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Increased fructose concentrations in blood and urine in patients with diabetes

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T Kawasaki, H Akanuma, T Yamanouchi - Diabetes Care, 2002 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Serum and urinary fructose concentrations were
determined in healthy subjects (n = 23) and in nondiabetic (n = 23) and diabetic
patients (n = 26). Fructose was measured using our newly developed method, ...
Cited by 27 - Related articles - BL Direct - All 5 versions

Postprandial plasma fructose level is associated with retinopathy in patients with type 2 …


T Kawasaki, N Ogata, H Akanuma, T Sakai, H … - Metabolism, 2004 - Elsevier
The aim of the present study was to investigate the association of fructose on
microangiopathy in patients with diabetes. Postprandial plasma fructose
concentrations and postprandial plasma glucose concentrations were ...
Cited by 14 - Related articles - All 7 versions

Mannose, mannitol, fructose and 1, 5-anhydroglucitol concentrations measured by gas …


E Pitkänen - Clinica chimica acta, 1996 - Elsevier
Gas chromatography/mass fragmentography was applied to measure sugars in the
plasma of patients with diabetes mellitus (DM). The isotope-dilution technique
was used in the calculation of 1,5-anhydro- -glucitol (1,5-AG), whereas ...
Cited by 23 - Related articles - All 5 versions

Clinical usefulness of measuring urinary polyol excretion by gas-chromatography/mass- …


H Yoshii, H Uchino, C Ohmura, K Watanabe, … - Diabetes research and clinical practice, 2001 - Elsevier
Introduction: Decreased myo-inositol levels and increased activity of the polyol
pathway have been proposed to play a role in causing diabetic microvascular
complications. There are few clinical methods for examining the activity of ...
Cited by 12 - Related articles - All 9 versions

Fructose uptake in rat adipocytes: GLUT5 expression and the effects of streptozotocin- …


E Hajduch, F Darakhshan, HS Hundal - Diabetologia, 1998 - Springer
Summary Previous studies have shown that rat adi- pocytes possess the capacity
to take up fructose by a mechanism that is distinct from that involved in the
transport of glucose. In this investigation we report that rat adipocytes ...
Cited by 25 - Related articles - BL Direct - All 3 versions

Insulin regulates the expression of the GLUT5 transporter in L6 skeletal muscle cells


E Hajduch, GJ Litherland, S Turban, E Brot- … - FEBS letters, 2003 - Elsevier
Skeletal muscle, a primary insulin target tissue, expresses the GLUT5 fructose
transporter. Although insulin has no acute effect on GLUT5 expression and
function in muscle, we show here that long-term (24 h) insulin treatment of ...
Cited by 4 - Related articles - All 7 versions

Energy expenditure and substrate metabolism after oral fructose in patients with cirrhosis


YT Kruszynska, A Meyer-Alber, N Wollen, N … - Journal of hepatology, 1993 - Elsevier
There is little information on the metabolic response to ingested fructose in
patients with cirrhosis. Glucose kinetics, plasma lipid and blood lactate
levels, whole body substrate oxidation rates and energy expenditure were ...
Cited by 5 - Related articles - BL Direct - All 4 versions

Functional studies of human GLUT5: effect of pH on substrate selection and an analysis of …


S Kane, MJ Seatter, GW Gould - Biochemical and Biophysical Research …, 1997 - Elsevier
The adsorption of D-fructose within the lumen of the human small intestine is
thought to be mediated by the GLUT5 isoform of the human facilitative sugar
transporter family. This isoform has been expressed in oocytes and shown to ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Biochemical and functional characterization of the GLUT5 fructose transporter in rat skeletal …

- nih.gov [PDF] 
F Darakhshan, E Hajduch, S Kristiansen, EA … - Biochemical Journal, 1998 - pubmedcentral.nih.gov
Previous work has demonstrated that human skeletal muscle and adipose tissue
both express the GLUT5 fructose transporter, but to date the issue of whether
this protein is also expressed in skeletal muscle and adipose tissue of ...
Cited by 22 - Related articles - BL Direct - All 7 versions

フルクトース毒性


河崎孝弘, 山内俊一 - 糖尿病, 2005 - J-STAGE
文 献 1)Mayer PA(1993)Intermediary metabolism of fructose. Am J Clin
Nutr 58 : 754 S―765 S 2)Suarez G, Rajaram R, Oronsky AL, et
al.(1988)Nonen- zymatic glycation of bovine serum albumin by fructose ...
Cited by 1 - Related articles


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