes characterized by an early age of onset and an
autosomal dominant inheritance. Thus far, two forms of MODY have been ...
Cited by 142 - Related articles - BL Direct - All 9 versions


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