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Scholar Results 1 - 10 of about 101 related to Dandona: Insulin suppresses plasma concentration of vascular endothelial growth factor and.... (0.11 sec) 

Insulin suppresses plasma concentration of vascular endothelial growth factor and matrix …

- diabetesjournals.org
P Dandona, A Aljada, P Mohanty, H Ghanim, … - Diabetes Care, 2003 - Am Diabetes Assoc
OBJECTIVE—We recently demonstrated a potent anti-inflammatory and thus a
potential antiatherogenic effect of insulin in human aortic endothelial cells
and mononuclear cells at physiologically relevant concentrations. We have ...
Cited by 81 - Related articles - BL Direct - All 6 versions

Glucose intake induces an increase in activator protein 1 and early growth response 1 binding …

- ajcn.org
A Aljada, H Ghanim, P Mohanty, T Syed, A … - American journal of clinical nutrition, 2004 - Am Soc Nutrition
Background: Glucose intake has been shown to cause an increase in intranuclear
nuclear factor- B and a decrease in inhibitor B that are consistent with a
proinflammatory effect. We investigated the effect of glucose intake on 2 ...
Cited by 83 - Related articles - BL Direct - All 7 versions

Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr …


A Aljada, H Ghanim, P Mohanty, N Kapur, P … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc
We have recently demonstrated that an infusion of a low dose of insulin reduces
the intranuclear NF- B (a pro-inflammatory transcription factor) content in MNC
while also reducing the p;asma concentration of NF- B dependent ...
Cited by 166 - Related articles - All 4 versions

Differential effects of glucose and alcohol on reactive oxygen species generation and …


S Dhindsa, D Tripathy, P Mohanty, H Ghanim, … - Metabolism, 2004 - Elsevier
It has previously been shown that oral intake of 300 calories of glucose (75 g),
lipid, or protein increases reactive oxygen species (ROS) generation by
polymorphonuclear cells (PMNL) and mononuclear cells (MNCs). We ...
Cited by 74 - Related articles - All 12 versions

Oral insulin supplementation attenuates atherosclerosis progression in apolipoprotein E- …

- ahajournals.org
R Shamir, N Shehadeh, M Rosenblat, O … - Arteriosclerosis, thrombosis, and vascular biology, 2003 - Am Heart Assoc
Methods and Results— One-month-old male E 0 mice were orally supplemented with
human insulin (0.1, 0.5, and 1 U/mL) or placebo for 3 months. At the end of the
study, serum and macrophage oxidative stress and atherosclerosis ...
Cited by 59 - Related articles - BL Direct - All 9 versions

[CITATION] Insulin reduces the pro-inflammatory transcription factor, activation protein-1 (AP-1), in …


H Ghanim, P Mohanty, A Aljada, S Chowhan, … - Diabetes, 2001
Cited by 29 - Related articles

Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation …

- ahajournals.org
A Chaudhuri, D Janicke, MF Wilson, D … - Circulation, 2004 - Am Heart Assoc
Methods and Results— Thirty-two patients receiving reteplase were randomly
assigned infusions of either insulin at 2.5 U/h, dextrose, and potassium (GIK)
or normal saline and potassium (C) for 48 hours. Plasma concentrations of ...
Cited by 210 - Related articles - BL Direct - All 8 versions

Initiation of insulin therapy reduces serum concentrations of high-sensitivity C-reactive …


K Takebayashi, Y Aso, T Inukai - Metabolism, 2004 - Elsevier
Atherosclerosis has highly important chronic inflammatory aspects. We
investigated anti-inflammatory effects upon initiating insulin therapy by
measuring serum high-sensitivity C-reactive protein (hsCRP) and plasma ...
Cited by 51 - Related articles - All 10 versions

Lack of insulin receptor substrate-2 causes progressive neointima formation in response to …

- ahajournals.org
T Kubota, N Kubota, M Moroi, Y Terauchi, T … - Circulation, 2003 - Am Heart Assoc
From the Third Department of Internal Medicine, Toho University School of
Medicine, Ohashi Hospital, Tokyo, Japan (TK, MM, AN, TY); the Department of
Metabolic Diseases, Graduate School of Medicine, University of Tokyo, ...
Cited by 61 - Related articles - All 7 versions

Effect of insulin on human aortic endothelial nitric oxide synthase


A Aljada, P Dandona - Metabolism, 2000 - Elsevier
It has recently been shown that insulin induces vasodilation in human arteries
and veins in vivo. This effect of insulin has been shown to be a direct one on
the human vein. In view of these observations and the fact insulin-induced ...
Cited by 120 - Related articles - BL Direct - All 8 versions


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