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Scholar Results 1 - 10 of about 101 related to Brändle: Diminished insulin secretory response to glucose but normal insulin and glucagon.... (0.09 sec) 

Diminished insulin secretory response to glucose but normal insulin and glucagon …

- diabetesjournals.org
M Brändle, R Lehmann, FE Maly, C Schmid, GA … - Diabetes care, 2001 - Am Diabetes Assoc
RESULTS—The glucose disappearance constant (K g ) value (mean ± SEM 0.61 ± 0.04 vs. 1.1
± 0.04, P = 0.0002) as well as the acute insulin response to glucose (area under the curve
[AUC] 0–10 min, 77.7 ± 50.7 vs. 1,352.3 ± 191.5 pmol/l, P = 0.0004) were decreased in all ...
Cited by 12 - Related articles - BL Direct - All 5 versions

[PDF] Michael Brandle, MD Roger Lehmann, MD


FE Maly - Diabetes Care, 2001 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS — The function of - and -cells was assessed in all five
siblings carrying the mitochondrial tRNA Leu(UUR) gene mutation at position 3243 and compared
with six sex-, age-, and weight-matched control subjects. Insulin and C-peptide responses ...
Related articles

Insulin secretion and insulin sensitivity are normal in non-diabetic subjects from …


DJ Holmes-Walker, GM Ward, SC Boyages - Diabetic Medicine, 2001 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 4 - Related articles - BL Direct - All 4 versions

[beta]-Cell Function in Individuals Carrying the Mitochondrial tRNA Leu (UUR) …


JE Salles, TS Kasamatsu, SA Dib, RS Moisés - Pancreas, 2007 - journals.lww.com
Skip Navigation Links Home > January 2007 - Volume 34 - Issue 1 > [beta]-Cell Function in Individuals
Carrying the Mitochondri... ... From the Division of Endocrinology, Department of Medicine, Federal
University of São Paulo, São Paulo, SP, Brazil. ... This study was supported by a grant ...
Cited by 5 - Related articles - BL Direct - All 2 versions

Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, …


JK Sandhu, C Sodja, K Mcrae, Y Li, P … - Biochemical …, 2005 - pubmedcentral.nih.gov
Reactive nitrogen and oxygen species (O 2 •− , H 2 O 2 , NO • and ONOO − ) have been strongly
implicated in the pathophysiology of neurodegenerative and mitochondrial diseases. In the present
study, we examined the effects of nitrosative and/or nitrative stress generated by ...
Cited by 7 - Related articles - BL Direct - All 8 versions

A novel 7301-bp deletion in mitochondrial DNA in a patient with Kearns-Sayre …


CEM De Block, IH De Leeuw, JA Maassen, … - Experimental and …, 2004 - thieme-connect.com
We report a 27-year-old woman with a form of mitochondrial myopathy including chronic progressive
external opthalmoplegia, retinal pigmentary dystrophy, cerebellar ataxia, and cardiac conduction
block (Kearns-Sayre syndrome). At age 13 years a cardiac pacemaker was implanted. ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Insulin resistance associated with maternally inherited diabetes and deafness* 1


SSP Gebhart, JM Shoffner, D Koontz, A Kaufman, D … - Metabolism, 1996 - Elsevier
Maternally inherited diabetes and deafness (MIDD) is a form of diabetes associated with mutation
of mitochondrial DNA (mtDNA) that occurs in 1% to 2% of individuals with diabetes. Understanding
the clinical course and abnormalities in insulin secretion and action in affected individuals ...
Cited by 28 - Related articles - BL Direct - All 6 versions

Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with …


G Velho, MM Byrne, K Clement, J Sturis, ME Pueyo, H … - Diabetes, 1996 - Am Diabetes Assoc
An A-to-G transition in the mitochondrial tRNALeu(UUR) gene at base pair 3243 has been shown
to be associated with the maternally transmitted clinical phenotype of NIDDM and sensorineural
hearing loss in white and Japanese pedigrees. We have detected this mutation in 25 of ...
Cited by 76 - Related articles - All 4 versions

Mitochondrial activation and the pyruvate paradox in a human cell line

- unige.ch [PDF] 
PBM de Andrade, M Casimir, P Maechler - FEBS letters, 2004 - Elsevier
Pyruvate promotes hyperpolarization of the inner mitochondrial membrane. However, in isolated
mitochondria, pyruvate could participate in a futile cycle leading to mitochondrial
depolarization. Here, we investigated this paradox in intact human cells by measuring ...
Cited by 10 - Related articles - All 6 versions

β-cell loss and glucose induced signalling defects in diabetes mellitus caused by …


Y Oka, H Katagiri, H Ishihara, T Asano, T Kobayashi, M … - Diabetic medicine, 1996 - cat.inist.fr
β-cell loss and glucose induced signalling defects in diabetes mellitus caused by mitochondrial
tRNALeu (UUR)  gene mutation. Y OKA, H KATAGIRI, H ISHIHARA, T ASANO, T
KOBAYASHI, M KIKUCHI Diabetic medicine 13, 98-102, Blackwell, 1996. ...
Cited by 11 - Related articles - BL Direct - All 2 versions


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