- ►diabetesjournals.org Y Oikawa, A Shimada, S Yamada, Y Motohashi, Y … - Diabetes care, 2002 - Am Diabetes Assoc OBJECTIVE—Natural killer T-cells (NKT cells) are believed to play an important role in the
regulation of immune response, and a numerical and functional deficit of NKT cells has been reported
to be associated with the ... Cited by 28 - Related articles - BL Direct - All 5 versions
SP Berzins, K Kyparissoudis, DG Pellicci, … - Immunology and cell …, 2004 - interscience.wiley.com Summary In the diabetes-prone NOD mouse, there is a proven association between a systemic deficiency
of NKT cells and the onset of type 1 diabetes. Numerous reports of similar defects within the NKT
cell compartment of human type 1 ... Cited by 30 - Related articles - BL Direct - All 5 versions
Y Oikawa, A Shimada, S Yamada, Y Motohashi, Y … - Diabetes Care, 2002 - Am Diabetes Assoc OBJECTIVE — Natural killer T-cells (NKT cells) are believed to play an important role in the
regulation of immune response, and a numerical and functional deficit of NKT cells has been reported
to be associated with the ... Cited by 2 - Related articles
M Mizuno, M Masumura, C Tomi, A Chiba, S Oki, T … - Journal of Autoimmunity, 2004 - Elsevier Non-obese diabetic (NOD) mice develop diabetes mediated by pathogenic T-helper type 1 (Th1) cells.
Vα14 Natural killer (NKT) cells are a unique lymphocyte subtype implicated in the regulation of
autoimmunity and a good source of ... Cited by 37 - Related articles - All 4 versions
- ►nih.gov PT Lee, A Putnam, K Benlagha, L Teyton, … - Journal of Clinical …, 2002 - Am Soc Clin Investig Defects in IL-4–producing CD1d-autoreactive NKT cells have been implicated in numerous
Th1-mediated autoimmune diseases, including diabetes, multiple sclerosis, rheumatoid arthritis,
lupus, and systemic sclerosis. ... Cited by 132 - Related articles - BL Direct - All 9 versions
- ►jimmunol.org SC Kent, Y Chen, SM Clemmings, V Viglietta, … - The Journal of …, 2005 - Am Assoc Immnol Altered frequency and function of peripheral invariant NKT (iNKT) cells have been implicated in the
regulation of murine and human type 1a diabetes. To examine regulatory cells from the site of
drainage of autoinflammatory tissue ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►cell.com L Beaudoin, V Laloux, J Novak, B Lucas, A Lehuen - Immunity, 2002 - Elsevier To determine the precise regulatory effect of NKT cells on CD4 + T cells involved in autoimmune
diabetes, we developed an in vivo model in which transferred naive transgenic T cells are stimulated
by their antigen in the presence or ... Cited by 83 - Related articles - BL Direct - All 7 versions
- ►jimmunol.org J Novak, L Beaudoin, T Griseri, A … - The Journal of Immunology, 2005 - Am Assoc Immnol NKT cells are potent regulatory T cells that prevent the development of several autoimmune diseases.
Analysis of NKT cell regulatory function in the NOD mouse has revealed that NKT cells inhibit the
development of type 1 diabetes by ... Cited by 29 - Related articles - All 5 versions
- ►oxfordjournals.org M Araki, T Kondo, JE Gumperz, MB Brenner, S … - International …, 2003 - Jpn Soc Immunol Although CD1d-restricted NKT cells have been implicated as a participant in the regulatory mechanism
of autoimmune diseases, it remains unclear how they would regulate human autoimmune diseases such as
multiple sclerosis (MS). ... Cited by 70 - Related articles - BL Direct - All 5 versions
Y Oikawa, A Shimada, S Yamada, Y … - ANNALS-NEW …, 2003 - interscience.wiley.com Abstract: A numerical and functional deficit of natural killer T (NKT) cells has been reported to be
associated with the pathogenesis of Caucasian patients with type 1 diabetes. However, a conflicting
finding of a higher frequency of ... Cited by 6 - Related articles - BL Direct - All 5 versions
