- ►diabetesjournals.org S Yamada, Y Motohashi, T Yanagawa, T Maruyama … - Diabetes care, 2001 - Am Diabetes Assoc OBJECTIVE—The majority of type 1 diabetes is considered to be autoimmune with, for the most
part, abrupt development. However, type 1 diabetes with slow onset, or the so-called slowly progressive
type 1 diabetes or latent autoimmune diabetes in adults, has been recently recognized ... Cited by 26 - Related articles - BL Direct - All 5 versions
MT Malecki, T Klupa, DK Moczulski, JJ … - Experimental and …, 2003 - thieme-connect.com It has recently been shown that mutations in BETA2/NeuroD1 are responsible for the development
of type 2 diabetes mellitus (T2DM) in Caucasians. This gene is located near the IDDM7 region
and one of its amino acid polymorphisms, Ala45Thr, has been associated with type 1 ... Cited by 8 - Related articles - BL Direct - All 5 versions
S Dupont, C Dina, EH Hani, P Froguel - Diabetes & metabolism, 1999 - cat.inist.fr BETA 2/NEUROD 1 est un facteur de transcription essentiel au développement des îlots pancréatiques
ainsi qu'à l'expression du gène de l'insuline. Le locus BETA 2/NEUROD 1 est situé sur le chromosome
2 humain(bande 2 q 32), région coïncidant avec un locus de prédisposition au diabète de ... Cited by 20 - Related articles - All 2 versions
FK Kavvoura, JPA Ioannidis - Human genetics, 2005 - Springer Abstract A meta-analysis assessed whether the Ala45Thr polymorphism of the neurogenic
differentia- tion 1 (NEUROD1) gene is associated with increased risk of diabetes mellitus type
1 (T1D) or type 2 (T2D). Fourteen case-control studies were analyzed, including genotype ... Cited by 14 - Related articles - All 4 versions
A Vella, JMM Howson, BJ Barratt, RCJ Twells, HE … - Diabetes, 2004 - Am Diabetes Assoc Variation in genes necessary for normal functioning and development of β-cells, eg,
NEUROD1, which encodes a transcription factor for the insulin gene and is important in β-cell
development, causes maturity-onset diabetes of the young. Some studies have reported ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] I Iwata, S Nagafuchi, H Nakashima, S Kondo, T Koga, Y … - Diabetes, 1999 - Am Diabetes Assoc N euro D / BE TA2, a transcription factor of the insulin gene, also plays an important role in the
development of pan- creatic -cells. Recently, the NeuroD/BETA2 gene has been mapped to the
long arm of human chromosome 2 (2q32) where the IDDM 7 gene has previously been ... Cited by 61 - Related articles - BL Direct - All 6 versions
- ►lmg.cz [PDF] O Cinek, P Dřevı́nek, Z Šumnı́k, B Bendlová, P … - Diabetes research and …, 2003 - Elsevier Association of the NEUROD Ala45Thr polymorphism with Type 1 diabetes mellitus (DM) has
been found in some but not all populations. We performed a study on the association of two NEUROD
exon 2 polymorphisms, the Ala45Thr and the Pro197His, with childhood-onset Type 1 DM ... Cited by 9 - Related articles - All 8 versions
- ►diabetesjournals.org [PDF] L Hansen, JN Jensen, S Urioste, HV Petersen, F Pociot … - Diabetes, 2000 - Am Diabetes Assoc Mutations in the NeuroD/BETA2 gene have been shown to associate with type 2 diabetes. In
the present study, we examined mutations in the NeuroD/BETA2 gene for association with either
type 1 or 2 diabetes. Three vari- ants were identified in patients with type 2 diabetes: ... Cited by 30 - Related articles - BL Direct - All 5 versions
M Mochizuki, S Amemiya, K Kobayashi, K … - Diabetes research and …, 2002 - Elsevier Recently Iwata et al. reported that the polymorphism in NeuroD exon 2(Ala45Thr) was associated
with adult-onset Type 1 diabetes in Japanese. Furthermore, the mutations in the NeuroD as a
regulator of insulin transcription have been reported to result in Type 2 diabetes. We, ... Cited by 13 - Related articles - All 5 versions
T Awata, K Inoue, I Inoue, T Abe, H Takino, Y … - Diabetes research and …, 2000 - Elsevier To evaluate the role of the Ala45Thr variant of BETA2/NEUROD1 in the development of type
1 or type 2 diabetes, we studied a Japanese population consisting of 383 control subjects, 234
type 1 diabetes patients and 160 type 2 diabetes patients. Both genotypewise and ... Cited by 11 - Related articles - All 5 versions
