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Scholar Results 1 - 10 of about 101 related to Stride: Intrauterine hyperglycemia is associated with an earlier diagnosis of diabetes in.... (0.10 sec) 

Intrauterine hyperglycemia is associated with an earlier diagnosis of diabetes in HNF-1α …

- Free from Publisher
A Stride, M Shepherd, TM Frayling, MP Bulman, … - Diabetes Care, 2002 - Am Diabetes Assoc
OBJECTIVE—In animals, experimentally induced maternal hyperglycemia during
pregnancy results in hyperglycemic offspring. Similarly, Pima Indian offspring
with mothers who are diabetic at the time of pregnancy have increased risk ...
Cited by 42 - Related articles - BL Direct - All 6 versions

Determinants of the Development of Diabetes (Maturity-Onset Diabetes of the Young-3) in …

- diabetesjournals.org
T Klupa, JH Warram, A Antonellis, M … - Diabetes Care, 2002 - Am Diabetes Assoc
RESULTS—HNF-1α mutations cosegregated with diabetes in only 13 families, all
with a mean age at onset <35 years. Insulin secretion was diminished or absent
in mutation carriers (n = 101), and diabetes developed in 65% by age 25 ...
Cited by 37 - Related articles - BL Direct - All 5 versions

Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential …

- oxfordjournals.org
LW Harries, S Ellard, A Stride… - Human Molecular Genetics, 2006 - Oxford Univ Press
The generation of multiple transcripts by mRNA processing has the potential to
moderate differences in gene expression both between tissues and at different
stages of development. Where gene function is compromised by mutation, the ...
Cited by 20 - Related articles - BL Direct - All 6 versions

High Prevalence of Type 2 Diabetes and Pre-Diabetes in Adult Offspring of Women With …

- Free from Publisher
TD Clausen, ER Mathiesen, T Hansen, O … - Diabetes Care, 2008 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—The glucose tolerance status following a 2-h 75-g
oral glucose tolerance test (OGTT) was evaluated in 597 subjects, primarily
Caucasians, aged 18–27 years. They were subdivided into four groups ...
Cited by 20 - Related articles - BL Direct - All 4 versions

Low acute insulin secretory responses in adult offspring of people with early onset type 2 …

- diabetesjournals.org
JF Gautier, C Wilson, C Weyer, D Mott, WC … - Diabetes, 2001 - Am Diabetes Assoc
The offspring of Pima Indians with early onset type 2 diabetes are at high risk
for developing diabetes at an early age. This risk is greater among those whose
mothers were diabetic during pregnancy. To define the metabolic ...
Cited by 60 - Related articles - BL Direct - All 4 versions

Maternal diabetes alters birth weight in glucokinase-deficient (MODY2) kindred but has no …


G Velho, AT Hattersley, P Froguel - Diabetologia, 2000 - Springer
Maternal intrauterine environment and fetal geno- types influence size at birth
and birth weight. It is well established that poor maternal nutrition is asso-
ciated with reduced intrauterine growth and that ma- ternal hyperglycaemia ...
Cited by 40 - Related articles - BL Direct - All 3 versions

Effect of a diabetic environment in utero on predisposition to type 2 diabetes


E Sobngwi, P Boudou, F Mauvais-Jarvis, H … - The Lancet, 2003 - Elsevier
There was no difference between the groups with respect to percent body fat and
insulin sensitivity. Five of the 15 exposed participants, but none of the
controls had impaired glucose tolerance (p=0·02). Early insulin secretion ...
Cited by 100 - Related articles - All 8 versions

On possible genetic and epigenetic modes of diabetes transmission.


G Dörner, A Mohnike, E Steindel - Endokrinologie, 1975 - ncbi.nlm.nih.gov
1 In 4058 diabetics, an inverse relation (negative semilogarithmic correlation)
was found between the age of onset and the familial aggregation of diabetes
mellitus (P less than 0.01). Hence, juvenile (especially infantile) ...
Cited by 18 - Related articles

Genetic cause of hyperglycaemia and response to treatment in diabetes


ER Pearson, BJ Starkey, RJ Powell, FM … - The Lancet, 2003 - Elsevier
Type 2 diabetes shows evidence of underlying heterogeneity. No studies have
assessed whether different causes for diabetes change the response to oral
hypoglycaemic therapy. In a few cases, patients with diabetes caused by ...
Cited by 132 - Related articles - All 4 versions

Long-term follow-up of infants of mothers with type 1 diabetes: evidence for hereditary and …

- diabetesjournals.org [PDF] 
PA Weiss, HS Scholz, J Haas, KF Tamussino, … - Diabetes Care, 2000 - Am Diabetes Assoc
Study subjects and methods Between 1982 and 1991, 210 viable new- borns were
delivered of mothers with type 1 diabetes at our institution. We considered the
mothers to have type 1 diabetes because they had acute onset of insulin- ...
Cited by 53 - Related articles - BL Direct - All 6 versions


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