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Scholar Results 1 - 10 of about 101 related to Kipnes: Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients.... (0.10 sec) 

Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients with …


M Kipnes, P Dandona, D Tripathy, JG Still, G … - Diabetes Care, 2003 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Eighteen patients with type 2 diabetes were
enrolled in this randomized, single-blind, placebo-controlled, three-way
crossover, dose-escalation study. A single dose of each of the following ...
Cited by 52 - Related articles - BL Direct - All 6 versions

Oral modified insulin (HIM2) in patients with type 1 diabetes mellitus: results from a phase I/II …


S Clement, P Dandona, JG Still, G Kosutic - Metabolism, 2004 - Elsevier
An effective, orally administered insulin product would be of substantial
benefit in the treatment of patients with diabetes mellitus. This phase I/II
clinical trial was the first to investigate the safety and effectiveness of ...
Cited by 43 - Related articles - All 10 versions

Oral insulin product hexyl-insulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: the …


S Clement, JG Still, G Kosutic, RG McAllister - Diabetes Technology & Therapeutics, 2002 - liebertonline.com
Page 1. DIABETES TECHNOLOGY & THERAPEUTICS Volume 4, Number 4, 2002 © Mary Ann
Liebert, Inc. Oral Insulin Product Hexyl-Insulin Monoconjugate 2 ...
Cited by 33 - Related articles - BL Direct - All 3 versions

Dose-response effect of a single administration of oral hexyl-insulin monoconjugate 2 in …

- diabetesjournals.org
E Wajcberg, Y Miyazaki, C Triplitt, E … - Diabetes care, 2004 - Am Diabetes Assoc
RESULTS—Fasting plasma insulin (7 μU/ml) increased to a maximum of 102, 321,
and 561 μU/ml at 60 min after all three HIM2 doses (0.125, 0.5, and 0.75 mg/kg,
respectively). A dose-related decrease in basal EGP was observed as the ...
Cited by 11 - Related articles - BL Direct - All 6 versions

A novel per-oral insulin formulation: proof of concept study in non-diabetic subjects


M Kidron, S Dinh, Y Menachem, R Abbas, B … - Diabetic Medicine, 2004 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 26 - Related articles - BL Direct - All 5 versions

Development of oral insulin: progress and current status


JG Still - Diabetes Metabolism and Reviews - interscience.wiley.com
NOBEX oral drug delivery technology is centered on modification of peptides,
proteins and small organic molecules by attachment of one or more amphiphilic
oligomers. Attachment of these oligomers results in stability to enzymatic ...
Cited by 57 - Related articles - BL Direct - All 2 versions

NIN-058


HIM Treatment - Drugs of the Future, 2004 - journals.prous.com
Currently available insulin preparations for the treat- ment of diabetes
mellitus are unable to mimic the pat- terns of endogenous insulin secretion, and
normo- glycemia cannot be achieved. Inadequate control of hyperglycemia, ...
Related articles

Dose-response relationships of inhaled insulin delivered via the Aerodose insulin inhaler …


D Kim, S Mudaliar, S Chinnapongse, N Chu, … - Diabetes Care, 2003 - Am Diabetes Assoc
RESULTS—Inhaled insulin exhibited significantly shorter time-to-peak insulin
levels (T max 77 ± 66 vs. 193 ± 104 min, P < 0.001) and time-to-peak metabolic
effects (T GIRmax 240 ± 94 vs. 353 ± 60 min, P < 0.001) compared with ...
Cited by 32 - Related articles - BL Direct - All 6 versions

HIM2 Treatment of Type Insulin Analog


HI Monoconjugate - Drugs of the Future, 2004 - journals.prous.com
Currently available insulin preparations for the treatment of diabetes mellitus
are unable to mimic the patterns of endogenous insulin secretion, and
normoglycemia cannot be achieved. Inadequate control of hyperglycemia, ...
Related articles

Beneficial effects of addition of oral spray insulin (Oralin) on insulin secretion and …


J Guevara-Aguirre, M Guevara, J Saavedra, M … - Diabetes Technology & Therapeutics, 2004 - liebertonline.com
Page 1. DIABETES TECHNOLOGY & THERAPEUTICS Volume 6, Number 1, 2004 © Mary Ann Liebert,
Inc. Beneficial Effects of Addition of Oral Spray Insulin ...
Cited by 16 - Related articles - BL Direct - All 3 versions


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