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Scholar Results 1 - 10 of about 101 related to LaGasse: Successful prospective prediction of type 1 diabetes in schoolchildren through multiple.... (0.14 sec) 

Successful prospective prediction of type 1 diabetes in schoolchildren through …


JM LaGasse, MS Brantley, NJ Leech, RE Rowe, S … - Diabetes Care, 2002 - Am Diabetes Assoc
RESULTS—Six subjects developed diabetes (median interval 2.8 years), all from among the 12
individuals with multiple d-aab, representing 50% positive predictive value (95% CI 25–75%) and
100% sensitivity (58–100%). Among ...
Cited by 76 - Related articles - BL Direct - All 5 versions

Screening strategies for the identification of multiple antibody-positive relatives of …

- endojournals.org
JP Krischer, DD Cuthbertson, L Yu, T Orban, N … - Journal of Clinical …, 2003 - Endocrine Soc
There were 1010 (5.9%) relatives with a single autoantibody on initial screening and 394 (2.3%) with
two or more autoantibodies. GAA was more sensitive than ICA [GAA, 91% (357 of 394); ICA, 82% (324 of
394)] in the detection of multiple ...
Cited by 69 - Related articles - BL Direct - All 4 versions

Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics


P Achenbach, K Warncke, J Reiter, HE Naserke, AJK … - Diabetes, 2004 - Am Diabetes Assoc
Family history of type 1 diabetes and autoantibodies to the islet antigens insulin (IAA), glutamate
decarboxylase (GADA), and the protein tyrosine phosphatase-like protein IA-2 (IA-2A) are strong
predictors of type 1 diabetes, but ...
Cited by 91 - Related articles - BL Direct - All 6 versions

Karlsburg Type I diabetes risk study of a general population: frequencies and …


M Strebelow, M Schlosser, B Ziegler, I Rjasanowski, M … - Diabetologia, 1999 - Springer
Type I (insulin-dependent) diabetes mellitus is a chronic autoimmune disease characterized by selec-
tive destruction of the insulin-producing beta cells in the pancreatic islet, accompanied by
antibody forma- tion against ...
Cited by 52 - Related articles - BL Direct - All 3 versions

The Karlsburg Type 1 Diabetes Risk Study of a Normal Schoolchild Population: …

- endojournals.org
M Schlosser, M Strebelow, R Wassmuth, ML … - Journal of Clinical …, 2002 - Endocrine Soc
The intent of this study was to analyze the prevalence of diabetes-associated autoantibodies (AAbs)
at or above the 99 th percentile as well as their association with human leukocyte antigen
(HLA)-DQB1 alleles in a normal ...
Cited by 34 - Related articles - BL Direct - All 4 versions

[PDF] Genetic markers, humoral autoimmunity, and prediction of type 1 diabetes in …


P Kulmala, K Savola, H Reijonen, R Veijola, … - DIABETES-NEW …, 2000 - Am Diabetes Assoc
The relationships between genetic markers and dis- ease-associated autoantibodies were studied in an
un- selected population of 701 siblings of children with type 1 diabetes, and the predictive
characteristics of these markers ...
Cited by 69 - Related articles - BL Direct - All 5 versions

The First Signs of {beta}-Cell Autoimmunity Appear in Infancy in Genetically …

- endojournals.org
T Kimpimaki, A Kupila, AM Hamalainen, M … - Journal of Clinical …, 2001 - Endocrine Soc
Little is known about the timing of the etiological events and the preclinical process of type 1
diabetes during the first years of life in the general population. In this population-based
prospective birth cohort study, the ...
Cited by 117 - Related articles - BL Direct - All 5 versions

β-Cell autoimmunity, genetic susceptibility, and progression to type 1 diabetes in …

- diabetesjournals.org [PDF] 
P Kulmala, J Rahko, K Savola, P Vähäsalo, M … - Diabetes Care, 2001 - Am Diabetes Assoc
We have recently reported evidence of increased oxidative stress in nondiabetic first-degree
relatives of patients with type 1 diabetes (1). Ele- vated circulating markers of lipid peroxida-
tion and increased cellular ...
Cited by 26 - Related articles - BL Direct - All 5 versions

Natural history of {beta}-cell autoimmunity in young children with increased genetic …

- endojournals.org
T Kimpimaki, P Kulmala, K Savola, A Kupila, S … - Journal of Clinical …, 2002 - Endocrine Soc
The aim of this study was to evaluate the frequency and predictive value of diabetes-associated
autoantibodies, such as islet cell antibodies (ICA) and autoantibodies to insulin (IAA), GAD65
(GADA), and the IA-2 molecule ...
Cited by 71 - Related articles - BL Direct - All 5 versions

Brief communication: early appearance of islet autoantibodies predicts childhood …

- annals.org [PDF] 
M Hummel, E Bonifacio, S Schmid, M Walter … - Annals of internal …, 2004 - Am Coll Physicians
Brief Communication: Early Appearance of Islet Autoantibodies ... Predicts Childhood Type 1
Diabetes in Offspring of Diabetic Parents ... Michael Hummel, MD; Ezio Bonifacio, PhD; Sandra
Schmid, PhD; Markus Walter, MD; ...
Cited by 39 - Related articles - BL Direct - All 4 versions


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