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Scholar Results 1 - 10 of about 101 related to Ziegler: Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic.... (0.13 sec) 

Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7 …

- diabetesjournals.org [PDF] 
D Ziegler, M Hanefeld, KJ Ruhnau, H Hasche, … - Diabetes Care, 1999 - Am Diabetes Assoc
CONCLUSIONS — These findings indi- cate that a 3-week intravenous treatment
with -lipoic acid, followed by a 6-month oral tre a t- ment, had no effect on
neuropathic symptoms distinguishable from placebo to a clinically ...
Cited by 193 - Related articles - BL Direct - All 6 versions

Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (α-lipoic acid): A …


M Reljanovic, G Reichel, K Rett, M Lobisch, K … - Free radical research, 1999 - informahealthcare.com
Free Rad. Res., Vol. 31, pp. 171-179 Reprints available directly from the
publisher Photocopying permitted by license only ... © 1999 OPA (Overseas
Publishers Asso~tion) NV Published by license under the Harwood Academic ...
Cited by 125 - Related articles - BL Direct - All 6 versions

Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic …


D Ziegler, H Schatz, F Conrad, FA Gries, H … - Diabetes Care, 1997 - Am Diabetes Assoc
OBJECTIVE: To evaluate the efficacy and safety of oral treatment with the
antioxidant alpha-lipoic acid (ALA) in NIDDM patients with cardiac autonomic
neuropathy (CAN), assessed by heart rate variability (HRV). RESEARCH DESIGN ...
Cited by 107 - Related articles - All 7 versions

Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant α-lipoic acid


D Ziegler, M Hanefeld, KJ Ruhnau, HP Mei\ ner … - Diabetologia, 1995 - Springer
Summary Anti-oxidant treatment has been shown to prevent nerve dysfunction in
experimental diabetes mellitus, thus providing a rationale of potential thera-
peutic value for diabetic patients. The effects of the anti-oxidant ...
Cited by 264 - Related articles - BL Direct - All 4 versions

Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in …


KJ Ruhnau, HP Meissner, JR Finn, M Reljanovic … - Diabetic Medicine, 1999 - ingentaconnect.com
Methods Patients were randomly assigned to oral treatment with 600 mg of TA tid
(n = 12) or placebo (n = 12) for 3 weeks. Neuropathic symptoms (pain, burning,
paraesthesiae, and numbness) in the feet were scored at weekly intervals ...
Cited by 71 - Related articles - BL Direct - All 5 versions

The sensory symptoms of diabetic polyneuropathy are improved with α-lipoic acid

- jiansuo.net [PDF]  - Free from Publisher
AS Ametov, A Barinov, PJ Dyck, R Hermann, N … - Diabetes Care, 2003 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS— Metabolically stable diabetic patients with
symptomatic (stage 2) diabetic sensorimotor polyneuropathy (DSPN) were
randomized to a parallel, double-blind study of ALA (600 mg) (n = 60) or ...
Cited by 171 - Related articles - BL Direct - All 7 versions

Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany: current evidence from …


D Ziegler, M Reljanovic, H Mehnert, FA Gries - Experimental and clinical endocrinology & diabetes: …, 1999 - ncbi.nlm.nih.gov
Diabetic neuropathy represents a major health problem, as it is responsible for
substantial morbidity, increased mortality, and impaired quality of life.
Near-normoglycaemia is now generally accepted as the primary approach to ...
Cited by 144 - Related articles - BL Direct - All 4 versions

alpha-Lipoic acid treatment decreases serum lactate and pyruvate concentrations and …

- diabetesjournals.org [PDF] 
T Konrad, P Vicini, K Kusterer, A Hoflich, A … - Diabetes Care, 1999 - Am Diabetes Assoc
Experimental data have revealed some bene ficial effect of -lipoic acid (LA,
also known as thioctic acid), a potent lipophilic free radical scavenger (1), on
glu- cose metabolism by enhancing glucose uptake in muscle cells (2–4) ...
Cited by 130 - Related articles - BL Direct - All 7 versions

Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve …


M Nagamatsu, KK Nickander, JD Schmelzer, A … - Diabetes Care, 1995 - Am Diabetes Assoc
OBJECTIVE--To determine whether lipoic acid (LA) will reduce oxidative stress in
diabetic peripheral nerves and improve neuropathy. RESEARCH DESIGN AND
METHODS--We used the model of streptozotocin-induced diabetic neuropathy ...
Cited by 241 - Related articles - BL Direct - All 6 versions

Oral administration of RAC-α-lipoic acid modulates insulin sensitivity in patients with type-2 …

- dellonutritionals.com [PDF] 
S Jacob, P Ruus, R Hermann, HJ Tritschler, E … - Free Radical Biology and Medicine, 1999 - Elsevier
In the pathogenesis of type-2 diabetes mellitus, resistance of
insulin-stimulated glucose uptake and impairment of both nonoxidative and
oxidative glucose metabolism play important roles [1 and 2]. ...
Cited by 152 - Related articles - BL Direct - All 10 versions


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