- ►diabetesjournals.org [PDF] D Ziegler, M Hanefeld, KJ Ruhnau, H Hasche, … - Diabetes Care, 1999 - Am Diabetes Assoc CONCLUSIONS — These findings indi- cate that a 3-week intravenous treatment
with -lipoic acid, followed by a 6-month oral tre a t- ment, had no effect on
neuropathic symptoms distinguishable from placebo to a clinically ... Cited by 193 - Related articles - BL Direct - All 6 versions
D Ziegler, H Schatz, F Conrad, FA Gries, H … - Diabetes Care, 1997 - Am Diabetes Assoc OBJECTIVE: To evaluate the efficacy and safety of oral treatment with the
antioxidant alpha-lipoic acid (ALA) in NIDDM patients with cardiac autonomic
neuropathy (CAN), assessed by heart rate variability (HRV). RESEARCH DESIGN ... Cited by 107 - Related articles - All 7 versions
D Ziegler, M Hanefeld, KJ Ruhnau, HP Mei\ ner … - Diabetologia, 1995 - Springer Summary Anti-oxidant treatment has been shown to prevent nerve dysfunction in
experimental diabetes mellitus, thus providing a rationale of potential thera-
peutic value for diabetic patients. The effects of the anti-oxidant ... Cited by 264 - Related articles - BL Direct - All 4 versions
KJ Ruhnau, HP Meissner, JR Finn, M Reljanovic … - Diabetic Medicine, 1999 - ingentaconnect.com Methods Patients were randomly assigned to oral treatment with 600 mg of TA tid
(n = 12) or placebo (n = 12) for 3 weeks. Neuropathic symptoms (pain, burning,
paraesthesiae, and numbness) in the feet were scored at weekly intervals ... Cited by 71 - Related articles - BL Direct - All 5 versions
- ►jiansuo.net [PDF] - Free from Publisher AS Ametov, A Barinov, PJ Dyck, R Hermann, N … - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Metabolically stable diabetic patients with
symptomatic (stage 2) diabetic sensorimotor polyneuropathy (DSPN) were
randomized to a parallel, double-blind study of ALA (600 mg) (n = 60) or ... Cited by 171 - Related articles - BL Direct - All 7 versions
D Ziegler, M Reljanovic, H Mehnert, FA Gries - Experimental and clinical endocrinology & diabetes: …, 1999 - ncbi.nlm.nih.gov Diabetic neuropathy represents a major health problem, as it is responsible for
substantial morbidity, increased mortality, and impaired quality of life.
Near-normoglycaemia is now generally accepted as the primary approach to ... Cited by 144 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] T Konrad, P Vicini, K Kusterer, A Hoflich, A … - Diabetes Care, 1999 - Am Diabetes Assoc Experimental data have revealed some bene ficial effect of -lipoic acid (LA,
also known as thioctic acid), a potent lipophilic free radical scavenger (1), on
glu- cose metabolism by enhancing glucose uptake in muscle cells (2–4) ... Cited by 130 - Related articles - BL Direct - All 7 versions
M Nagamatsu, KK Nickander, JD Schmelzer, A … - Diabetes Care, 1995 - Am Diabetes Assoc OBJECTIVE--To determine whether lipoic acid (LA) will reduce oxidative stress in
diabetic peripheral nerves and improve neuropathy. RESEARCH DESIGN AND
METHODS--We used the model of streptozotocin-induced diabetic neuropathy ... Cited by 241 - Related articles - BL Direct - All 6 versions
- ►dellonutritionals.com [PDF] S Jacob, P Ruus, R Hermann, HJ Tritschler, E … - Free Radical Biology and Medicine, 1999 - Elsevier In the pathogenesis of type-2 diabetes mellitus, resistance of
insulin-stimulated glucose uptake and impairment of both nonoxidative and
oxidative glucose metabolism play important roles [1 and 2]. ... Cited by 152 - Related articles - BL Direct - All 10 versions