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Scholar Results 1 - 10 of about 101 related to Mari: A model-based method for assessing insulin sensitivity from the oral glucose tolerance test. (0.10 sec) 

A model-based method for assessing insulin sensitivity from the oral glucose tolerance test

- diabetesjournals.org
A Mari, G Pacini, E Murphy, B Ludvik, JJ … - Diabetes Care, 2001 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—OGIS requires glucose and insulin concentrations
from a 75-g OGTT at 0, 2, and 3 h (3-h OGTT) or at 0, 1.5, and 2 h (2-h OGTT).
The formula includes six constants optimized to match the clamp results. ...
Cited by 202 - Related articles - BL Direct - All 12 versions

Meal and oral glucose tests for assessment of beta-cell function: modeling analysis in …

- physiology.org
A Mari, O Schmitz, A Gastaldelli, T … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc
We investigated -cell function and its relationship to insulin sensitivity in 17
normal volunteers. For insulin secretion (derived by C-peptide deconvolution), a
mathematical model was applied to 24-h triple-meal tests (MT) as well as ...
Cited by 89 - Related articles - BL Direct - All 5 versions

Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity


M Stumvoll, A Mitrakou, W Pimenta, T Jenssen … - Diabetes Care, 2000 - Am Diabetes Assoc
T he oral glucose tolerance test (OGTT) is a widely used pro cedu re that was
originally developed to classify carbo- hydrate tolerance (1). However, because
plasma glucose and insulin responses dur- ing this test reflect the ability ...
Cited by 380 - Related articles - BL Direct - All 5 versions

Methods for clinical assessment of insulin sensitivity and β-cell function


G Pacini, A Mari - Best Practice & Research Clinical Endocrinology & …, 2003 - Elsevier
The quantitative assessment of insulin sensitivity (IS) and β-cell function
(BCF) is fundamental in the study of metabolic disorders. The most relevant
experimental tests and data analysis methods for assessing both IS and BCF ...
Cited by 84 - Related articles - All 6 versions

Assessing insulin secretion by modeling in multiple-meal tests

- diabetesjournals.org
A Mari, A Tura, A Gastaldelli, E Ferrannini - Diabetes, 2002 - Am Diabetes Assoc
We developed a mathematical model of the glucose control of insulin secretion
capable of quantifying β-cell function from a physiological meal test. The
model includes a static control, ie, a secretion component that is a ...
Cited by 64 - Related articles - BL Direct - All 4 versions

Validation of the insulin sensitivity index (ISI0, 120): comparison with other measures


M Gutt, CL Davis, SB Spitzer, MM Llabre, M … - Diabetes research and clinical practice, 2000 - Elsevier
The purpose of this study was to explore possible calculations using oral
glucose tolerance test (OGTT) values in order to develop a simple measure of
insulin sensitivity. We devised a formula for an insulin sensitivity index, ...
Cited by 138 - Related articles - All 5 versions

Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately …

- eje-online.org [PDF] 
B Ahren, G Pacini - European Journal of Endocrinology, 2004 - EFES
Insulin sensitivity and insulin secretion are mutually related such that insulin
resistance is compen- sated by increased insulin secretion. A correct judgement
of insulin secretion therefore requires vali- dation in relation to the ...
Cited by 109 - Related articles - BL Direct - All 9 versions

Insulin sensitivity indices calculated from basal and OGTT-induced insulin, glucose, and FFA …


F Belfiore, S Iannello, G Volpicelli - Molecular Genetics and Metabolism, 1998 - Elsevier
Insulin Sensitivity Indices for glycemia [ISI(gly)] and blood FFA [ISI(ffa)] can
be calculated with the formulas: ISI(gly) = 2/[(INSp × GLYp) + 1], and ISI(ffa)
= 2/[(INSp × FFAp) + 1], where INSp, GLYp and FFAp = insulinemic, ...
Cited by 111 - Related articles - BL Direct - All 6 versions

Comparative evaluation of simple insulin sensitivity methods based on the oral glucose …


A Mari, G Pacini, AR Brazzale, B Ahren - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: We compared five surrogate insulin sensitivity (IS)
methods against the euglycaemic– hyperinsulinaemic clamp. These methods were
the ho- meostasis model assessment (HOMA) and four methods based on the ...
Cited by 38 - Related articles - All 3 versions

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the …

- diabetesjournals.org [PDF] 
M Matsuda, RA DeFronzo - Diabetes Care, 1999 - Am Diabetes Assoc
F rom the Diabetes Division, Department of Medicine, University of Texas Health
Science Center at San Anto- nio, San Antonio, Te xas . A dd ress correspondence
and reprint requests to Ralph A. DeFronzo, MD, Diabetes Division, Depart ...
Cited by 1123 - Related articles - BL Direct - All 5 versions


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