- Free from Publisher M Tamminen, J Westerbacka, S Vehkavaara, H … - Diabetes Care, 2002 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Insulin normally acutely decreases central
systolic pressure by decreasing wave reflection in vivo. This effect occurs
before any changes in peripheral vascular resistance or heart rate under ... Cited by 20 - Related articles - BL Direct - All 5 versions
- ►endojournals.org J Westerbacka, A Seppala-Lindroos, H Yki- … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc Arterial stiffness has recently been recognized as an important cardiovascular
risk marker. Physiological concentrations of insulin diminish wave reflection in
the aorta in vivo. This decreases central blood pressure augmentation and ... Cited by 35 - Related articles - BL Direct - All 5 versions
MK Tamminen, J Westerbacka, S Vehkavaara, … - European journal of clinical investigation, 2003 - pt.wkhealth.com Supported by grants from the Academy of Finland (HY, JW), Liv och Hälsa (HY)
and the Sigrid Juselius (HY) and Novo Nordisk (HY) Foundations. ... Department
of Medicine, Division of Diabetes, University of Helsinki, Helsinki, ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org J Westerbacka, I Wilkinson, J Cockcroft, T … - Hypertension, 1999 - Am Heart Assoc Abstract—Epidemiological data suggest that insulin may have direct effects on
large-vessel function, but thus far insulin has only been shown, after prolonged
infusions, to slowly decrease peripheral vascular resistance by increasing ... Cited by 92 - Related articles - BL Direct - All 7 versions
J Westerbacka, M Tamminen, J Cockcroft, H … - European journal of clinical investigation, 2004 - pt.wkhealth.com Background: Individuals whose platelets are resistant to the antiaggregatory
effects of insulin in vitro are also resistant to the antiaggregatory effects of
nitroglycerin (GTN). We have previously shown that insulin acutely ... Cited by 8 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org [PDF] J Westerbacka, S Vehkavaara, R Bergholm, I … - Diabetes, 1999 - Am Diabetes Assoc We tested the hypothesis that insulin has effects on large artery stiffness in
addition to its slow vasodilatory e ffect on resistance vessels in skeletal
muscle, and whether such an effect might be altered in obesity. Eight ... Cited by 87 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org J Westerbacka, A Uosukainen, S Makimattila, … - Hypertension, 2000 - Am Heart Assoc Abstract—Normal insulin action in vivo involves a decrease in stiffness of
large arteries (a decrease in aortic pressure augmentation). We determined
whether the ability of insulin to decrease arterial stiffness is altered in ... Cited by 38 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org J Westerbacka, R Bergholm, M Tiikkainen, H … - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc Methods and Results— Ten healthy men (age: 33±9 years [mean±SD]; BMI: 23±2
kg/m 2 ) were studied on two separate occasions in a double-blind, randomized,
crossover fashion. In each study, blood flow responses to intrabrachial ... Cited by 12 - Related articles - BL Direct - All 10 versions
J Westerbacka, E Leinonen, JT Salonen, R … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Type 2 diabetes is associated with a two- to
seven-fold increase in cardiovascular mor- bidity and mortality. The aim of this
study was to de- termine the relationships between intima–media thickness ... Cited by 15 - Related articles - BL Direct - All 5 versions
M Sandqvist, G Nyberg, A Hammarstedt, N … - Atherosclerosis, 2005 - Elsevier Ten non-diabetic male subjects with low adipocyte IRS-1 protein expression
(LIRS) were matched with 10 non-diabetic males with normal IRS-1 protein
expression (NIRS). Augmentation index (AIx) and time for reflection of ... Cited by 4 - Related articles - All 7 versions
