- ►diabetesjournals.org WS Yang, CY Jeng, TJ Wu, S Tanaka, T Funahashi, … - Diabetes Care, 2002 - Am Diabetes Assoc OBJECTIVE—Adiponectin, a plasma protein exclusively synthesized and secreted by adipose
tissue, has recently been shown to have anti-inflammatory, antiatherogenic properties in vitro
and beneficial metabolic effects in animals. Lower plasma levels of adiponectin have ... Cited by 345 - Related articles - BL Direct - All 5 versions
- ►endojournals.org TP Combs, JA Wagner, J Berger, T Doebber, WJ Wang, … - Endocrinology, 2002 - Endocrine Soc MANY STUDIES HAVE shown that thiazolidinediones (TZDs) produce insulin sensitizing effects
in animal models (1, 2, 3, 4) and in insulin-resistant human subjects (5, 6, 7). It is now clear that
TZDs are high affinity ligands for the nuclear receptor, PPAR , which can transactivate ... Cited by 411 - Related articles - BL Direct - All 4 versions
N Maeda, M Takahashi, T Funahashi, S Kihara, H … - Diabetes, 2001 - Am Diabetes Assoc Insulin resistance and its dreaded consequence, type 2 diabetes, are major causes of
atherosclerosis. Adiponectin is an adipose-specific plasma protein that possesses anti-atherogenic
properties, such as the suppression of adhesion molecule expression in vascular ... Cited by 1017 - Related articles - BL Direct - All 4 versions
JG Yu, S Javorschi, AL Hevener, YT Kruszynska, RA … - Diabetes, 2002 - Am Diabetes Assoc The insulin-sensitizing effects of thiazolidinediones are thought to be mediated through peroxisome
proliferator-activated receptor-γ, a nuclear receptor that is highly abundant in adipose tissue.
It has been reported that adipocytes secrete a variety of proteins, including tumor necrosis ... Cited by 454 - Related articles - BL Direct - All 5 versions
H Hirose, T Kawai, Y Yamamoto, M Taniyama, M … - Metabolism, 2002 - Elsevier The aim of this study was to evaluate the effects of pioglitazone on clinical and metabolic
parameters, body fat distribution, and serum adiponectin, a recently discovered antiatherosclerotic
hormone, in Japanese patients with type 2 diabetes. Ten male patients aged 40 to 66 ... Cited by 194 - Related articles - BL Direct - All 7 versions
- ►ntu.edu.tw [PDF] WS Yang, PL Tsou, WJ Lee, DL Tseng, CL Chen, … - Journal of Molecular …, 2003 - Springer Abstract Adiponectin gene polymorphisms have recent- ly been reported to be associated with
obesity, insulin sensitivity, and the risk of type 2 diabetes. We examined a T94G polymorphism
of the adiponectin gene in 245 ostensibly normal nondiabetic subjects. The G allele fre- ... Cited by 73 - Related articles - BL Direct - All 4 versions
Y Yamamoto, H Hirose, I Saito, M Tomita, M … - Clinical …, 2002 - cs.portlandpress.com Adiponectin, which is secreted specifically by adipose tissue, has been shown to act as an
anti-atherosclerotic protein by direct effects on endothelial cells. Clinical studies have shown
that adiponectin levels are lower in individuals with obesity, diabetes and coronary artery ... Cited by 296 - Related articles - Cached - BL Direct - All 14 versions
- ►endojournals.org WS Yang, WJ Lee, T Funahashi, S Tanaka, Y … - Journal of Clinical …, 2001 - Endocrine Soc Adiponectin, an adipose tissue-specific plasma protein, was recently revealed to have anti-inflammatory
effects on the cellular components of vascular wall. Its plasma levels were significantly lower
in men than in women and lower in human subjects with obesity, type 2 diabetes mellitus, ... Cited by 752 - Related articles - BL Direct - All 5 versions
- ►physiology.org AS Lihn, T Ostergard, B Nyholm, SB … - American Journal of …, 2003 - Am Physiological Soc Adiponectin is suggested to be an important mediator of insulin resistance. Therefore, we investigated
the association between adiponectin and insulin sensitivity in 22 healthy first-degree relatives
(FDR) to type 2 diabetic patients and 13 matched control subjects. Subcutaneous adipose ... Cited by 77 - Related articles - BL Direct - All 4 versions
