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Scholar Results 1 - 10 of about 101 related to Libman: Changing prevalence of overweight children and adolescents at onset of insulin-treated.... (0.10 sec) 

Changing prevalence of overweight children and adolescents at onset of insulin- …


IM Libman, M Pietropaolo, SA Arslanian, RE … - Diabetes Care, 2003 - Am Diabetes Assoc
RESULTS—The prevalence of being overweight increased from 12.6% (period I) to 36.8% (period
II) (P = 0.0003); in whites from 2.9 to 16.6% (P = 0.04) and in blacks from 22 to 55% (P =
0.001); and in the age-group <11 years from 7.3 to 22.2% (P = 0.04) and age 11–18 years ...
Cited by 91 - Related articles - BL Direct - All 8 versions

Testing the accelerator hypothesis


M Kibirige, B Metcalf, R Renuka, TJ Wilkin - Diabetes Care, 2003 - Am Diabetes Assoc
OBJECTIVE—Previous reports have predicted greater risk of type 1 diabetes among people
who were heavier as young children. The Accelerator Hypothesis predicts earlier onset in heavier
people, without necessarily a change in risk, and views type 1 and type 2 diabetes as the ...
Cited by 101 - Related articles - BL Direct - All 6 versions

The accelerator hypothesis: weight gain as the missing link between type I and …


TJ Wilkin - Diabetologia, 2001 - Springer
The definitions need urgent revision. More than half of the patients with Type I diabetes present
in adulthood, when their onset is slow and many do not develop acidosis or require insulin for
many years [1]. Type II diabetes occurs in teenagers [2], some- times with keto-acidosis ...
Cited by 240 - Related articles - BL Direct - All 5 versions

[PDF] Obesity, increased linear growth, and risk of type 1 diabetes in children


E Hypponen, SM Virtanen, MG Kenward, M Knip, … - Diabetes Care, 2000 - Am Diabetes Assoc
Subjects All children under the age of 15 years with newly diagnosed type 1 diabetes were invited
to participate in the nationwide Childhood Diabetes in Finland case-control study from September
1986 to April 1989 (11). Of 801 affected children invited, 94% took part in the study. Blood ...
Cited by 136 - Related articles - BL Direct - All 8 versions

Testing the accelerator hypothesis: body size, β-cell function, and age at onset of …

- diabetesjournals.org
D Dabelea - Diabetes Care, 2006 - Am Diabetes Assoc
We thank Dr. Wilkin (1) for his valuable comments. Overall, we (2) did not observe the hypothesized
association between increasing BMI and younger age at onset of diabetes among US youth
with autoimmune diabetes. Our results were similar to a report from Birmingham, UK (3), ...
Cited by 42 - Related articles - BL Direct - All 7 versions

The 'accelerator hypothesis': relationship between weight, height, body mass index …


I Knerr, J Wolf, T Reinehr, R Stachow, M Grabert, E … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 2501–2504 DOI 10.1007/s00125-005-0033-2 SHORT
COMMUNICATION I. Knerr . J. Wolf . T. Reinehr . R. Stachow . M. Grabert . E. Schober . W. Rascher
. RW Holl . on behalf of the DPV Scientific Initiative of Germany and Austria ...
Cited by 40 - Related articles - All 5 versions

Insulin resistance in children and adolescents with type 1 diabetes mellitus: …


VK Jugendklinik, FS Str - Pediatric Diabetes - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 18 - Related articles - All 5 versions

Increasing body weight predicts the earlier onset of insulin-dependant diabetes in …


P Betts, J Mulligan, P Ward, B Smith, T Wilkin - Diabetic Medicine, 2005 - interscience.wiley.com
Aims and methods It has recently been hypothesized that weight gain in childhood accelerates
the onset of Type 1 diabetes, as well as increasing its risk, and that Type 1 diabetes and Type
2 diabetes may be one and the same disorder of insulin resistance. An explanation is ...
Cited by 69 - Related articles - All 4 versions

Braking the accelerator hypothesis?


JR Porter, TG Barrett - Diabetologia, 2004 - Springer
To the Editor: The accelerator hypothesis was first suggested in 2001 [1]. It postulates that Type
1 and Type 2 diabetes are not discrete but part of a spectrum of disease caused by three main
processes or accelerators; insulin resistance, autoimmuni- ty and constitution. It suggests ...
Cited by 23 - Related articles - BL Direct - All 4 versions

Evidence for heterogeneous pathogenesis of insulin-treated diabetes in black and …

- diabetesjournals.org
IM Libman, M Pietropaolo, SA Arslanian, RE … - Diabetes Care, 2003 - Am Diabetes Assoc
RESULTS—The black children had a higher prevalence of obesity (43 vs. 11%) and acanthosis
nigricans (21 vs. 1%) than white children and a lower prevalence of AAs. Compared with black
children who had AAs, those with no AAs were older and had a higher prevalence of ...
Cited by 26 - Related articles - BL Direct - All 8 versions


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