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A diabetes outcome progression trial (ADOPT)

- diabetesjournals.org
G Viberti, SE Kahn, DA Greene, WH Herman, B … - Diabetes Care, 2002 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—A Diabetes Outcome Progression Trial (ADOPT) is a randomized,
double-blind, parallel-group study consisting of a screening visit, a 4-week placebo run-in, a
4-year treatment period, and an ...
Cited by 168 - Related articles - BL Direct - All 14 versions

Rosiglitazone monotherapy is effective in patients with type 2 diabetes

- endojournals.org
HE Lebovitz, JF Dole, R Patwardhan, EB … - Journal of Clinical …, 2001 - Endocrine Soc
This study evaluated the efficacy and safety of rosiglitazone monotherapy in patients with type 2
diabetes. After a 4-week placebo run-in period, 493 patients with type 2 diabetes were randomized to
receive rosiglitazone [2 or 4 mg ...
Cited by 415 - Related articles - BL Direct - All 5 versions

Rosiglitazone, but not glyburide, reduces circulating proinsulin and the proinsulin: …

- endojournals.org
SA Smith, LE Porter, N Biswas, MI Freed - Journal of Clinical …, 2004 - Endocrine Soc
An elevation in the ratio of proinsulin (PI) to immunoreactive insulin (IRI) is inversely related to
ß-cell function in type 2 diabetes, and increased PI is an independent risk factor for coronary
heart disease. An objective of the ...
Cited by 38 - Related articles - All 5 versions

Effect of metformin and rosiglitazone combination therapy in patients with type 2 …

- zhaoys.com [PDF] 
V Fonseca, J Rosenstock, R Patwardhan, A Salzman - Jama, 2000 - Am Med Assoc
Context Most antidiabetic agents target only 1 of several underlying causes of diabetes. The
complementary actions of the antidiabetic agents metformin hydrochloride and rosiglitazone maleate
may maintain optimal glycemic ...
Cited by 520 - Related articles - BL Direct - All 8 versions

Evaluation of liver function in type 2 diabetic patients during clinical trials

- diabetesjournals.org
HE Lebovitz, M Kreider, MI Freed - Diabetes Care, 2002 - Am Diabetes Assoc
OBJECTIVE—Troglitazone treatment has been associated with idiosyncratic hepatic reaction leading
to hepatic failure and death in some patients. This raises questions regarding whether all
thiazolidinediones or peroxisomal ...
Cited by 150 - Related articles - BL Direct - All 8 versions

Rationale, design and recruitment characteristics of a large, simple international …


HC Gerstein, S Yusuf, R Holman, J Bosch, J Pogue - Diabetologia, 2004 - ncbi.nlm.nih.gov
AIMS/HYPOTHESIS: Diabetes is a rapidly rising independent risk factor for atherosclerosis and
serious illness. This risk can be reduced by lifestyle changes and/or various drugs. Novel therapies
to prevent diabetes, as well as new ...
Cited by 71 - Related articles

Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in …

- infodiabetes.it [PDF] 
PD Home, SJ Pocock, H Beck-Nielsen, R Gomis, M … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 1726–1735 DOI 10.1007/s00125-005-1869-1 ARTICLE PD Home . SJ
Pocock . H. Beck-Nielsen . R. Gomis . M. Hanefeld . H. Dargie . M. Komajda . J. Gubb . N. Biswas .
NP Jones Rosiglitazone Evaluated for Cardiac Outcomes and Regulation ...
Cited by 147 - Related articles - BL Direct - All 5 versions

The impact of pioglitazone on glycemic control and atherogenic dyslipidemia in …


S Rosenblatt, B Miskin, NB Glazer, MJ Prince, … - Coronary Artery …, 2001 - journals.lww.com
Results Compared with placebo, pioglitazone ( ) ( significantly P = 0.0001 reduced HbA y1.37% 1c ) (
) points , FPG y3.19mmol/l;y57.5mg/dl , fasting ( ) C-peptide y0.076"0.022 nmol/l , and fasting
insulin ( ) y11.88"4.70 pmol/l . ...
Cited by 132 - Related articles - BL Direct - All 2 versions

[CITATION] Effect of combination therapy with rosiglitazone and glibenclamide on PAI-1 …


M Freed, D Fuell, L Menci, M Heise, B Goldstein - Diabetologia, 2000
Cited by 67 - Related articles

Effects of rosiglitazone alone and in combination with atorvastatin on the metabolic …


MI Freed, R Ratner, SM Marcovina, MM Kreider, N … - The American journal of …, 2002 - Elsevier
This study evaluated the effects of rosiglitazone therapy on lipids and the efficacy and safety of
rosiglitazone in combination with atorvastatin in patients with type 2 diabetes mellitus.
Three-hundred thirty-two patients ...
Cited by 170 - Related articles - All 5 versions


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