A Himmelmann, J Jendle, A Mellén, AH Petersen, … - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—Pharmacokinetic results for evaluable subjects were derived from serum insulin
profiles. The amount of insulin absorbed during the first 6 h after dosing (area under the exogenous
serum insulin curve from 0 to 6 h [AUC (0–6 h) ]) was significantly greater in smokers ... Cited by 100 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org RR Henry, SRD Mudaliar, WC Howland III, N Chu, … - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—Inhaled insulin showed area under the curve (AUC) (0–360 min) values that were
significantly greater for healthy subjects than for asthmatic subjects (P = 0.013), whereas no difference
was observed for maximum concentration (C max ) in the two groups. A greater reduction ... Cited by 98 - Related articles - BL Direct - All 5 versions
A McElduff, LE Mather, PC Kam, P … - British journal of clinical …, 2005 - pubmedcentral.nih.gov Normally healthy adult men (n = 11) and women (n = 9) received a single dose of inhaled human
insulin, equivalent to ~6 IU subcutaneous, using the AERx® insulin Diabetes Management System
(iDMS), during and following recovery from an URTI. The first dose was administered with ... Cited by 35 - Related articles - All 6 versions
- ►diabetesjournals.org RHA Becker, S Sha, AD Frick, RJ Fountaine - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—Before smoking cessation, maximum insulin concentration (C max ) and area under
the curve (AUC) for insulin concentration time (AUC-Insulin 0–360 ) with inhaled insulin were
higher, and time to C max (t max ) shorter, in smokers than nonsmokers (C max 26.8 vs. ... Cited by 59 - Related articles - BL Direct - All 6 versions
K Hermansen, T Ronnemaa, AH Petersen, S Bellaire, … - Diabetes Care, 2004 - 万方数据资源系统 OBJECTIVE:-To compare the glycemic control of inhaled insulin via the AERx insulin diabetes
management system (iDMS) with that of subcutaneous (SC) insulin, both combined with NPH
insulin at bedtime, in patients with type 2 diabetes. RESEARCH DESIGNAND METHODS- ... Cited by 79 - Related articles - BL Direct - All 5 versions
RA Gerber, JC Cappelleri, IA Kourides, RA Gelfand - Diabetes Care, 2001 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Subjects with type 1 diabetes participated in a 12-week
open-label trial and were randomized to either an inhaled insulin regimen or a subcutaneous
insulin regimen. Subjects (n = 69) were asked to complete a 15-item self-administered ... Cited by 101 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org J Rosenstock, JC Cappelleri, B Bolinder, RA … - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—Of the 60 patients who received inhaled insulin during the parent studies, 85.0%
(n = 51) chose to continue treatment, 13.3% (n = 8) switched to subcutaneous insulin, and
1.7% (n = 1) did not continue. Of the 61 patients who received subcutaneous insulin, ... Cited by 132 - Related articles - BL Direct - All 12 versions
- ►diabetesjournals.org K Rave, S Bott, L Heinemann, S Sha, RHA Becker, … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—INH had a faster onset of action than both RHI and ILP, as indicated by shorter time
to early half-maximal effect (32 vs. 48 and 41 min, respectively; P < 0.001 for IHN vs. RHI and
P < 0.05 for IHN vs. ILP). Time to maximal effect was comparable between INH and ILP ... Cited by 112 - Related articles - All 7 versions
- ►endojournals.org SE Fineberg, T Kawabata, D Finco-Kent, C Liu, … - Journal of Clinical …, 2005 - Endocrine Soc Research Design and Methods: Insulin antibody data from initial phase II/III trials were analyzed
comparing the efficacy and safety of inhaled insulin with various agents, including sc insulin.
Additionally, data from a 24-month extension of the phase III studies were examined. Data ... Cited by 119 - Related articles - All 6 versions
GA Brunner, B Balent, M Ellmerer, L Schaupp, A … - Diabetologia, 2001 - Springer In order to optimise insulin treatment, insulin ana- logues for subcutaeous injection have been
designed recently [1]. Substantial efforts have also been direct- ed towards finding alternative
routes for insulin ad- ministration [2]. The AERx insulin Diabetes Man- agement System ( ... Cited by 89 - Related articles - BL Direct - All 4 versions
