M Blüher, J Kratzsch, R Paschke - Diabetes Care, 2001 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Because glucose toxicity per se leads to insulin
resistance, the determination of the primary metabolic alterations leading to
insulin resistance is best accomplished in individuals who are at an ... Cited by 66 - Related articles - BL Direct - All 5 versions
M Fasshauer, J Klein, S Neumann, M … - FEBS letters, 2001 - Elsevier Resistin was recently identified as a hormone secreted by adipocytes which leads
to insulin resistance in vivo and in vitro and might therefore be an important
link between obesity and diabetes. To clarify the regulation of resistin ... Cited by 100 - Related articles - All 5 versions
RD Stith, J Luo - Circulatory shock, 1994 - ncbi.nlm.nih.gov The role of interleukin-6 (IL-6) in carbohydrate metabolism beyond its
inhibition of hepatic phosphoenolpyruvate carboxykinase has not been widely
pursued. To describe such IL-6 effects, we examined in the rat the ... Cited by 48 - Related articles - BL Direct
- ►nih.gov M Fasshauer, J Klein, KM Kriauciunas, K … - Molecular and Cellular Biology, 2001 - Am Soc Microbiol The most widely distributed members of the family of insulin receptor substrate
(IRS) proteins are IRS-1 and IRS-2. These proteins participate in insulin and
insulin-like growth factor 1 signaling, as well as the actions of some ... Cited by 75 - Related articles - BL Direct - All 9 versions
- ►jbc.org M Fasshauer, J Klein, K Ueki, KM … - Journal of Biological Chemistry, 2000 - ASBMB Insulin and insulin-like growth factor I signals are mediated via
phosphorylation of a family of insulin receptor substrate (IRS) proteins, which
may serve both complementary and overlapping functions in the cell. To ... Cited by 87 - Related articles - BL Direct - All 10 versions
A Pfeiffer, J Janott, M Möhlig, M Ristow, H … - Hormone and Metabolic Research, 1997 - thieme-connect.com The cytokine tumor necrosis factor ? (TNF ?) was proposed to mediate obesity
related insulin resistance upon production in fat cells and to participate in
tissue remodelling leading to vascular complications upon being released by ... Cited by 46 - Related articles - BL Direct - All 3 versions
Y Miyazaki, R Pipek, LJ Mandarino, RA … - International Journal of Obesity, 2003 - nature.com The relationship between basal serum tumor necrosis factor alpha (TNF ) levels
and peripheral tissue (muscle) sensitivity to insulin was examined in 63
subjects with normal glucose tolerance (NGT), 18 subjects with impaired ... Cited by 56 - Related articles - BL Direct - All 3 versions
J Klein, M Fasshauer, M Ito, BB Lowell, M … - Journal of Biological Chemistry, 1999 - ASBMB Activity of the sympathetic nervous system is an important factor involved in
the pathogenesis of insulin resistance and associated metabolic and vascular
abnormalities. In this study, we investigate the molecular basis of ... Cited by 84 - Related articles - BL Direct - All 5 versions
M Fickova, S Zorad, L Macho - Hormone and metabolic research= Hormon-und …, 1997 - ncbi.nlm.nih.gov Daily ip administration of thyroxine (T4; 50 micrograms/100 g BW) to adult male
rats for one week doubled the thyroxinemia and induced significant augmentation
of glycemia and insulinemia. Hyperthyroxinemia was also manifested by ... Cited by 12 - Related articles - BL Direct - All 3 versions
GM Reaven, YD Chen - The American journal of medicine, 1988 - ncbi.nlm.nih.gov 1: Am J Med. 1988 Nov 28;85(5A):106-12. Role of abnormal free fatty acid metabolism
in the development of non-insulin-dependent diabetes mellitus. ... Cited by 41 - Related articles - All 2 versions
