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Scholar Results 1 - 10 of about 101 related to Vinik: Platelet dysfunction in type 2 diabetes. (0.08 sec) 

Platelet dysfunction in type 2 diabetes

- Free from Publisher
AI Vinik, T Erbas, TS Park, R Nolan, GL … - Diabetes Care, 2001 - Am Diabetes Assoc
Insulin resistance is a uniform finding in type 2 diabetes, as are abnormalities
in the microvascular and macrovascular circulations. These complications are
associated with dysfunction of platelets and the neurovascular unit. ...
Cited by 249 - Related articles - BL Direct - All 5 versions

Platelet hyperactivity and abnormal Ca2+ homeostasis in diabetes mellitus

- physiology.org
Y Li, V Woo, R Bose - American Journal of Physiology- Heart and Circulatory …, 2001 - Am Physiological Soc
We sought to determine the mechanisms for hyperactivity and abnormal platelet Ca
2+ homeostasis in diabetes. The glycosylated Hb (HbA 1c ) level was used as an
index of glycemic control. Human platelets were loaded with Ca- green-fura ...
Cited by 95 - Related articles - BL Direct - All 4 versions

Regulation of protein kinase C by short term hyperglycaemia in human platelets in vivo and in …


R Assert, G Scherk, A Bumbure, V Pirags, H … - Diabetologia, 2001 - Springer
Aims/hypothesis. Postprandial hyperglycaemia car- ries an increased risk of
macrovascular disease even without Type II (non-insulin-dependent) diabetes
mellitus. Chronic hyperglycaemia activates protein kinase C (PKC) in vitro ...
Cited by 63 - Related articles - BL Direct - All 4 versions

The platelet in diabetes

- Free from Publisher
JA Colwell, RW Nesto - Diabetes Care, 2003 - Am Diabetes Assoc
Accelerated atherosclerosis and the increased risk of thrombotic vascular events
in diabetes may result from dyslipidemia, endothelial dysfunction, platelet
hyperreactivity, an impaired fibrinolytic balance, and abnormal blood flow. ...
Cited by 129 - Related articles - BL Direct - All 5 versions

Diabetes accelerates smooth muscle accumulation in lesions of atherosclerosis


LA Suzuki, M Poot, RG Gerrity, KE Bornfeldt - Diabetes, 2001 - Am Diabetes Assoc
In combination with other factors, hyperglycemia may cause the accelerated
progression of atherosclerosis in people with diabetes. Arterial smooth muscle
cell (SMC) proliferation and accumulation contribute to formation of ...
Cited by 117 - Related articles - BL Direct - All 5 versions

Platelet activation in type 2 diabetes mellitus


P Ferroni, S Basili, A Falco, G Davi - Journal of Thrombosis and Haemostasis, 2004 - interscience.wiley.com
Summary. The abnormal metabolic state that accompanies diabetes renders arteries
susceptible to atherosclerosis, being capable of altering the functional
properties of multiple cell types, including endothelium and platelets. In ...
Cited by 104 - Related articles - BL Direct - All 3 versions

Diabetes mellitus A hypercoagulable state


ME Carr - Journal of Diabetes and its Complications, 2001 - Elsevier
Eighty percent of patients with diabetes mellitus die a thrombotic death.
Seventy-five percent of these deaths is due to cardiovascular complications, and
the remainder is due to cerebrovascular events and peripheral vascular ...
Cited by 333 - Related articles - BL Direct - All 9 versions

Hyperglycemia-induced thrombin formation in diabetes. The possible role of oxidative stress …


A Ceriello, R Giacomello, G Stel, E Motz, C … - Diabetes, 1995 - Am Diabetes Assoc
Diabetes is characterized by the existence of a thrombosis-prone condition,
possibly related to hyperglycemia. However, the mechanism linking hyperglycemia
to the activation of the coagulation cascade is still unclear. It has been ...
Cited by 144 - Related articles - BL Direct - All 4 versions

Immunohistochemical and morphometric evaluations of coronary atherosclerotic plaques …


H Fukumoto, Z Naito, G Asano, T Aramaki - Journal of atherosclerosis and thrombosis, 1998 - ncbi.nlm.nih.gov
Immunohistochemical and morphometrical studies were performed to elucidate the
specificity of atherosclerosis in the descending branch (the segments 5 and 6)
of the left coronary artery associated with acute myocardial infarction ...
Cited by 56 - Related articles

Influence of insulin and of insulin resistance on platelet and vascular smooth muscle cell …


M Trovati, G Anfossi - Journal of diabetes and its complications, 2002 - Elsevier
In this short review, we present the main results obtained in our laboratory in
the last 15 years concerning the influence exerted by insulin on platelets and
human vascular smooth muscle cells (VSMCs). In particular, we discuss: (i) ...
Cited by 58 - Related articles - BL Direct - All 7 versions


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