- Free from Publisher PJ Beisswenger, SK Howell, RM O'Dell, ME … - Diabetes Care, 2001 - Am Diabetes Assoc RESULTS—Treatment with insulin lispro resulted in a highly significant
reduction in PPGEs relative to the regular insulin–treated group (P = 0.0005).
However, HbA 1c levels were similar in the two groups, and no relationship ... Cited by 68 - Related articles - BL Direct - All 9 versions
J Berlanga, D Cibrian, I Guill# x00c9n, F … - Clinical Science, 2005 - submit.clinsci.org Increased formation of MG (methylglyoxal) and related protein glycation in
diabetes has been linked to the development of diabetic vascular complications.
Diabetes is also associated with impaired wound healing. In the present ... Cited by 24 - Related articles - Cached - All 10 versions
W Che, M Asahi, M Takahashi, H Kaneto, A … - Journal of Biological Chemistry, 1997 - ASBMB Methylglyoxal (MG) and 3-deoxyglucosone (3-DG), reactive dicarbonyl metabolites
in the glyoxalase system and glycation reaction, respectively, selectively
induced heparin-binding epidermal growth factor (HB-EGF)-like growth factor ... Cited by 66 - Related articles - BL Direct - All 5 versions
P Beisswenger, S Howell, R Nelson, M Mauer … - Biochemical Society Transactions, 2003 - bst.portlandpress.com The factors responsible for variable susceptibility to diabetic nephropathy are
not clear. According to the non-enzymatic glycation hypothesis, diabetes-related
tissue damage occurs due to a complex mixture of toxic products, including ... Cited by 49 - Related articles - Cached - BL Direct - All 9 versions
A Lapolla, R Flamini, AD Vedova, A Senesi, R … - Clinical Chemistry and Laboratory Medicine, 2003 - reference-global.com Determination of glyoxal and methylglyoxal levels in plasma is of great
interest, since it allows us to evalu- ate oxidation processes occurring in
glycated proteins. A method based on a simple derivatization procedure ... Cited by 57 - Related articles - BL Direct - All 7 versions
I Nemet, Z Turk, L Duvnjak, N Car, L Varga- … - Clinical biochemistry, 2005 - Elsevier Methylglyoxal was, in parallel, analyzed in the whole blood and the plasma of
the same individual. Significantly higher concentrations were measured in plasma
samples of both, patients with diabetes (n = 41) (742 ± 141 vs. 409 ± 131 ... Cited by 16 - Related articles - All 4 versions
M Fukunaga, S Miyata, BF Liu, H Miyazaki, Y … - Biochemical and Biophysical Research …, 2004 - Elsevier The formation of glucose-derived methylglyoxal (MG), a highly reactive
dicarbonyl compound, is accelerated under diabetic conditions. We examined
whether MG was capable of inducing apoptosis in Schwann cells (SCs), since ... Cited by 31 - Related articles - All 5 versions
PJ Beisswenger, SK Howell, K Smith, BS … - BBA-Molecular Basis of Disease, 2003 - Elsevier Methylglyoxal (MG) may be an important cause of diabetic complications. Its
primary source is dihydroxyacetone phosphate (DHAP) whose levels are partially
controlled by glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Using a ... Cited by 39 - Related articles - All 4 versions
- ►nrc-cnrc.gc.ca [PDF] L Wu - Canadian journal of physiology and pharmacology, 2005 - article.pubs.nrc-cnrc.gc.ca Abstract: Methylglyoxal (MG), a highly reactive metabolite of glucose, causes
non-enzymatic glycation of proteins to form irreversible advanced glycation
endproducts (AGEs). The present study investigated whether methylglyoxal ... Cited by 24 - Related articles - All 8 versions
- ►cnfindpark.cn M Negrean, A Stirban, B Stratmann, T … - American Journal of Clinical Nutrition, 2007 - ajcn.cnfindpark.cn Design: Twenty inpatients with T2DM [ (±SEM) age: 55.4 ± 2.2 y; glycated
hemoglobin: 8.8 ± 0.5%] were investigated. In a randomized crossover design,
the effects of a low-AGE (LAGE) and high-AGE (HAGE) meal on macrovascular ... Cited by 49 - Related articles - BL Direct - All 7 versions
