T Tsunekawa, T Hayashi, Y Suzuki, H Matsui-Hirai, … - Diabetes care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—A total of 17 elderly patients with type 2 diabetes received
12 weeks of treatment with glimepiride. Homeostasis assessment model of insulin resistance
(HOMA-IR), homeostasis assessment model of β-cell function, HbA 1c , C-peptide in 24-h ... Cited by 68 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] S Nagasaka, A Taniguchi, Y Aiso, T Yatagai, T … - Diabetes care, 2003 - Am Diabetes Assoc Although the number of children and youth with type 2 diabetes is in- creasing, a clear case definition
that describes children with type 2 diabetes at presentation remains elusive. Most initial diagnoses
are decided on the clinical pic- ture at presentation (1). Characteristics and risk factors ... Cited by 10 - Related articles - BL Direct - All 6 versions
S Fukuen, M Iwaki, A Yasui, M Makishima, M … - Journal of Biological …, 2005 - ASBMB Sulfonylurea (SU) agents, including glimepiride and glibenclamide, are the most widely used
oral hypoglycemic drugs, which stimulate insulin secretion primarily by binding to the SU receptor
on the plasma membrane of pancreatic β-cells. Thiazolidinediones, such as pioglitazone ... Cited by 38 - Related articles - All 5 versions
A Haupt, C Kausch, D Dahl, O Bachmann, M … - Diabetes care, 2002 - Am Diabetes Assoc RESULTS—Glimepiride had no significant effect on basal glycogen synthesis; in contrast, glimepiride
caused a dose-dependent increase of insulin-stimulated glycogen synthesis, with a maximal
effect of 39.97 ± 8.4% (mean ± SEM, n = 4, P < 0,02). The time course of this glimepiride ... Cited by 12 - Related articles - BL Direct - All 5 versions
K Inukai, M Watanabe, Y Nakashima, N Takata, A … - … and Biophysical Research …, 2005 - Elsevier Glimepiride, a third-generation sulfonylurea (SU), exerts its effects mainly by stimulating insulin
secretion but has also been shown to have pleiotropic effects. Recent clinical studies showed
glimepiride to enhance insulin sensitivity. In the present study, to clarify the mechanism by ... Cited by 15 - Related articles - All 3 versions
Y Yamamoto, H Hirose, K Miyashita, K Nishikai, I Saito, … - Metabolism, 2002 - Elsevier Adiponectin is an adipocyte-derived protein, which possesses an anti-atherosclerotic action
and improves insulin sensitivity. Peroxisome proliferator-activated receptor gamma (PPAR[gamma
]) regulates the transcription of many adipocyte-specific genes. A Pro12Ala polymorphism ... Cited by 60 - Related articles - BL Direct - All 7 versions
M Suzuki, A Kanazawa, M Shiba, H Kojima, Y … - Journal of diabetes and its …, 2000 - Elsevier To investigate whether insulin resistance is associated with diabetic microangiopathies in type
2 diabetes mellitus, insulin sensitivity was measured in 133 type 2 diabetic subjects with or without
diabetic retinopathy and/or nephropathy. Insulin sensitivity was measured by steady-state ... Cited by 22 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Korytkowski, A Thomas, L Reid, MB Tedesco, WE … - Diabetes Care, 2002 - Am Diabetes Assoc RESULTS—Glimepiride resulted in a 2.4-mmol/l decrease in fasting plasma glucose (P =
0.04) that was correlated with reductions in postabsorptive endogenous glucose production
(EGP) (16.4 ± 0.6 vs. 13.5 ± 0.5 μmol · kg −1 · min −1 , P = 0.01) (r = 0.21, P = 0.01). ... Cited by 44 - Related articles - BL Direct - All 5 versions
K Inukai, M Watanabe, Y Nakashima, T Sawa, N … - Diabetes research and …, 2005 - Elsevier We investigated the efficacy of glimepiride, a third-generation sulfonylurea (SU), in Japanese
type 2 diabetic patients in whom glycemic control had been inadequate with a conventional
SU, gliclazide or glibenclamide. A total of 172 Japanese type 2 diabetic patients (HbA1C ... Cited by 8 - Related articles - All 10 versions
O Porzio, L Marlier, M Federici, ML Hribal, R … - Molecular and cellular …, 1999 - Elsevier In the present study we examined the effect of sulfonylurea on the expression of the glucose
transporter GLUT2 and the glucose phosphorylating enzyme Glucokinase (GK) in βTC6-F7
cells; furthermore, we studied the modifications induced by sulfonylurea on glucose- ... Cited by 12 - Related articles - All 5 versions
