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Scholar Results 1 - 10 of about 101 related to Simó: Deficit of somatostatin-like immunoreactivity in the vitreous fluid of diabetic patients. (0.10 sec) 

Deficit of somatostatin-like immunoreactivity in the vitreous fluid of diabetic patients


R Simó, A Lecube, L Sararols, J García- … - Diabetes Care, 2002 - Am Diabetes Assoc
RESULTS—SLI in the vitreous fluid was significantly lower in diabetic patients
than in the control group (68 ± 18.7 vs. 193.6 ± 30.8 pg/ml, P < 0.01). The
vitreous SLI-to-plasma SLI ratio was strikingly higher in nondiabetic ...
Cited by 18 - Related articles - BL Direct - All 5 versions

Somatostatin Molecular Variants in the Vitreous Fluid

- diabetesjournals.org
C Hernández, E Carrasco, R Casamitjana, R … - Diabetes Care, 2005 - Am Diabetes Assoc
OBJECTIVE—There is growing evidence to indicate that somatostatin could be
added to the list of natural antiangiogenic factors that exist in the vitreous
fluid. In addition, a deficit of intravitreous somatostatin-like ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Deficit of somatostatin in the vitreous fluid of patients with diabetic macular edema


R Simó, E Carrasco, A Fonollosa, J García- … - Diabetes care, 2007 - Am Diabetes Assoc
Although diabetic macular edema (DME) is the main cause of visual loss in type 2
diabetic patients (1), its pathogenic mechanisms have been much less studied
than proliferative diabetic retinopathy (PDR). The production of both ...
Cited by 9 - Related articles - BL Direct - All 5 versions

The therapeutic problem of proliferative diabetic retinopathy: targeting somatostatin …


MI Davis, SH Wilson, MB Grant… - Hormone and Metabolic Research, 2001 - thieme-connect.com
Clinical management of proliferative diabetic retinopathy has changed very
little in the last 5 decades, relying primarily on laser ablation of the retinal
vasculature. Several lines of clinical and experimental evidence suggest ...
Cited by 26 - Related articles - BL Direct - All 4 versions

[PDF] Somatostatin and somatostatin receptors in retinal diseases


PM Van Hagen, GS Baarsma, CM Mooy, EM … - EUROPEAN JOURNAL OF ENDOCRINOLOGY- …, 2000 - EFES
Introduction Somatostatin is a small neuropeptide that is produced in the
central nervous system, where it acts as a neurotransmitter. This neuropeptide
also has an important role in the neuroendocrine system as an inhibitor of ...
Cited by 39 - Related articles - BL Direct - All 13 versions

Octreotide prevents growth factor-induced proliferation of bovine retinal endothelial cells …

- endocrinology-journals.org [PDF] 
A Baldysiak-Figiel, GK Lang, J Kampmeier, … - Journal of Endocrinology, 2004 - Soc Endocrinology
Ocular diseases such as proliferative diabetic retinopathy are the major cause
of blindness in industrialized countries. The main pathologic features of these
diseases are hypoxia and overproduction of growth factors resulting in ...
Cited by 22 - Related articles - BL Direct - All 6 versions

Strategies for blocking angiogenesis in diabetic retinopathy: from basic science to clinical …


C Hernández, R Simó - Expert Opinion in Investigational Drugs, 2007 - informahealthcare.com
Proliferative diabetic retinopathy (PDR) demands both more effective and less
expensive biologically based treatments. Our understanding of the
pathophysiology of the disease is increasing as new biochemical pathways ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Somatostatin inhibits IGF-1 mediated induction of VEGF in human retinal pigment epithelial …


JW Sall, DD Klisovic, MS O'Dorisio, SE Katz - Experimental eye research, 2004 - Elsevier
Neovascularization stimulated by IGF-1 mediated induction of vascular
endothelial growth factor (VEGF) is one of the leading causes of blindness in
humans. It plays a central role in the pathogenesis of proliferative ...
Cited by 32 - Related articles - All 3 versions

Anti-Inflammatory Effects of Somatostatin Analogs on Zymosan-Induced Earlobe …


I Kurnatowska, M Pawlikowski - Neuroimmunomodulation, 2000 - content.karger.com
The aim of the present study was the estimation of the anti-inflammatory effects
of the somatostatin analogs, octreotide (OCT) and vapreotide (RC-160), in
zymosan-induced mice ear inflammation and to compare their effects with ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy


R Simo, E Carrasco, M Garcia-Ramirez, C … - Current Diabetes Reviews, 2006 - ingentaconnect.com
Abstract: Diabetic retinopathy continues to be the leading cause of legal
blindness among working-age individuals. The earliest histological features of
diabetic retinopathy include neuroretinal damage, capillary basement ...
Cited by 34 - Related articles - BL Direct - All 2 versions


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