A Klip, LA Leiter - Diabetes Care, 1990 - Am Diabetes Assoc Metformin is a hypoglycemic drug effective in the treatment of
non-insulin-dependent diabetes mellitus and increasingly used in Canada and
Europe. Effects on intestinal glucose absorption, insulin secretion, and ... Cited by 113 - Related articles - All 4 versions
O Hother-Nielsen, O Schmitz, PH Andersen, … - Acta Endocrinologica, 1989 - eje.org Abstract. Nine obese patients with Type II diabetes mellitus were examined in a
double-blind cross-over study. Metformin 0.5 g trice daily or placebo were given
for 4 weeks. At the end of each period fasting and day-time postprandial ... Cited by 59 - Related articles - All 5 versions
AB Johnson, JM Webster, CF Sum, L Heseltine … - Metabolism: clinical and experimental, 1993 - ncbi.nlm.nih.gov 1: Metabolism. 1993 Sep;42(9):1217-22. The impact of metformin therapy
on hepatic glucose production and skeletal muscle glycogen ... Cited by 77 - Related articles - BL Direct - All 2 versions
G Perriello, P Misericordia, E Volpi, A … - Diabetes, 1994 - Am Diabetes Assoc To establish the antihyperglycemic mechanisms of metformin in
non-insulin-dependent diabetes mellitus (NIDDM) independently of the long-term,
aspecific effects of removal of glucotoxicity, 21 NIDDM subjects (14 obese, ... Cited by 134 - Related articles - BL Direct - All 4 versions
EI Widen, JG Eriksson, LC Groop - Diabetes, 1992 - Am Diabetes Assoc Many first-degree relatives of patients with non-insulin-dependent diabetes
mellitus (NIDDM) are characterized by insulin resistance. Because metformin
improves peripheral insulin sensitivity, we examined the acute effect of ... Cited by 75 - Related articles - All 4 versions
D Galuska, J Zierath, A Thörne, T … - Diabète & métabolisme, 1991 - ncbi.nlm.nih.gov The effect of metformin (0.1 mM) on glucose transport was investigated in
healthy control and in insulin-resistant human skeletal muscle. Muscle samples
(200-400 mg) were obtained from the rectus abdominis muscle (abdominal ... Cited by 47 - Related articles
E Haupt, B Knick, T Koschinsky, H … - Diabète & métabolisme, 1991 - ncbi.nlm.nih.gov In a multicentre trial in general practice, a total of 1823 type 2 diabetics,
not adequately controlled by diet and maximal sulphonylurea therapy, were
treated with additional metformin 850--2 550 mg/d for 12 weeks. The average ... Cited by 70 - Related articles - All 2 versions
RA DEFRONZO, NIR Barzilai, DC SIMONSON - Journal of Clinical Endocrinology & Metabolism, 1991 - Endocrine Soc The effect of metformin on glucose metabolism was examined in eight obese
(percent ideal body weight, 151 ± 9%) and six lean (percent ideal body weight,
104 ± 4%) noninsulin-dependent diabetic (NIDD) subjects before and after 3 ... Cited by 223 - Related articles - All 3 versions
